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Author: Cathryn M Lewis

  • ORCiD: http://orcid.org/0000-0002-8249-8476
  • Most recently observed institution: Social, Genetic and Developmental Psychiatry Centre, King's College London, London, GB, NIHR Maudsley BRC, King's College London, London, GB, Department of Medical & Molecular Genetics, King's College London, London, GB

Rankings

  • All-time downloads: 52,676 (rank: 2,623 )
  • Categories:
    • bioinformatics: 216 (rank: 35,328 (tie) )
    • epidemiology: 6,015 (rank: 2,088 )
    • genetic and genomic medicine: 4,070 (rank: 188 )
    • genetics: 26,410 (rank: 248 )
    • genomics: 11,035 (rank: 1,630 )
    • neuroscience: 445 (rank: 46,542 (tie) )
    • psychiatry and clinical psychology: 4,485 (rank: 83 )

Downloads per author, site-wide

Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
  • Downloaded 4,757 times
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    • Site-wide: 2,130
    • In genomics: 224
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,520 times
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    • Site-wide: 2,281
    • In genetics: 85
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    • Site-wide: 36,978
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    • Site-wide: 49,846

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

genomics more details view paper
  • Downloaded 3,579 times
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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
  • Downloaded 2,577 times
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    • Site-wide: 5,095
    • In genetics: 230
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ukbtools: An R package to manage and query UK Biobank data

epidemiology more details view paper
  • Downloaded 2,276 times
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
  • Downloaded 2,120 times
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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

genetics more details view paper
  • Downloaded 2,023 times
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    • In genetics: 346
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Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

genetic and genomic medicine more details view paper
  • Downloaded 1,585 times
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    • In genetic and genomic medicine: 39
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,458 times
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    • Site-wide: 11,850
    • In genomics: 1,290
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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

genetics more details view paper
  • Downloaded 1,368 times
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    • Site-wide: 13,087
    • In genetics: 646
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Pharmacogenetic testing through the direct-to-consumer genetic testing company 23andMe

genetics more details view paper
  • Downloaded 1,248 times
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    • Site-wide: 15,042
    • In genetics: 747
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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
  • Downloaded 1,214 times
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    • Site-wide: 15,692
    • In genetics: 776
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Transforming summary statistics from logistic regression to the liability scale: application to genetic and environmental risk scores

epidemiology more details view paper
  • Downloaded 1,183 times
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    • Site-wide: 16,289
    • In epidemiology: 1,020
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    • Site-wide: 13,424
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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

genetics more details view paper
  • Downloaded 1,070 times
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    • Site-wide: 18,915
    • In genetics: 923
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Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?

genetics more details view paper
  • Downloaded 954 times
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    • Site-wide: 22,302
    • In genetics: 1,076
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Identifying Potential Causal Risk Factors for Self-Harm: A Polygenic Risk Scoring and Mendelian Randomisation Approach

epidemiology more details view paper
  • Downloaded 936 times
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Pharmacogenetics of antidepressant response: a polygenic approach

genetics more details view paper
  • Downloaded 893 times
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    • Site-wide: 24,587
    • In genetics: 1,187
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Evaluation of Polygenic Prediction Methodology within a Reference-Standardized Framework

genomics more details view paper
  • Downloaded 751 times
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Atypical depression shares genetic predisposition with immuno-metabolic traits: a population-based study

genetic and genomic medicine more details view paper
  • Downloaded 736 times
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    • Site-wide: 32,229
    • In genetic and genomic medicine: 103
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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

genetics more details view paper
  • Downloaded 717 times
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    • Site-wide: 33,355
    • In genetics: 1,620
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The Maudsley Environmental Risk Score for Psychosis

epidemiology more details view paper
  • Downloaded 641 times
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    • Site-wide: 38,780
    • In epidemiology: 1,863
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    • Site-wide: 91,203
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Impute.me: an open source, non-profit tool for using data from DTC genetic testing to calculate and interpret polygenic risk scores.

genetics more details view paper
  • Downloaded 579 times
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    • Site-wide: 44,101
    • In genetics: 2,070
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    • Site-wide: 38,129
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Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

psychiatry and clinical psychology more details view paper
  • Downloaded 566 times
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    • Site-wide: 45,398
    • In psychiatry and clinical psychology: 148
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    • Site-wide: 22,039

The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 527 times
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    • Site-wide: 49,304
    • In genetics: 2,308
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    • Site-wide: 54,646
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Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

genetics more details view paper
  • Downloaded 524 times
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    • Site-wide: 49,727
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    • Site-wide: 108,475
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    • Site-wide: 99,588

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 502 times
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    • Site-wide: 52,245
    • In genetic and genomic medicine: 167
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    • Site-wide: 10,586
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    • Site-wide: 8,867

Delineating the Genetic Component of Gene Expression in Major Depression

genomics more details view paper
  • Downloaded 490 times
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    • Site-wide: 53,746
    • In genomics: 4,137
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    • Site-wide: 34,945
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Cannabis-associated symptom profiles in patients with first episode psychosis and population controls

neuroscience more details view paper
  • Downloaded 445 times
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    • In neuroscience: 8,949
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Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: meta-analysis of three treatment cohorts.

genetics more details view paper
  • Downloaded 444 times
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    • Site-wide: 59,831
    • In genetics: 2,783
  • Year to date:
    • Site-wide: 99,002
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    • Site-wide: 99,623

Genetic variation in the Major Histocompatibility Complex and association with depression

genetics more details view paper
  • Downloaded 429 times
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    • Site-wide: 61,906
    • In genetics: 2,877
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Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
  • Downloaded 427 times
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    • Site-wide: 62,249
    • In psychiatry and clinical psychology: 199
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    • Site-wide: 41,666
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Predictors of intestinal inflammation in asymptomatic first-degree relatives of patients with Crohn's disease

epidemiology more details view paper
  • Downloaded 406 times
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Multiple measures of depression to enhance validity of Major Depressive Disorder in the UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 389 times
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    • In genetic and genomic medicine: 224
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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

psychiatry and clinical psychology more details view paper
  • Downloaded 347 times
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    • Site-wide: 75,638
    • In psychiatry and clinical psychology: 243
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Age-related changes in physiology in individuals with bipolar disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 307 times
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    • Site-wide: 83,286
    • In psychiatry and clinical psychology: 276
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    • Site-wide: 5,642
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Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures

epidemiology more details view paper
  • Downloaded 307 times
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    • Site-wide: 36,631
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A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping

genetic and genomic medicine more details view paper
  • Downloaded 298 times
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Phenotypic Associations and Shared Genetic Etiology between Bipolar Disorder and Cardiometabolic Traits

psychiatry and clinical psychology more details view paper
  • Downloaded 260 times
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Whats in a diagnosis? A genetic decomposition of major depression.

genetic and genomic medicine more details view paper
  • Downloaded 226 times
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Investigating an in-silico approach for prioritizing antidepressant drug prescription based on drug-induced expression profiles and predicted gene expression

bioinformatics more details view paper
  • Downloaded 216 times
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Cost-effectiveness of genetic and clinical predictors for choosing combined psychotherapy and pharmacotherapy in major depression

psychiatry and clinical psychology more details view paper
  • Downloaded 180 times
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    • Site-wide: 111,142
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Examining the association between family status and depression in the UK Biobank

epidemiology more details view paper
  • Downloaded 147 times
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    • Site-wide: 117,982
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Investigating pleiotropy between depression and autoimmune diseases using the UK Biobank

psychiatry and clinical psychology more details view paper
  • Downloaded 144 times
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Calculating variant penetrance using family history of disease and population data

genetic and genomic medicine more details view paper
  • Downloaded 138 times
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    • Site-wide: 119,679
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Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

psychiatry and clinical psychology more details view paper
  • Downloaded 134 times
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    • Site-wide: 120,549
    • In psychiatry and clinical psychology: 551
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Lifetime depression and age-related changes in body composition, cardiovascular function, grip strength and lung function: sex-specific analyses in the UK Biobank

epidemiology more details view paper
  • Downloaded 119 times
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    • Site-wide: 123,431
    • In epidemiology: 5,003
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    • Site-wide: 21,944

Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

genetic and genomic medicine more details view paper
  • Downloaded 101 times
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Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and depressive symptoms in men

genetic and genomic medicine more details view paper
  • Downloaded 95 times
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