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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 73,536 bioRxiv papers from 320,029 authors.

Author: David E Root

  • Most recently observed institution: Broad Institute of Harvard and MIT

Rankings

  • All-time downloads: 28,248 (rank: 856 out of 320,029)
  • Categories:
    • bioinformatics: 653 (rank: 12,925 (tie) out of 27,785)
    • cancer biology: 6,619 (rank: 173 out of 21,127)
    • genomics: 20,976 (rank: 341 out of 35,691)

Downloads per author, site-wide

Preprints

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

genomics more details view paper
  • Downloaded 8,445 times
  • Download rankings, all-time:
    • Site-wide: 194 out of 73,536
    • In genomics: 53 out of 4,879
  • Year to date:
    • Site-wide: 5,953 out of 73,536
  • Since beginning of last month:
    • Site-wide: 5,953 out of 73,536

Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screens

genomics more details view paper
  • Downloaded 6,071 times
  • Download rankings, all-time:
    • Site-wide: 358 out of 73,536
    • In genomics: 88 out of 4,879
  • Year to date:
    • Site-wide: 1,362 out of 73,536
  • Since beginning of last month:
    • Site-wide: 1,362 out of 73,536

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

genomics more details view paper
  • Downloaded 2,608 times
  • Download rankings, all-time:
    • Site-wide: 1,689 out of 73,536
    • In genomics: 369 out of 4,879
  • Year to date:
    • Site-wide: 27,549 out of 73,536
  • Since beginning of last month:
    • Site-wide: 27,549 out of 73,536

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

cancer biology more details view paper
  • Downloaded 2,153 times
  • Download rankings, all-time:
    • Site-wide: 2,400 out of 73,536
    • In cancer biology: 58 out of 2,517
  • Year to date:
    • Site-wide: 3,770 out of 73,536
  • Since beginning of last month:
    • Site-wide: 3,770 out of 73,536

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

genomics more details view paper
  • Downloaded 2,134 times
  • Download rankings, all-time:
    • Site-wide: 2,432 out of 73,536
    • In genomics: 498 out of 4,879
  • Year to date:
    • Site-wide: 15,438 out of 73,536
  • Since beginning of last month:
    • Site-wide: 15,438 out of 73,536

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

cancer biology more details view paper
  • Downloaded 1,760 times
  • Download rankings, all-time:
    • Site-wide: 3,385 out of 73,536
    • In cancer biology: 85 out of 2,517
  • Year to date:
    • Site-wide: 7,956 out of 73,536
  • Since beginning of last month:
    • Site-wide: 7,956 out of 73,536

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

cancer biology more details view paper
  • Downloaded 1,132 times
  • Download rankings, all-time:
    • Site-wide: 7,127 out of 73,536
    • In cancer biology: 194 out of 2,517
  • Year to date:
    • Site-wide: 806 out of 73,536
  • Since beginning of last month:
    • Site-wide: 806 out of 73,536

Mapping protein function with CRISPR/Cas9-mediated mutagenesis

genomics more details view paper
  • Downloaded 1,127 times
  • Download rankings, all-time:
    • Site-wide: 7,176 out of 73,536
    • In genomics: 1,152 out of 4,879
  • Year to date:
    • Site-wide: 42,255 out of 73,536
  • Since beginning of last month:
    • Site-wide: 42,255 out of 73,536

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

cancer biology more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 7,640 out of 73,536
    • In cancer biology: 207 out of 2,517
  • Year to date:
    • Site-wide: 6,240 out of 73,536
  • Since beginning of last month:
    • Site-wide: 6,240 out of 73,536

Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map

bioinformatics more details view paper
  • Downloaded 653 times
  • Download rankings, all-time:
    • Site-wide: 16,708 out of 73,536
    • In bioinformatics: 2,562 out of 7,162
  • Year to date:
    • Site-wide: 65,558 out of 73,536
  • Since beginning of last month:
    • Site-wide: 65,558 out of 73,536

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

cancer biology more details view paper
  • Downloaded 490 times
  • Download rankings, all-time:
    • Site-wide: 24,658 out of 73,536
    • In cancer biology: 767 out of 2,517
  • Year to date:
    • Site-wide: 31,267 out of 73,536
  • Since beginning of last month:
    • Site-wide: 31,267 out of 73,536

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

genomics more details view paper
  • Downloaded 452 times
  • Download rankings, all-time:
    • Site-wide: 27,132 out of 73,536
    • In genomics: 2,829 out of 4,879
  • Year to date:
    • Site-wide: 51,787 out of 73,536
  • Since beginning of last month:
    • Site-wide: 51,787 out of 73,536

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

genomics more details view paper
  • Downloaded 139 times
  • Download rankings, all-time:
    • Site-wide: 64,154 out of 73,536
    • In genomics: 4,599 out of 4,879
  • Year to date:
    • Site-wide: 24,701 out of 73,536
  • Since beginning of last month:
    • Site-wide: 24,701 out of 73,536

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