Author: Mark J Adams

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Preprints

Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

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Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

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Mental health during the COVID-19 pandemic in two longitudinal UK population cohorts

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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Factors associated with sharing email information and mental health survey participation in large population cohorts

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Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

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Sex-Stratified Genome-Wide Association Study of Multisite Chronic Pain in UK Biobank

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Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

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Genome-wide Association Study of Multisite Chronic Pain in UK Biobank

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Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

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Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

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Mental Health in UK Biobank Revised

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Cognitive functioning and lifetime Major Depressive Disorder in UK Biobank

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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

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A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

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Characterization of Age and Polarity at Onset in Bipolar Disorder

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Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

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A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorder

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Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

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A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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Associations Between Major Psychiatric Disorder Polygenic Risk Scores and Blood-Based Markers in UK Biobank

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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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The Influence of Phenotyping Method on Neuroimaging Associations with Depression in UK Biobank

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DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

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Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

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Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK Biobank

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Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.

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White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

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Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome

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Genome-by-Trauma Interaction Effects in Depression

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Early-life inflammatory markers and subsequent episodes of depression and psychotic experiences in the ALSPAC birth cohort

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Classification accuracy of structural and functional connectomes across different depressive phenotypes

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