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Author: Sekar Kathiresan

  • ORCiD: http://orcid.org/0000-0002-6724-032X
  • Most recently observed institution: Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA, 02114.

Rankings

  • All-time downloads: 86,616 (rank: 1,924 )
  • Categories:
    • bioinformatics: 2,499 (rank: 6,578 (tie) )
    • cardiovascular medicine: 895 (rank: 688 (tie) )
    • genetic and genomic medicine: 9,697 (rank: 102 )
    • genetics: 17,614 (rank: 833 )
    • genomics: 54,135 (rank: 182 )
    • hiv aids: 1,776 (rank: 61 (tie) )

Downloads per author, site-wide

Preprints

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
  • Downloaded 22,187 times
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    • Site-wide: 392
    • In genomics: 13
  • Year to date:
    • Site-wide: 28,943
  • Since beginning of last month:
    • Site-wide: 53,264

An open resource of structural variation for medical and population genetics

genomics more details view paper
  • Downloaded 11,252 times
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    • Site-wide: 896
    • In genomics: 62
  • Year to date:
    • Site-wide: 12,371
  • Since beginning of last month:
    • Site-wide: 33,556

Polygenic background modifies penetrance of monogenic variants conferring risk for coronary artery disease, breast cancer, or colorectal cancer

genetic and genomic medicine more details view paper
  • Downloaded 7,970 times
  • Download rankings, all-time:
    • Site-wide: 1,382
    • In genetic and genomic medicine: 6
  • Year to date:
    • Site-wide: 23,199
  • Since beginning of last month:
    • Site-wide: 35,517

Genome-wide polygenic score to identify a monogenic risk-equivalent for coronary disease

genomics more details view paper
  • Downloaded 4,998 times
  • Download rankings, all-time:
    • Site-wide: 2,563
    • In genomics: 241
  • Year to date:
    • Site-wide: 47,258
  • Since beginning of last month:
    • Site-wide: 46,544

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,252 times
  • Download rankings, all-time:
    • Site-wide: 4,657
    • In genetics: 176
  • Year to date:
    • Site-wide: 39,603
  • Since beginning of last month:
    • Site-wide: 52,954

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 3,188 times
  • Download rankings, all-time:
    • Site-wide: 4,785
    • In genomics: 485
  • Year to date:
    • Site-wide: 10,358
  • Since beginning of last month:
    • Site-wide: 16,281

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

genetics more details view paper
  • Downloaded 2,655 times
  • Download rankings, all-time:
    • Site-wide: 6,217
    • In genetics: 257
  • Year to date:
    • Site-wide: 24,062
  • Since beginning of last month:
    • Site-wide: 29,149

Non-parametric polygenic risk prediction using partitioned GWAS summary statistics

bioinformatics more details view paper
  • Downloaded 2,499 times
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    • Site-wide: 6,832
    • In bioinformatics: 724
  • Year to date:
    • Site-wide: 87,346
  • Since beginning of last month:
    • Site-wide: 147,937

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

genomics more details view paper
  • Downloaded 2,459 times
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    • Site-wide: 6,987
    • In genomics: 728
  • Year to date:
    • Site-wide: 68,489
  • Since beginning of last month:
    • Site-wide: 38,863

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

genetics more details view paper
  • Downloaded 2,352 times
  • Download rankings, all-time:
    • Site-wide: 7,441
    • In genetics: 319
  • Year to date:
    • Site-wide: 5,013
  • Since beginning of last month:
    • Site-wide: 7,784

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

genetics more details view paper
  • Downloaded 2,351 times
  • Download rankings, all-time:
    • Site-wide: 7,444
    • In genetics: 320
  • Year to date:
    • Site-wide: 115,011
  • Since beginning of last month:
    • Site-wide: 100,499

Biological and clinical insights from genetics of insomnia symptoms

genomics more details view paper
  • Downloaded 2,280 times
  • Download rankings, all-time:
    • Site-wide: 7,813
    • In genomics: 798
  • Year to date:
    • Site-wide: 12,908
  • Since beginning of last month:
    • Site-wide: 18,234

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

genomics more details view paper
  • Downloaded 2,118 times
  • Download rankings, all-time:
    • Site-wide: 8,673
    • In genomics: 870
  • Year to date:
    • Site-wide: 149,512
  • Since beginning of last month:
    • Site-wide: 148,933

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,899 times
  • Download rankings, all-time:
    • Site-wide: 10,163
    • In genetics: 432
  • Year to date:
    • Site-wide: 110,000
  • Since beginning of last month:
    • Site-wide: 110,248

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 1,776 times
  • Download rankings, all-time:
    • Site-wide: 11,241
    • In hiv aids: 6
  • Year to date:
    • Site-wide: 5,069
  • Since beginning of last month:
    • Site-wide: 5,454

Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores

genomics more details view paper
  • Downloaded 1,511 times
  • Download rankings, all-time:
    • Site-wide: 14,239
    • In genomics: 1,421
  • Year to date:
    • Site-wide: 45,934
  • Since beginning of last month:
    • Site-wide: 56,804

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.

genetic and genomic medicine more details view paper
  • Downloaded 1,427 times
  • Download rankings, all-time:
    • Site-wide: 15,610
    • In genetic and genomic medicine: 71
  • Year to date:
    • Site-wide: 2,629
  • Since beginning of last month:
    • Site-wide: 2,868

Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology

genetics more details view paper
  • Downloaded 1,355 times
  • Download rankings, all-time:
    • Site-wide: 16,879
    • In genetics: 758
  • Year to date:
    • Site-wide: 38,042
  • Since beginning of last month:
    • Site-wide: 47,679

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

genetics more details view paper
  • Downloaded 1,191 times
  • Download rankings, all-time:
    • Site-wide: 20,453
    • In genetics: 918
  • Year to date:
    • Site-wide: 4,959
  • Since beginning of last month:
    • Site-wide: 1,907

Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy

genomics more details view paper
  • Downloaded 906 times
  • Download rankings, all-time:
    • Site-wide: 30,529
    • In genomics: 2,654
  • Year to date:
    • Site-wide: 65,981
  • Since beginning of last month:
    • Site-wide: 58,255

Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failure

cardiovascular medicine more details view paper
  • Downloaded 895 times
  • Download rankings, all-time:
    • Site-wide: 31,037
    • In cardiovascular medicine: 51
  • Year to date:
    • Site-wide: 75,212
  • Since beginning of last month:
    • Site-wide: 122,605

South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity – New Resources for Precision Medicine

genomics more details view paper
  • Downloaded 888 times
  • Download rankings, all-time:
    • Site-wide: 31,432
    • In genomics: 2,709
  • Year to date:
    • Site-wide: 25,576
  • Since beginning of last month:
    • Site-wide: 41,847

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 877 times
  • Download rankings, all-time:
    • Site-wide: 32,008
    • In genetics: 1,436
  • Year to date:
    • Site-wide: 94,300
  • Since beginning of last month:
    • Site-wide: 107,744

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

genomics more details view paper
  • Downloaded 806 times
  • Download rankings, all-time:
    • Site-wide: 36,038
    • In genomics: 3,002
  • Year to date:
    • Site-wide: 93,099
  • Since beginning of last month:
    • Site-wide: 93,710

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 788 times
  • Download rankings, all-time:
    • Site-wide: 37,233
    • In genomics: 3,072
  • Year to date:
    • Site-wide: 124,325
  • Since beginning of last month:
    • Site-wide: 135,545

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

genetics more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 37,615
    • In genetics: 1,666
  • Year to date:
    • Site-wide: 153,342
  • Since beginning of last month:
    • Site-wide: 143,154

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 754 times
  • Download rankings, all-time:
    • Site-wide: 39,673
    • In genomics: 3,213
  • Year to date:
    • Site-wide: 155,589
  • Since beginning of last month:
    • Site-wide: 156,239

Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease

genetics more details view paper
  • Downloaded 470 times
  • Download rankings, all-time:
    • Site-wide: 71,296
    • In genetics: 3,083
  • Year to date:
    • Site-wide: 99,930
  • Since beginning of last month:
    • Site-wide: 72,622

EDEM3 modulates plasma triglyceride level through its regulation of LRP1 expression

genetics more details view paper
  • Downloaded 430 times
  • Download rankings, all-time:
    • Site-wide: 78,302
    • In genetics: 3,360
  • Year to date:
    • Site-wide: 127,012
  • Since beginning of last month:
    • Site-wide: 90,653

Prospective evaluation of genome sequencing versus standard-of-care as a first molecular diagnostic test

genetic and genomic medicine more details view paper
  • Downloaded 300 times
  • Download rankings, all-time:
    • Site-wide: 106,581
    • In genetic and genomic medicine: 555
  • Year to date:
    • Site-wide: 54,356
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    • Site-wide: 26,679

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