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Author: Eytan Ruppin

  • ORCiD: http://orcid.org/0000-0002-7862-3940
  • Most recently observed institution: Cancer Data Science Lab (CDSL), National Cancer Institute, National Institute of Health, Bethesda, MD 20892

Rankings

  • All-time downloads: 88,907 (rank: 1,962 )
  • Categories:
    • bioinformatics: 4,303 (rank: 3,558 (tie) )
    • cancer biology: 16,140 (rank: 95 )
    • genetics: 747 (rank: 22,519 (tie) )
    • genomics: 992 (rank: 26,248 (tie) )
    • infectious diseases: 63,843 (rank: 938 )
    • systems biology: 2,882 (rank: 1,697 )

Downloads per author, site-wide

Preprints

Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection

infectious diseases more details view paper
  • Downloaded 43,148 times
  • Download rankings, all-time:
    • Site-wide: 180
    • In infectious diseases: 71
  • Year to date:
    • Site-wide: 53
  • Since beginning of last month:
    • Site-wide: 73

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection in a large cohort

infectious diseases more details view paper
  • Downloaded 17,821 times
  • Download rankings, all-time:
    • Site-wide: 517
    • In infectious diseases: 187
  • Year to date:
    • Site-wide: 156
  • Since beginning of last month:
    • Site-wide: 255

Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing

cancer biology more details view paper
  • Downloaded 4,248 times
  • Download rankings, all-time:
    • Site-wide: 3,364
    • In cancer biology: 45
  • Year to date:
    • Site-wide: 51,273
  • Since beginning of last month:
    • Site-wide: 39,878

Identification of drugs associated with reduced severity of COVID-19: A case-control study in a large population

infectious diseases more details view paper
  • Downloaded 2,874 times
  • Download rankings, all-time:
    • Site-wide: 5,861
    • In infectious diseases: 1,072
  • Year to date:
    • Site-wide: 3,122
  • Since beginning of last month:
    • Site-wide: 7,771

The Landscape of Receptor-Mediated Precision Cancer Combination Therapy: A Single-Cell Perspective

bioinformatics more details view paper
  • Downloaded 1,586 times
  • Download rankings, all-time:
    • Site-wide: 14,109
    • In bioinformatics: 1,572
  • Year to date:
    • Site-wide: 11,044
  • Since beginning of last month:
    • Site-wide: 9,618

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

cancer biology more details view paper
  • Downloaded 1,577 times
  • Download rankings, all-time:
    • Site-wide: 14,258
    • In cancer biology: 299
  • Year to date:
    • Site-wide: 134,850
  • Since beginning of last month:
    • Site-wide: 115,500

CSI-Microbes: Identifying cell-type specific intracellular microbes from single-cell RNA-seq data

cancer biology more details view paper
  • Downloaded 1,353 times
  • Download rankings, all-time:
    • Site-wide: 18,107
    • In cancer biology: 397
  • Year to date:
    • Site-wide: 11,695
  • Since beginning of last month:
    • Site-wide: 5,558

Whole exome precision oncology targeting synthetic lethal vulnerabilities across the tumor transcriptome

cancer biology more details view paper
  • Downloaded 1,325 times
  • Download rankings, all-time:
    • Site-wide: 18,686
    • In cancer biology: 415
  • Year to date:
    • Site-wide: 40,258
  • Since beginning of last month:
    • Site-wide: 83,196

Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets

systems biology more details view paper
  • Downloaded 1,273 times
  • Download rankings, all-time:
    • Site-wide: 19,840
    • In systems biology: 369
  • Year to date:
    • Site-wide: 3,782
  • Since beginning of last month:
    • Site-wide: 22,940

Beyond synthetic lethality: charting the landscape of clinically relevant genetic interactions in cancer

systems biology more details view paper
  • Downloaded 1,153 times
  • Download rankings, all-time:
    • Site-wide: 23,066
    • In systems biology: 431
  • Year to date:
    • Site-wide: 131,134
  • Since beginning of last month:
    • Site-wide: 147,632

Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin

cancer biology more details view paper
  • Downloaded 1,013 times
  • Download rankings, all-time:
    • Site-wide: 28,093
    • In cancer biology: 708
  • Year to date:
    • Site-wide: 43,597
  • Since beginning of last month:
    • Site-wide: 70,657

Strain Level Microbial Detection and Quantification with Applications to Single Cell Metagenomics

bioinformatics more details view paper
  • Downloaded 934 times
  • Download rankings, all-time:
    • Site-wide: 31,636
    • In bioinformatics: 3,470
  • Year to date:
    • Site-wide: 18,408
  • Since beginning of last month:
    • Site-wide: 8,047

Predicting cancer prognosis and drug response from the tumor microbiome

cancer biology more details view paper
  • Downloaded 905 times
  • Download rankings, all-time:
    • Site-wide: 33,203
    • In cancer biology: 882
  • Year to date:
    • Site-wide: 15,276
  • Since beginning of last month:
    • Site-wide: 13,544

Division of labor between YAP and TAZ in non-small cell lung cancer

cancer biology more details view paper
  • Downloaded 900 times
  • Download rankings, all-time:
    • Site-wide: 33,440
    • In cancer biology: 888
  • Year to date:
    • Site-wide: 25,508
  • Since beginning of last month:
    • Site-wide: 21,143

Deconvolving clinically relevant cellular immune crosstalk from bulk gene expression using CODEFACS and LIRICS

bioinformatics more details view paper
  • Downloaded 875 times
  • Download rankings, all-time:
    • Site-wide: 34,788
    • In bioinformatics: 3,768
  • Year to date:
    • Site-wide: 6,715
  • Since beginning of last month:
    • Site-wide: 16,058

Predicting tissue-specific gene expression from whole blood transcriptome

genetics more details view paper
  • Downloaded 747 times
  • Download rankings, all-time:
    • Site-wide: 43,798
    • In genetics: 1,893
  • Year to date:
    • Site-wide: 69,172
  • Since beginning of last month:
    • Site-wide: 112,087

A landscape of synergistic drug combinations in non-small-cell lung cancer

cancer biology more details view paper
  • Downloaded 738 times
  • Download rankings, all-time:
    • Site-wide: 44,544
    • In cancer biology: 1,218
  • Year to date:
    • Site-wide: 8,757
  • Since beginning of last month:
    • Site-wide: 34,577

Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity

cancer biology more details view paper
  • Downloaded 671 times
  • Download rankings, all-time:
    • Site-wide: 50,860
    • In cancer biology: 1,442
  • Year to date:
    • Site-wide: 104,343
  • Since beginning of last month:
    • Site-wide: 75,545

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

cancer biology more details view paper
  • Downloaded 656 times
  • Download rankings, all-time:
    • Site-wide: 52,384
    • In cancer biology: 1,492
  • Year to date:
    • Site-wide: 22,482
  • Since beginning of last month:
    • Site-wide: 27,453

Criticality in Tumor Evolution and Clinical Outcome

cancer biology more details view paper
  • Downloaded 645 times
  • Download rankings, all-time:
    • Site-wide: 53,558
    • In cancer biology: 1,534
  • Year to date:
    • Site-wide: 156,180
  • Since beginning of last month:
    • Site-wide: 153,688

A transcriptionally distinct subpopulation of healthy acinar cells exhibit features of pancreatic progenitors and PDAC

genomics more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 68,454
    • In genomics: 4,746
  • Year to date:
    • Site-wide: 14,736
  • Since beginning of last month:
    • Site-wide: 65,962

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival

bioinformatics more details view paper
  • Downloaded 502 times
  • Download rankings, all-time:
    • Site-wide: 73,060
    • In bioinformatics: 6,823
  • Year to date:
    • Site-wide: 161,606
  • Since beginning of last month:
    • Site-wide: 162,025

Epigenomic tumor evolution modeling with single-cell methylation data profiling

cancer biology more details view paper
  • Downloaded 473 times
  • Download rankings, all-time:
    • Site-wide: 77,981
    • In cancer biology: 2,288
  • Year to date:
    • Site-wide: 17,613
  • Since beginning of last month:
    • Site-wide: 25,817

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

genomics more details view paper
  • Downloaded 462 times
  • Download rankings, all-time:
    • Site-wide: 79,954
    • In genomics: 5,248
  • Year to date:
    • Site-wide: 156,943
  • Since beginning of last month:
    • Site-wide: 159,065

Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

systems biology more details view paper
  • Downloaded 456 times
  • Download rankings, all-time:
    • Site-wide: 81,211
    • In systems biology: 1,814
  • Year to date:
    • Site-wide: 18,523
  • Since beginning of last month:
    • Site-wide: 10,166

Cross-species identification of cancer-resistance associated genes uncovers their relevance to human cancer risk

cancer biology more details view paper
  • Downloaded 451 times
  • Download rankings, all-time:
    • Site-wide: 82,142
    • In cancer biology: 2,414
  • Year to date:
    • Site-wide: 18,934
  • Since beginning of last month:
    • Site-wide: 28,060

Higher prevalence of homologous recombination-deficiency in lung squamous carcinoma from African Americans

cancer biology more details view paper
  • Downloaded 428 times
  • Download rankings, all-time:
    • Site-wide: 86,759
    • In cancer biology: 2,583
  • Year to date:
    • Site-wide: 121,354
  • Since beginning of last month:
    • Site-wide: 89,765

Repurposing CAR targets in solid tumors via a pan-cancer single-cell transcriptome analysis

bioinformatics more details view paper
  • Downloaded 406 times
  • Download rankings, all-time:
    • Site-wide: 91,260
    • In bioinformatics: 8,043
  • Year to date:
    • Site-wide: 22,286
  • Since beginning of last month:
    • Site-wide: 1,688

Immune determinants of the association between tumor mutational burden and immunotherapy response across cancer types

cancer biology more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 123,425
    • In cancer biology: 3,749
  • Year to date:
    • Site-wide: 39,127
  • Since beginning of last month:
    • Site-wide: 72,595

Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias

cancer biology more details view paper
  • Downloaded 187 times
  • Download rankings, all-time:
    • Site-wide: 145,841
    • In cancer biology: 4,472
  • Year to date:
    • Site-wide: 63,734
  • Since beginning of last month:
    • Site-wide: 118,458

Sex biases in cancer and autoimmune disease incidence are correlated across human tissues

cancer biology more details view paper
  • Downloaded 182 times
  • Download rankings, all-time:
    • Site-wide: 146,944
    • In cancer biology: 4,511
  • Year to date:
    • Site-wide: 65,641
  • Since beginning of last month:
    • Site-wide: 66,244

Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function

cancer biology more details view paper
  • Downloaded 113 times
  • Download rankings, all-time:
    • Site-wide: 159,093
    • In cancer biology: 4,893
  • Year to date:
    • Site-wide: 104,895
  • Since beginning of last month:
    • Site-wide: 14,641

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