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Author: Xiuqing Guo

  • ORCiD: http://orcid.org/0000-0002-5264-5068
  • Most recently observed institution: The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Rankings

  • All-time downloads: 56,155 (rank: 2,441 )
  • Categories:
    • bioinformatics: 321 (rank: 31,065 (tie) )
    • epidemiology: 1,127 (rank: 8,163 (tie) )
    • gastroenterology: 797 (rank: 366 (tie) )
    • genetic and genomic medicine: 3,723 (rank: 241 )
    • genetics: 30,956 (rank: 185 )
    • genomics: 17,746 (rank: 651 )
    • hiv aids: 1,121 (rank: 59 (tie) )
    • physiology: 364 (rank: 4,435 (tie) )

Downloads per author, site-wide

Preprints

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 11,519 times
  • Download rankings, all-time:
    • Site-wide: 662
    • In genetics: 17
  • Year to date:
    • Site-wide: 3,000
  • Since beginning of last month:
    • Site-wide: 5,248

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

genomics more details view paper
  • Downloaded 8,181 times
  • Download rankings, all-time:
    • Site-wide: 1,042
    • In genomics: 94
  • Year to date:
    • Site-wide: 2,193
  • Since beginning of last month:
    • Site-wide: 4,808

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,247 times
  • Download rankings, all-time:
    • Site-wide: 3,697
    • In genomics: 416
  • Year to date:
    • Site-wide: 59,019
  • Since beginning of last month:
    • Site-wide: 42,343

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,082 times
  • Download rankings, all-time:
    • Site-wide: 3,975
    • In genetics: 168
  • Year to date:
    • Site-wide: 54,308
  • Since beginning of last month:
    • Site-wide: 72,291

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 2,882 times
  • Download rankings, all-time:
    • Site-wide: 4,361
    • In genomics: 489
  • Year to date:
    • Site-wide: 7,793
  • Since beginning of last month:
    • Site-wide: 10,076

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,851 times
  • Download rankings, all-time:
    • Site-wide: 8,388
    • In genetics: 393
  • Year to date:
    • Site-wide: 87,764
  • Since beginning of last month:
    • Site-wide: 88,900

Identification of type 2 diabetes loci in 433,540 East Asian individuals

genetics more details view paper
  • Downloaded 1,821 times
  • Download rankings, all-time:
    • Site-wide: 8,603
    • In genetics: 403
  • Year to date:
    • Site-wide: 29,929
  • Since beginning of last month:
    • Site-wide: 25,127

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
  • Downloaded 1,660 times
  • Download rankings, all-time:
    • Site-wide: 9,872
    • In genetics: 469
  • Year to date:
    • Site-wide: 64,880
  • Since beginning of last month:
    • Site-wide: 45,358

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

genetics more details view paper
  • Downloaded 1,455 times
  • Download rankings, all-time:
    • Site-wide: 11,956
    • In genetics: 583
  • Year to date:
    • Site-wide: 6,991
  • Since beginning of last month:
    • Site-wide: 5,351

Genetic architecture of gene expression traits across diverse populations

genomics more details view paper
  • Downloaded 1,222 times
  • Download rankings, all-time:
    • Site-wide: 15,627
    • In genomics: 1,611
  • Year to date:
    • Site-wide: 79,528
  • Since beginning of last month:
    • Site-wide: 65,285

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

genetics more details view paper
  • Downloaded 1,198 times
  • Download rankings, all-time:
    • Site-wide: 16,076
    • In genetics: 793
  • Year to date:
    • Site-wide: 52,478
  • Since beginning of last month:
    • Site-wide: 70,758

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,165 times
  • Download rankings, all-time:
    • Site-wide: 16,765
    • In genetics: 821
  • Year to date:
    • Site-wide: 6,231
  • Since beginning of last month:
    • Site-wide: 6,192

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 1,121 times
  • Download rankings, all-time:
    • Site-wide: 17,732
    • In hiv aids: 8
  • Year to date:
    • Site-wide: 7,924
  • Since beginning of last month:
    • Site-wide: 5,454

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,083 times
  • Download rankings, all-time:
    • Site-wide: 18,670
    • In genetic and genomic medicine: 64
  • Year to date:
    • Site-wide: 7,747
  • Since beginning of last month:
    • Site-wide: 9,283

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.

genetic and genomic medicine more details view paper
  • Downloaded 1,017 times
  • Download rankings, all-time:
    • Site-wide: 20,455
    • In genetic and genomic medicine: 69
  • Year to date:
    • Site-wide: 1,082
  • Since beginning of last month:
    • Site-wide: 3,927

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 877 times
  • Download rankings, all-time:
    • Site-wide: 25,360
    • In genetics: 1,223
  • Year to date:
    • Site-wide: 19,255
  • Since beginning of last month:
    • Site-wide: 10,875

Machine learning enables new insights into clinical significance of and genetic contributions to liver fat accumulation

genetic and genomic medicine more details view paper
  • Downloaded 873 times
  • Download rankings, all-time:
    • Site-wide: 25,530
    • In genetic and genomic medicine: 83
  • Year to date:
    • Site-wide: 10,889
  • Since beginning of last month:
    • Site-wide: 16,888

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

genetics more details view paper
  • Downloaded 840 times
  • Download rankings, all-time:
    • Site-wide: 26,897
    • In genetics: 1,302
  • Year to date:
    • Site-wide: 93,077
  • Since beginning of last month:
    • Site-wide: 96,645

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 825 times
  • Download rankings, all-time:
    • Site-wide: 27,574
    • In genetics: 1,335
  • Year to date:
    • Site-wide: 62,638
  • Since beginning of last month:
    • Site-wide: 71,245

rs641738C>T near MBOAT7 promotes steatosis, NASH, fibrosis and hepatocellular carcinoma in non-alcoholic fatty liver disease: a meta-analysis

gastroenterology more details view paper
  • Downloaded 797 times
  • Download rankings, all-time:
    • Site-wide: 28,964
    • In gastroenterology: 22
  • Year to date:
    • Site-wide: 31,362
  • Since beginning of last month:
    • Site-wide: 41,165

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 794 times
  • Download rankings, all-time:
    • Site-wide: 29,119
    • In genetics: 1,409
  • Year to date:
    • Site-wide: 14,029
  • Since beginning of last month:
    • Site-wide: 10,559

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 751 times
  • Download rankings, all-time:
    • Site-wide: 31,472
    • In genomics: 2,814
  • Year to date:
    • Site-wide: 94,111
  • Since beginning of last month:
    • Site-wide: 108,316

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

genomics more details view paper
  • Downloaded 747 times
  • Download rankings, all-time:
    • Site-wide: 31,712
    • In genomics: 2,824
  • Year to date:
    • Site-wide: 71,386
  • Since beginning of last month:
    • Site-wide: 85,686

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 713 times
  • Download rankings, all-time:
    • Site-wide: 33,757
    • In genetics: 1,636
  • Year to date:
    • Site-wide: 120,047
  • Since beginning of last month:
    • Site-wide: 109,216

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

genetics more details view paper
  • Downloaded 617 times
  • Download rankings, all-time:
    • Site-wide: 40,892
    • In genetics: 1,943
  • Year to date:
    • Site-wide: 5,002
  • Since beginning of last month:
    • Site-wide: 15,504

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

genetics more details view paper
  • Downloaded 613 times
  • Download rankings, all-time:
    • Site-wide: 41,204
    • In genetics: 1,953
  • Year to date:
    • Site-wide: 77,047
  • Since beginning of last month:
    • Site-wide: 71,094

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 506 times
  • Download rankings, all-time:
    • Site-wide: 52,036
    • In genomics: 4,036
  • Year to date:
    • Site-wide: 120,060
  • Since beginning of last month:
    • Site-wide: 116,900

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

genetics more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 61,053
    • In genetics: 2,840
  • Year to date:
    • Site-wide: 76,917
  • Since beginning of last month:
    • Site-wide: 78,447

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

genetics more details view paper
  • Downloaded 396 times
  • Download rankings, all-time:
    • Site-wide: 67,467
    • In genetics: 3,098
  • Year to date:
    • Site-wide: 61,364
  • Since beginning of last month:
    • Site-wide: 70,581

Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

epidemiology more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 72,026
    • In epidemiology: 3,024
  • Year to date:
    • Site-wide: 87,560
  • Since beginning of last month:
    • Site-wide: 70,561

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Humans and Mice

physiology more details view paper
  • Downloaded 364 times
  • Download rankings, all-time:
    • Site-wide: 72,800
    • In physiology: 549
  • Year to date:
    • Site-wide: 71,820
  • Since beginning of last month:
    • Site-wide: 94,394

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

bioinformatics more details view paper
  • Downloaded 321 times
  • Download rankings, all-time:
    • Site-wide: 80,797
    • In bioinformatics: 7,397
  • Year to date:
    • Site-wide: 55,841
  • Since beginning of last month:
    • Site-wide: 39,077

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

genetic and genomic medicine more details view paper
  • Downloaded 320 times
  • Download rankings, all-time:
    • Site-wide: 81,123
    • In genetic and genomic medicine: 285
  • Year to date:
    • Site-wide: 23,642
  • Since beginning of last month:
    • Site-wide: 20,822

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

epidemiology more details view paper
  • Downloaded 301 times
  • Download rankings, all-time:
    • Site-wide: 84,910
    • In epidemiology: 3,494
  • Year to date:
    • Site-wide: 77,391
  • Since beginning of last month:
    • Site-wide: 79,547

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

epidemiology more details view paper
  • Downloaded 293 times
  • Download rankings, all-time:
    • Site-wide: 86,599
    • In epidemiology: 3,556
  • Year to date:
    • Site-wide: 39,612
  • Since beginning of last month:
    • Site-wide: 53,718

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

genetics more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 86,914
    • In genetics: 3,933
  • Year to date:
    • Site-wide: 49,549
  • Since beginning of last month:
    • Site-wide: None

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

genetics more details view paper
  • Downloaded 274 times
  • Download rankings, all-time:
    • Site-wide: 90,695
    • In genetics: 4,085
  • Year to date:
    • Site-wide: 117,365
  • Since beginning of last month:
    • Site-wide: 101,039

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

genetics more details view paper
  • Downloaded 268 times
  • Download rankings, all-time:
    • Site-wide: 92,035
    • In genetics: 4,141
  • Year to date:
    • Site-wide: 123,272
  • Since beginning of last month:
    • Site-wide: 112,705

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

genetics more details view paper
  • Downloaded 259 times
  • Download rankings, all-time:
    • Site-wide: 93,981
    • In genetics: 4,217
  • Year to date:
    • Site-wide: 130,419
  • Since beginning of last month:
    • Site-wide: 126,762

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 210 times
  • Download rankings, all-time:
    • Site-wide: 104,866
    • In genomics: 6,130
  • Year to date:
    • Site-wide: 98,746
  • Since beginning of last month:
    • Site-wide: 75,307

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

genetic and genomic medicine more details view paper
  • Downloaded 178 times
  • Download rankings, all-time:
    • Site-wide: 111,777
    • In genetic and genomic medicine: 497
  • Year to date:
    • Site-wide: 12,724
  • Since beginning of last month:
    • Site-wide: 37,309

BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion

genetic and genomic medicine more details view paper
  • Downloaded 171 times
  • Download rankings, all-time:
    • Site-wide: 113,402
    • In genetic and genomic medicine: 512
  • Year to date:
    • Site-wide: 13,305
  • Since beginning of last month:
    • Site-wide: 41,735

The Socioeconomic Gradient in Epigenetic Aging Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study

epidemiology more details view paper
  • Downloaded 165 times
  • Download rankings, all-time:
    • Site-wide: 114,651
    • In epidemiology: 4,715
  • Year to date:
    • Site-wide: 13,933
  • Since beginning of last month:
    • Site-wide: 3,981

Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL Study

genetic and genomic medicine more details view paper
  • Downloaded 81 times
  • Download rankings, all-time:
    • Site-wide: 130,159
    • In genetic and genomic medicine: 639
  • Year to date:
    • Site-wide: 32,156
  • Since beginning of last month:
    • Site-wide: 23,930

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