Author: Mihai G. Netea

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Preprints

The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses

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  • Site-wide: 141
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  • Site-wide: 31
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  • Site-wide: 16

The effect of influenza vaccination on trained immunity: impact on COVID-19

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  • Site-wide: 950
  • In infectious diseases: 296
• Year to date:
  • Site-wide: 1,480
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  • Site-wide: 53,109

COVID-19: A model correlating BCG vaccination to protection from mortality implicates trained immunity

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  • Site-wide: 2,490
  • In infectious diseases: 591
• Year to date:
  • Site-wide: 13,119
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  • Site-wide: 96,610

Genomics of Mesolithic Scandinavia reveal colonization routes and high-latitude adaptation

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  • Site-wide: 3,043
  • In genomics: 306
• Year to date:
  • Site-wide: 32,558
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  • Site-wide: None

Hydroxychloroquine inhibits trained immunity - implications for COVID-19

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  • Site-wide: 4,135
  • In allergy and immunology: 28
• Year to date:
  • Site-wide: 13,927
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  • Site-wide: 25,432

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

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  • Site-wide: 4,406
  • In infectious diseases: 845
• Year to date:
  • Site-wide: 9,924
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  • Site-wide: 88,424

ACTIVATE-2: A DOUBLE-BLIND RANDOMIZED TRIAL OF BCG VACCINATION AGAINST COVID19 IN INDIVIDUALS AT RISK

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  • In infectious diseases: 1,056
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  • Site-wide: 282

Early Anakinra Treatment for COVID-19 Guided by Urokinase Plasminogen Receptor

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  • In infectious diseases: 1,339
• Year to date:
  • Site-wide: 1,411
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  • Site-wide: 1,075

Swarm Learning as a privacy-preserving machine learning approach for disease classification

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  • Site-wide: 9,875
  • In bioinformatics: 1,139
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  • Site-wide: 6,407
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  • Site-wide: 85,083

A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection

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  • Site-wide: 10,792
  • In infectious diseases: 1,446
• Year to date:
  • Site-wide: 24,779
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  • Site-wide: 52,646

Comparative analysis of neutrophil and monocyte epigenomes

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  • Site-wide: 12,274
  • In genomics: 1,256
• Year to date:
  • Site-wide: 32,839
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  • Site-wide: 120,877

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

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  • Site-wide: 15,474
  • In genomics: 1,539
• Year to date:
  • Site-wide: 127,532
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  • Site-wide: 112,115

Heme induces innate immunity memory

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  • Site-wide: 18,734
  • In immunology: 632
• Year to date:
  • Site-wide: 22,995
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  • Site-wide: 12,333

Anakinra To Prevent Respiratory Failure In COVID-19

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  • Site-wide: 22,225
  • In infectious diseases: 2,024
• Year to date:
  • Site-wide: 10,746
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  • Site-wide: 101,333

Increased plasma heparanase activity in COVID-19 patients

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  • Site-wide: 23,228
  • In infectious diseases: 2,061
• Year to date:
  • Site-wide: 63,249
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  • Site-wide: 97,628

COVID-19 as cause of viral sepsis: A Systematic Review and Meta-Analysis

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  • Site-wide: 48,806
  • In infectious diseases: 3,054
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  • Site-wide: 11,891
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  • Site-wide: 5,549

Impact of rare and common genetic variation in the Interleukin-1 pathway for human cytokine responses

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  • Site-wide: 53,047
  • In systems biology: 1,177
• Year to date:
  • Site-wide: 53,566
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  • Site-wide: 44,314

ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically Ill COVID-19 Patients

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  • Site-wide: 55,311
  • In intensive care and critical care medicine: 154
• Year to date:
  • Site-wide: 8,059
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  • Site-wide: 54,378

Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes

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  • Site-wide: 60,353
  • In infectious diseases: 3,366
• Year to date:
  • Site-wide: 31,356
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  • Site-wide: 35,600

Effect of anakinra on mortality in COVID-19: a patient level meta-analysis

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  • Site-wide: 65,968
  • In infectious diseases: 3,529
• Year to date:
  • Site-wide: 10,115
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  • Site-wide: None

Gut microbial structural variations as determinants of human bile acid metabolism

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  • Site-wide: 68,589
  • In microbiology: 4,502
• Year to date:
  • Site-wide: 10,642
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  • Site-wide: 7,600

The right microbial stimulus can direct innate immune effector cells to specific organ sites to clear pathology

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  • Site-wide: 73,448
  • In immunology: 2,207
• Year to date:
  • Site-wide: 106,350
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  • Site-wide: 38,832

The genetic risk for COVID-19 severity is associated with defective innate immune responses

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  • Site-wide: 75,655
  • In genetic and genomic medicine: 326
• Year to date:
  • Site-wide: 28,231
• Since beginning of last month:
  • Site-wide: 88,638

Persistent DNA Hyper-methylation Dampens Host Anti-Mycobacterial Immunity

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  • Site-wide: 76,201
  • In immunology: 2,278
• Year to date:
  • Site-wide: 116,510
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  • Site-wide: 72,460

Clone expansion of mutation-driven clonal hematopoiesis is associated with aging and metabolic dysfunction in individuals with obesity

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  • Site-wide: 78,081
  • In genomics: 5,196
• Year to date:
  • Site-wide: 12,755
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  • Site-wide: 22,322

Evolution of cytokine production capacity in ancient and modern European populations

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  • Site-wide: 112,826
  • In genomics: 6,478
• Year to date:
  • Site-wide: 25,577
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  • Site-wide: 84,067

IL-1 Mediates Tissue Specific Inflammation and Severe Respiratory Failure In Covid-19: Clinical And Experimental Evidence

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  • Site-wide: 120,878
  • In infectious diseases: 4,943
• Year to date:
  • Site-wide: 30,435
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  • Site-wide: 104,305

Lung epithelial signaling mediates early vaccine-induced CD4+ T cell activation and Mtb control

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  • Site-wide: 124,140
  • In immunology: 3,682
• Year to date:
  • Site-wide: 32,925
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  • Site-wide: 30,516

Discovery, diversity and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts

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  • Site-wide: 124,153
  • In microbiology: 9,162
• Year to date:
  • Site-wide: 32,909
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  • Site-wide: 76,608

A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis

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  • Site-wide: 146,423
  • In infectious diseases: 5,754
• Year to date:
  • Site-wide: 69,293
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  • Site-wide: 14,680