Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 70,235 bioRxiv papers from 306,680 authors.

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • In genetics: 14 out of 3,897
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  • Site-wide: 5,112 out of 70,242
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  • Site-wide: 8,638 out of 70,242

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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  • Site-wide: 753 out of 70,242
  • In genetics: 69 out of 3,897
• Year to date:
  • Site-wide: 4,335 out of 70,242
• Since beginning of last month:
  • Site-wide: 5,490 out of 70,242

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

• Downloaded 2,959 times
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  • Site-wide: 1,281 out of 70,242
  • In genomics: 294 out of 4,700
• Year to date:
  • Site-wide: 1,216 out of 70,242
• Since beginning of last month:
  • Site-wide: 4,228 out of 70,242

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

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  • In genetics: 183 out of 3,897
• Year to date:
  • Site-wide: 40,591 out of 70,242
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  • Site-wide: 14,272 out of 70,242

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • In genetics: 312 out of 3,897
• Year to date:
  • Site-wide: 53,615 out of 70,242
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  • Site-wide: 27,950 out of 70,242

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

• Downloaded 1,485 times
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  • In genetics: 360 out of 3,897
• Year to date:
  • Site-wide: 7,061 out of 70,242
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  • Site-wide: 4,651 out of 70,242

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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  • In genetics: 381 out of 3,897
• Year to date:
  • Site-wide: 7,443 out of 70,242
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  • Site-wide: 15,455 out of 70,242

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

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  • In genetics: 508 out of 3,897
• Year to date:
  • Site-wide: 20,953 out of 70,242
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  • Site-wide: 26,901 out of 70,242

Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

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  • In neuroscience: 1,403 out of 12,633
• Year to date:
  • Site-wide: 21,869 out of 70,242
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  • Site-wide: 48,532 out of 70,242

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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  • In genetics: 685 out of 3,897
• Year to date:
  • Site-wide: 32,126 out of 70,242
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  • Site-wide: 40,986 out of 70,242

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

• Downloaded 761 times
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  • Site-wide: 12,540 out of 70,242
  • In genetics: 867 out of 3,897
• Year to date:
  • Site-wide: 9,815 out of 70,242
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  • Site-wide: 31,679 out of 70,242

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

• Downloaded 720 times
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  • Site-wide: 13,603 out of 70,242
  • In genetics: 940 out of 3,897
• Year to date:
  • Site-wide: 59,299 out of 70,242
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  • Site-wide: 58,771 out of 70,242

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

• Downloaded 645 times
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  • Site-wide: 15,913 out of 70,242
  • In genetics: 1,089 out of 3,897
• Year to date:
  • Site-wide: 10,167 out of 70,242
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  • Site-wide: 30,120 out of 70,242

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 641 times
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  • In genetics: 1,098 out of 3,897
• Year to date:
  • Site-wide: 24,280 out of 70,242
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  • Site-wide: 47,437 out of 70,242

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 624 times
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  • In genetics: 1,142 out of 3,897
• Year to date:
  • Site-wide: 50,585 out of 70,242
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  • Site-wide: 58,415 out of 70,242

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

• Downloaded 565 times
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  • Site-wide: 19,162 out of 70,242
  • In genomics: 2,292 out of 4,700
• Year to date:
  • Site-wide: 34,175 out of 70,242
• Since beginning of last month:
  • Site-wide: 61,331 out of 70,242

Factors associated with sharing email information and mental health survey participation in two large population cohorts

• Downloaded 564 times
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  • Site-wide: 19,242 out of 70,242
  • In genetics: 1,277 out of 3,897
• Year to date:
  • Site-wide: 47,378 out of 70,242
• Since beginning of last month:
  • Site-wide: 63,902 out of 70,242

Genome-wide Association Study of Multisite Chronic Pain in UK Biobank

• Downloaded 487 times
• Download rankings, all-time:
  • Site-wide: 23,201 out of 70,242
  • In genetics: 1,537 out of 3,897
• Year to date:
  • Site-wide: 10,565 out of 70,242
• Since beginning of last month:
  • Site-wide: 46,594 out of 70,242

A validation of the diathesis-stress model for depression in Generation Scotland.

• Downloaded 469 times
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  • Site-wide: 24,304 out of 70,242
  • In genomics: 2,631 out of 4,700
• Year to date:
  • Site-wide: 21,771 out of 70,242
• Since beginning of last month:
  • Site-wide: 33,335 out of 70,242

Educational attainment causally impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study in ~ 780,000 study participants

• Downloaded 448 times
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  • Site-wide: 25,618 out of 70,242
  • In epidemiology: 348 out of 1,556
• Year to date:
  • Site-wide: 29,495 out of 70,242
• Since beginning of last month:
  • Site-wide: 28,162 out of 70,242

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

• Downloaded 433 times
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  • Site-wide: 26,630 out of 70,242
  • In genetics: 1,723 out of 3,897
• Year to date:
  • Site-wide: 22,161 out of 70,242
• Since beginning of last month:
  • Site-wide: 42,527 out of 70,242

Accelerated Epigenetic Ageing in Major Depressive Disorder

• Downloaded 426 times
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  • Site-wide: 27,085 out of 70,242
  • In genomics: 2,837 out of 4,700
• Year to date:
  • Site-wide: 35,554 out of 70,242
• Since beginning of last month:
  • Site-wide: 58,523 out of 70,242

Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

• Downloaded 399 times
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  • Site-wide: 29,171 out of 70,242
  • In neuroscience: 5,012 out of 12,633
• Year to date:
  • Site-wide: 52,327 out of 70,242
• Since beginning of last month:
  • Site-wide: 43,582 out of 70,242

Genetic correlations between pain phenotypes and depression and neuroticism

• Downloaded 327 times
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  • Site-wide: 35,755 out of 70,242
  • In genetics: 2,214 out of 3,897
• Year to date:
  • Site-wide: 64,755 out of 70,242
• Since beginning of last month:
  • Site-wide: 22,304 out of 70,242

Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

• Downloaded 273 times
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  • Site-wide: 41,642 out of 70,242
  • In genetics: 2,515 out of 3,897
• Year to date:
  • Site-wide: 26,621 out of 70,242
• Since beginning of last month:
  • Site-wide: 66,687 out of 70,242

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 266 times
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  • Site-wide: 42,419 out of 70,242
  • In genetics: 2,560 out of 3,897
• Year to date:
  • Site-wide: 67,278 out of 70,242
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  • Site-wide: 48,885 out of 70,242

Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

• Downloaded 263 times
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  • Site-wide: 42,897 out of 70,242
  • In genetics: 2,580 out of 3,897
• Year to date:
  • Site-wide: 48,992 out of 70,242
• Since beginning of last month:
  • Site-wide: 67,907 out of 70,242

A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

• Downloaded 185 times
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  • Site-wide: 53,528 out of 70,242
  • In genetics: 3,143 out of 3,897
• Year to date:
  • Site-wide: 18,506 out of 70,242
• Since beginning of last month:
  • Site-wide: 56,742 out of 70,242

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

• Downloaded 155 times
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  • Site-wide: 57,965 out of 70,242
  • In neuroscience: 10,351 out of 12,633
• Year to date:
  • Site-wide: 34,249 out of 70,242
• Since beginning of last month:
  • Site-wide: 20,422 out of 70,242

Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

• Downloaded 148 times
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  • Site-wide: 59,062 out of 70,242
  • In bioinformatics: 6,196 out of 6,887
• Year to date:
  • Site-wide: 18,688 out of 70,242
• Since beginning of last month:
  • Site-wide: 46,733 out of 70,242

Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.

• Downloaded 144 times
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  • Site-wide: 59,607 out of 70,242
  • In genetics: 3,444 out of 3,897
• Year to date:
  • Site-wide: 41,289 out of 70,242
• Since beginning of last month:
  • Site-wide: 46,530 out of 70,242