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Author: Cathryn Lewis

Rankings

  • All-time downloads: 61,071 (rank: 2,954 )
  • Categories:
    • bioinformatics: 292 (rank: 37,146 (tie) )
    • epidemiology: 7,043 (rank: 2,340 )
    • genetic and genomic medicine: 6,694 (rank: 174 )
    • genetics: 28,090 (rank: 251 )
    • genomics: 11,860 (rank: 1,738 )
    • neuroscience: 493 (rank: 52,032 (tie) )
    • psychiatry and clinical psychology: 6,599 (rank: 87 )

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Preprints

Context Matters! Depression following childbirth or a chronic disease diagnosis shows specific risk factor profiles.

psychiatry and clinical psychology more details view paper

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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

genomics more details view paper
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
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ukbtools: An R package to manage and query UK Biobank data

epidemiology more details view paper
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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

genetics more details view paper
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Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

genetic and genomic medicine more details view paper
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    • Site-wide: 8,818
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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

genetics more details view paper
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    • In genetics: 577
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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

genetics more details view paper
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    • In genetics: 639
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
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Transforming summary statistics from logistic regression to the liability scale: application to genetic and environmental risk scores

epidemiology more details view paper
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Pharmacogenetic testing through the direct-to-consumer genetic testing company 23andMe

genetics more details view paper
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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
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Evaluation of Polygenic Prediction Methodology within a Reference-Standardized Framework

genomics more details view paper
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Identifying Potential Causal Risk Factors for Self-Harm: A Polygenic Risk Scoring and Mendelian Randomisation Approach

epidemiology more details view paper
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    • Site-wide: 21,927
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Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?

genetics more details view paper
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Atypical depression shares genetic predisposition with immuno-metabolic traits: a population-based study

genetic and genomic medicine more details view paper
  • Downloaded 991 times
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    • In genetic and genomic medicine: 118
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Pharmacogenetics of antidepressant response: a polygenic approach

genetics more details view paper
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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 766 times
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    • Site-wide: 38,834
    • In genetic and genomic medicine: 170
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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

genetics more details view paper
  • Downloaded 758 times
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The Maudsley Environmental Risk Score for Psychosis

epidemiology more details view paper
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Impute.me: an open source, non-profit tool for using data from DTC genetic testing to calculate and interpret polygenic risk scores.

genetics more details view paper
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Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

psychiatry and clinical psychology more details view paper
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    • In psychiatry and clinical psychology: 174
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The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 616 times
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A Tool for Translating Polygenic Scores onto the Absolute Scale Using Summary Statistics

genetic and genomic medicine more details view paper
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Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

genetics more details view paper
  • Downloaded 580 times
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Delineating the Genetic Component of Gene Expression in Major Depression

genomics more details view paper
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Calculating variant penetrance using family history of disease and population data

genetic and genomic medicine more details view paper
  • Downloaded 552 times
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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

psychiatry and clinical psychology more details view paper
  • Downloaded 522 times
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    • In psychiatry and clinical psychology: 230
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Multiple measures of depression to enhance validity of Major Depressive Disorder in the UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 516 times
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Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
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Cannabis-associated symptom profiles in patients with first episode psychosis and population controls

neuroscience more details view paper
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Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: meta-analysis of three treatment cohorts.

genetics more details view paper
  • Downloaded 479 times
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    • Site-wide: 70,048
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Genetic variation in the Major Histocompatibility Complex and association with depression

genetics more details view paper
  • Downloaded 457 times
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    • In genetics: 3,172
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Predictors of intestinal inflammation in asymptomatic first-degree relatives of patients with Crohn's disease

epidemiology more details view paper
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Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures

epidemiology more details view paper
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Age-related changes in physiology in individuals with bipolar disorder

psychiatry and clinical psychology more details view paper
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A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping

genetic and genomic medicine more details view paper
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Phenotypic Associations and Shared Genetic Etiology between Bipolar Disorder and Cardiometabolic Traits

psychiatry and clinical psychology more details view paper
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Lifetime depression and age-related changes in body composition, cardiovascular function, grip strength and lung function: sex-specific analyses in the UK Biobank

epidemiology more details view paper
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Whats in a diagnosis? A genetic decomposition of major depression.

genetic and genomic medicine more details view paper
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Investigating an in-silico approach for prioritizing antidepressant drug prescription based on drug-induced expression profiles and predicted gene expression

bioinformatics more details view paper
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Investigating pleiotropy between depression and autoimmune diseases using the UK Biobank

psychiatry and clinical psychology more details view paper
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Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity

genetic and genomic medicine more details view paper
  • Downloaded 237 times
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    • Site-wide: 122,881
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Cost-effectiveness of genetic and clinical predictors for choosing combined psychotherapy and pharmacotherapy in major depression

psychiatry and clinical psychology more details view paper
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Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

psychiatry and clinical psychology more details view paper
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Examining the association between family status and depression in the UK Biobank

epidemiology more details view paper
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The consequences of a year of the COVID-19 pandemic for the mental health of young adult twins in England and Wales

psychiatry and clinical psychology more details view paper
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Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

genetic and genomic medicine more details view paper
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Latent subtypes of manic or irritable episode symptoms in two population-based cohorts

psychiatry and clinical psychology more details view paper
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Anxiety disorders and age-related changes in physiology

psychiatry and clinical psychology more details view paper
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Exploring polygenic-environment and residual-environment interactions for depressive symptoms within the UK Biobank

genetic and genomic medicine more details view paper
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Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK

epidemiology more details view paper
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