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Author: Nuria Lopez-Bigas

Rankings

  • All-time downloads: 64,432 (rank: 3,738 )
  • Categories:
    • bioinformatics: 9,160 (rank: 1,446 )
    • cancer biology: 36,452 (rank: 19 )
    • genetics: 686 (rank: 27,137 (tie) )
    • genomics: 14,465 (rank: 1,556 )
    • microbiology: 1,998 (rank: 11,370 (tie) )

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Preprints

Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions

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Copy number footprints of platinum-based anticancer therapies

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The Repertoire of Mutational Signatures in Human Cancer

cancer biology more details view paper
  • Downloaded 20,723 times
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    • Site-wide: 554
    • In cancer biology: 2
  • Year to date:
    • Site-wide: 16,035
  • Since beginning of last month:
    • Site-wide: 8,440

The whole-genome panorama of cancer drivers

cancer biology more details view paper
  • Downloaded 7,487 times
  • Download rankings, all-time:
    • Site-wide: 1,963
    • In cancer biology: 18
  • Year to date:
    • Site-wide: 12,423
  • Since beginning of last month:
    • Site-wide: 7,933

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

genomics more details view paper
  • Downloaded 5,907 times
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    • Site-wide: 2,724
    • In genomics: 208
  • Year to date:
    • Site-wide: 45,893
  • Since beginning of last month:
    • Site-wide: 42,575

A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variants

bioinformatics more details view paper
  • Downloaded 3,718 times
  • Download rankings, all-time:
    • Site-wide: 5,203
    • In bioinformatics: 441
  • Year to date:
    • Site-wide: 82,449
  • Since beginning of last month:
    • Site-wide: 117,410

The mutational footprints of cancer therapies

genomics more details view paper
  • Downloaded 3,181 times
  • Download rankings, all-time:
    • Site-wide: 6,549
    • In genomics: 600
  • Year to date:
    • Site-wide: 80,762
  • Since beginning of last month:
    • Site-wide: 119,520

Cancer Genome Interpreter Annotates The Biological And Clinical Relevance Of Tumor Alterations

cancer biology more details view paper
  • Downloaded 2,560 times
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    • Site-wide: 8,950
    • In cancer biology: 146
  • Year to date:
    • Site-wide: 52,887
  • Since beginning of last month:
    • Site-wide: 42,417

Discovering the drivers of clonal hematopoiesis

genomics more details view paper
  • Downloaded 2,431 times
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    • Site-wide: 9,678
    • In genomics: 907
  • Year to date:
    • Site-wide: 13,583
  • Since beginning of last month:
    • Site-wide: 70,827

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations

bioinformatics more details view paper
  • Downloaded 2,341 times
  • Download rankings, all-time:
    • Site-wide: 10,263
    • In bioinformatics: 1,056
  • Year to date:
    • Site-wide: 74,516
  • Since beginning of last month:
    • Site-wide: 43,446

Nucleotide excision repair is impaired by binding of transcription factors to DNA

genomics more details view paper
  • Downloaded 2,276 times
  • Download rankings, all-time:
    • Site-wide: 10,695
    • In genomics: 968
  • Year to date:
    • Site-wide: 145,115
  • Since beginning of last month:
    • Site-wide: 156,350

In silico saturation mutagenesis of cancer genes

cancer biology more details view paper
  • Downloaded 2,234 times
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    • Site-wide: 10,992
    • In cancer biology: 202
  • Year to date:
    • Site-wide: 31,595
  • Since beginning of last month:
    • Site-wide: 25,493

Mutational dynamics and transmission properties of SARS-CoV-2 superspreading events in Austria

microbiology more details view paper
  • Downloaded 2,024 times
  • Download rankings, all-time:
    • Site-wide: 12,748
    • In microbiology: 734
  • Year to date:
    • Site-wide: 106,913
  • Since beginning of last month:
    • Site-wide: 129,006

Pervasive lesion segregation shapes cancer genome evolution

cancer biology more details view paper
  • Downloaded 1,923 times
  • Download rankings, all-time:
    • Site-wide: 13,809
    • In cancer biology: 259
  • Year to date:
    • Site-wide: 130,088
  • Since beginning of last month:
    • Site-wide: 152,734

The evolution of hematopoietic cells under cancer therapy

cancer biology more details view paper
  • Downloaded 1,189 times
  • Download rankings, all-time:
    • Site-wide: 29,372
    • In cancer biology: 714
  • Year to date:
    • Site-wide: 105,140
  • Since beginning of last month:
    • Site-wide: 132,575

Strand-resolved mutagenicity of DNA damage and repair

genomics more details view paper
  • Downloaded 1,152 times
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    • Site-wide: 30,857
    • In genomics: 3,574
  • Year to date:
    • Site-wide: 2,726
  • Since beginning of last month:
    • Site-wide: 2,104

Disruption of ubiquitin mediated proteolysis is a widespread mechanism of tumorigenesis

bioinformatics more details view paper
  • Downloaded 1,148 times
  • Download rankings, all-time:
    • Site-wide: 31,034
    • In bioinformatics: 3,225
  • Year to date:
    • Site-wide: 111,015
  • Since beginning of last month:
    • Site-wide: 101,835

Bayesian non-parametric clustering of single-cell mutation profiles

bioinformatics more details view paper
  • Downloaded 1,080 times
  • Download rankings, all-time:
    • Site-wide: 34,055
    • In bioinformatics: 3,440
  • Year to date:
    • Site-wide: 171,022
  • Since beginning of last month:
    • Site-wide: None

DeepMP: a deep learning tool to detect DNA base modifications on Nanopore sequencing data

bioinformatics more details view paper
  • Downloaded 1,022 times
  • Download rankings, all-time:
    • Site-wide: 37,065
    • In bioinformatics: 3,860
  • Year to date:
    • Site-wide: 68,675
  • Since beginning of last month:
    • Site-wide: 57,314

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

cancer biology more details view paper
  • Downloaded 852 times
  • Download rankings, all-time:
    • Site-wide: 48,911
    • In cancer biology: 1,554
  • Year to date:
    • Site-wide: 15,097
  • Since beginning of last month:
    • Site-wide: 13,215

Germline loss-of-function variants in the base-excision repair gene MBD4 cause a Mendelian recessive syndrome of adenomatous colorectal polyposis and acute myeloid leukaemia

genetics more details view paper
  • Downloaded 737 times
  • Download rankings, all-time:
    • Site-wide: 60,604
    • In genetics: 2,471
  • Year to date:
    • Site-wide: 26,372
  • Since beginning of last month:
    • Site-wide: 27,956

Signatures 1 and 17 show increased propensity to create mutational hotspots in the human genome

genomics more details view paper
  • Downloaded 447 times
  • Download rankings, all-time:
    • Site-wide: 112,579
    • In genomics: None
  • Year to date:
    • Site-wide: 12,842
  • Since beginning of last month:
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