Author: Mark J. Adams

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

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Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

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Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

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Factors associated with sharing email information and mental health survey participation in two large population cohorts

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Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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Genome-wide Association Study of Multisite Chronic Pain in UK Biobank

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A validation of the diathesis-stress model for depression in Generation Scotland.

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Educational attainment causally impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study in ~ 780,000 study participants

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Accelerated Epigenetic Ageing in Major Depressive Disorder

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

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A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

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Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

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Genetic correlations between pain phenotypes and depression and neuroticism

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

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Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

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Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.

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White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

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