Author: David Nemazee

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Preprints

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

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  • Site-wide: 93,899

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

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  • Site-wide: 4,774
  • In immunology: 166
• Year to date:
  • Site-wide: 4,776
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  • Site-wide: 1,343

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

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  • Site-wide: 5,887
  • In immunology: 203
• Year to date:
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Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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  • Site-wide: 6,506
  • In immunology: 221
• Year to date:
  • Site-wide: 16,148
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  • Site-wide: 5,292

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

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  • Site-wide: 11,601
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A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

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  • Site-wide: 14,656
  • In immunology: 481
• Year to date:
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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

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  • Site-wide: 21,124
  • In microbiology: 1,224
• Year to date:
  • Site-wide: 2,844
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  • Site-wide: 79,001

HIV-1 vaccine design through minimizing envelope metastability

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  • Site-wide: 24,898
  • In microbiology: 1,472
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  • Site-wide: 620

Reprogramming the antigen specificity of B cells using genome-editing technologies

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Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

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  • Site-wide: 31,601

Commercial Serology Assays Predict Neutralization Activity Against SARS-CoV-2

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  • Site-wide: 33,288
  • In infectious diseases: 2,512
• Year to date:
  • Site-wide: 24,333
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  • Site-wide: 50,192

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

• Downloaded 728 times
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  • Site-wide: 38,794
  • In immunology: 1,219
• Year to date:
  • Site-wide: 82,929
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  • Site-wide: 61,651

B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

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  • Site-wide: 40,458
  • In immunology: 1,266
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  • Site-wide: 27,591
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  • Site-wide: 12,901

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

• Downloaded 673 times
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  • Site-wide: 43,040
  • In microbiology: 2,611
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  • Site-wide: 127,279

SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses

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  • Site-wide: 45,136
  • In infectious diseases: 2,929
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  • Site-wide: 2,578

In vivo engineered B cells retain memory and secrete high titers of anti-HIV antibodies in mice

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  • Site-wide: 52,393
  • In immunology: 1,595
• Year to date:
  • Site-wide: 7,385
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A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

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  • Site-wide: 57,448
  • In microbiology: 3,636
• Year to date:
  • Site-wide: 8,296
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  • Site-wide: 6,783

Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

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  • Site-wide: 58,263
  • In immunology: 1,768
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  • Site-wide: 66,780

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

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  • Site-wide: 90,216
  • In immunology: 2,677
• Year to date:
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  • Site-wide: 72,578

Broadening a SARS-CoV-1 neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

• Downloaded 323 times
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  • Site-wide: 94,165
  • In bioengineering: 1,801
• Year to date:
  • Site-wide: 17,228
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  • Site-wide: 54,037