Author: David Nemazee

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Preprints

In vivo engineered B cells retain memory and secrete high titers of anti-HIV antibodies in mice

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Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

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Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

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Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

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An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

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Reprogramming the antigen specificity of B cells using genome-editing technologies

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A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

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Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

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Commercial Serology Assays Predict Neutralization Activity Against SARS-CoV-2

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HIV-1 vaccine design through minimizing envelope metastability

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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

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A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

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B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

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Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

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A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

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Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

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SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses

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