Author: Mark J Adams

Downloads per author, site-wide

Preprints

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 4,581 times
• Download rankings, all-time:
  • Site-wide: 2,472
  • In genetics: 87
• Year to date:
  • Site-wide: 36,008
• Since beginning of last month:
  • Site-wide: 40,130

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

• Downloaded 3,621 times
• Download rankings, all-time:
  • Site-wide: 3,477
  • In genomics: 379
• Year to date:
  • Site-wide: 39,307
• Since beginning of last month:
  • Site-wide: 44,907

Mental health during the COVID-19 pandemic in two longitudinal UK population cohorts

• Downloaded 3,049 times
• Download rankings, all-time:
  • Site-wide: 4,428
  • In psychiatry and clinical psychology: 16
• Year to date:
  • Site-wide: 2,046
• Since beginning of last month:
  • Site-wide: 3,417

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,606 times
• Download rankings, all-time:
  • Site-wide: 5,550
  • In genetics: 244
• Year to date:
  • Site-wide: 69,558
• Since beginning of last month:
  • Site-wide: 55,122

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

• Downloaded 2,078 times
• Download rankings, all-time:
  • Site-wide: 7,748
  • In genetics: 348
• Year to date:
  • Site-wide: 41,023
• Since beginning of last month:
  • Site-wide: 23,840

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,901 times
• Download rankings, all-time:
  • Site-wide: 8,835
  • In genetics: 395
• Year to date:
  • Site-wide: 78,963
• Since beginning of last month:
  • Site-wide: 67,864

Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

• Downloaded 1,785 times
• Download rankings, all-time:
  • Site-wide: 9,709
  • In genetic and genomic medicine: 38
• Year to date:
  • Site-wide: 3,578
• Since beginning of last month:
  • Site-wide: 6,492

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

• Downloaded 1,732 times
• Download rankings, all-time:
  • Site-wide: 10,148
  • In genetics: 465
• Year to date:
  • Site-wide: 60,702
• Since beginning of last month:
  • Site-wide: 51,596

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

• Downloaded 1,432 times
• Download rankings, all-time:
  • Site-wide: 13,470
  • In genetics: 631
• Year to date:
  • Site-wide: 46,994
• Since beginning of last month:
  • Site-wide: 26,694

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

• Downloaded 1,234 times
• Download rankings, all-time:
  • Site-wide: 16,826
  • In genetics: 801
• Year to date:
  • Site-wide: 75,147
• Since beginning of last month:
  • Site-wide: 76,259

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 1,202 times
• Download rankings, all-time:
  • Site-wide: 17,487
  • In genetics: 829
• Year to date:
  • Site-wide: 5,155
• Since beginning of last month:
  • Site-wide: 10,589

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

• Downloaded 881 times
• Download rankings, all-time:
  • Site-wide: 27,461
  • In genetics: 1,292
• Year to date:
  • Site-wide: 107,729
• Since beginning of last month:
  • Site-wide: 99,199

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

• Downloaded 872 times
• Download rankings, all-time:
  • Site-wide: 27,907
  • In genetics: 1,311
• Year to date:
  • Site-wide: 124,419
• Since beginning of last month:
  • Site-wide: 119,896

Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

• Downloaded 790 times
• Download rankings, all-time:
  • Site-wide: 32,015
  • In epidemiology: 1,653
• Year to date:
  • Site-wide: 49,962
• Since beginning of last month:
  • Site-wide: 40,735

Factors associated with sharing email information and mental health survey participation in large population cohorts

• Downloaded 759 times
• Download rankings, all-time:
  • Site-wide: 33,809
  • In genetics: 1,584
• Year to date:
  • Site-wide: 109,445
• Since beginning of last month:
  • Site-wide: 113,358

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

• Downloaded 752 times
• Download rankings, all-time:
  • Site-wide: 34,258
  • In genetics: 1,605
• Year to date:
  • Site-wide: 122,817
• Since beginning of last month:
  • Site-wide: 108,819

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 735 times
• Download rankings, all-time:
  • Site-wide: 35,355
  • In genetics: 1,654
• Year to date:
  • Site-wide: 132,416
• Since beginning of last month:
  • Site-wide: 128,561

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

• Downloaded 695 times
• Download rankings, all-time:
  • Site-wide: 38,191
  • In genetics: 1,769
• Year to date:
  • Site-wide: 81,859
• Since beginning of last month:
  • Site-wide: 75,961

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

• Downloaded 646 times
• Download rankings, all-time:
  • Site-wide: 42,020
  • In genomics: 3,438
• Year to date:
  • Site-wide: 135,436
• Since beginning of last month:
  • Site-wide: 96,867

Genome-wide Association Study of Multisite Chronic Pain in UK Biobank

• Downloaded 638 times
• Download rankings, all-time:
  • Site-wide: 42,698
  • In genetics: 1,963
• Year to date:
  • Site-wide: 95,443
• Since beginning of last month:
  • Site-wide: 132,677

Sex-Stratified Genome-Wide Association Study of Multisite Chronic Pain in UK Biobank

• Downloaded 561 times
• Download rankings, all-time:
  • Site-wide: 50,166
  • In genetic and genomic medicine: 189
• Year to date:
  • Site-wide: 17,599
• Since beginning of last month:
  • Site-wide: 47,192

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

• Downloaded 560 times
• Download rankings, all-time:
  • Site-wide: 50,238
  • In genetics: 2,282
• Year to date:
  • Site-wide: 118,855
• Since beginning of last month:
  • Site-wide: 129,647

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

• Downloaded 491 times
• Download rankings, all-time:
  • Site-wide: 58,626
  • In genetics: 2,651
• Year to date:
  • Site-wide: 64,018
• Since beginning of last month:
  • Site-wide: 92,720

Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

• Downloaded 475 times
• Download rankings, all-time:
  • Site-wide: 60,762
  • In neuroscience: 8,944
• Year to date:
  • Site-wide: 131,534
• Since beginning of last month:
  • Site-wide: 96,745

Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

• Downloaded 455 times
• Download rankings, all-time:
  • Site-wide: 63,569
  • In genetics: 2,872
• Year to date:
  • Site-wide: 75,240
• Since beginning of last month:
  • Site-wide: 82,433

Mental Health in UK Biobank Revised

• Downloaded 449 times
• Download rankings, all-time:
  • Site-wide: 64,523
  • In epidemiology: 2,798
• Year to date:
  • Site-wide: 50,283
• Since beginning of last month:
  • Site-wide: 33,885

Cognitive functioning and lifetime Major Depressive Disorder in UK Biobank

• Downloaded 448 times
• Download rankings, all-time:
  • Site-wide: 64,544
  • In psychiatry and clinical psychology: 220
• Year to date:
  • Site-wide: 62,924
• Since beginning of last month:
  • Site-wide: 47,709

A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

• Downloaded 424 times
• Download rankings, all-time:
  • Site-wide: 68,442
  • In genetics: 3,089
• Year to date:
  • Site-wide: 129,438
• Since beginning of last month:
  • Site-wide: 137,638

Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

• Downloaded 409 times
• Download rankings, all-time:
  • Site-wide: 70,898
  • In psychiatry and clinical psychology: 242
• Year to date:
  • Site-wide: 14,064
• Since beginning of last month:
  • Site-wide: 35,024

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

• Downloaded 352 times
• Download rankings, all-time:
  • Site-wide: 81,286
  • In genetics: 3,627
• Year to date:
  • Site-wide: 138,084
• Since beginning of last month:
  • Site-wide: 137,910

Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

• Downloaded 345 times
• Download rankings, all-time:
  • Site-wide: 82,501
  • In genetics: 3,679
• Year to date:
  • Site-wide: 139,024
• Since beginning of last month:
  • Site-wide: 128,206

A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

• Downloaded 290 times
• Download rankings, all-time:
  • Site-wide: 94,259
  • In genetics: 4,138
• Year to date:
  • Site-wide: 130,860
• Since beginning of last month:
  • Site-wide: 106,583

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 259 times
• Download rankings, all-time:
  • Site-wide: 101,277
  • In genetics: 4,420
• Year to date:
  • Site-wide: 90,177
• Since beginning of last month:
  • Site-wide: 112,107

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

• Downloaded 250 times
• Download rankings, all-time:
  • Site-wide: 103,499
  • In genomics: 6,114
• Year to date:
  • Site-wide: 132,012
• Since beginning of last month:
  • Site-wide: 137,159

DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorder

• Downloaded 229 times
• Download rankings, all-time:
  • Site-wide: 108,380
  • In psychiatry and clinical psychology: 455
• Year to date:
  • Site-wide: 66,858
• Since beginning of last month:
  • Site-wide: 56,353

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

• Downloaded 229 times
• Download rankings, all-time:
  • Site-wide: 108,420
  • In neuroscience: 16,631
• Year to date:
  • Site-wide: 141,531
• Since beginning of last month:
  • Site-wide: 127,279

Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5.

• Downloaded 206 times
• Download rankings, all-time:
  • Site-wide: 113,848
  • In genetics: 4,849
• Year to date:
  • Site-wide: 138,225
• Since beginning of last month:
  • Site-wide: 132,649

Associations Between Major Psychiatric Disorder Polygenic Risk Scores and Blood-Based Markers in UK Biobank

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 117,389
  • In psychiatry and clinical psychology: 521
• Year to date:
  • Site-wide: 55,347
• Since beginning of last month:
  • Site-wide: 56,236

White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

• Downloaded 178 times
• Download rankings, all-time:
  • Site-wide: 120,548
  • In neuroscience: 18,417
• Year to date:
  • Site-wide: 141,034
• Since beginning of last month:
  • Site-wide: 142,413

Characterization of Age and Polarity at Onset in Bipolar Disorder

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 121,916
  • In psychiatry and clinical psychology: 556
• Year to date:
  • Site-wide: 26,104
• Since beginning of last month:
  • Site-wide: 23,259

Novel polygenic risk score links depression-related cortical transcriptomic changes to brain morphology and symptom severity

• Downloaded 170 times
• Download rankings, all-time:
  • Site-wide: 122,162
  • In genetic and genomic medicine: 618
• Year to date:
  • Site-wide: 26,380
• Since beginning of last month:
  • Site-wide: 43,631

The Influence of Phenotyping Method on Neuroimaging Associations with Depression in UK Biobank

• Downloaded 150 times
• Download rankings, all-time:
  • Site-wide: 126,728
  • In psychiatry and clinical psychology: 605
• Year to date:
  • Site-wide: 55,360
• Since beginning of last month:
  • Site-wide: 92,397

Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

• Downloaded 131 times
• Download rankings, all-time:
  • Site-wide: 130,625
  • In genetic and genomic medicine: 685
• Year to date:
  • Site-wide: 35,404
• Since beginning of last month:
  • Site-wide: 60,315