Author: Zhe Zhang

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Preprints

Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial

• Downloaded 10,539 times
• Download rankings, all-time:
  • Site-wide: 889
  • In infectious diseases: 279
• Year to date:
  • Site-wide: 5,081
• Since beginning of last month:
  • Site-wide: 14,728

A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability

• Downloaded 4,340 times
• Download rankings, all-time:
  • Site-wide: 2,875
  • In biochemistry: 44
• Year to date:
  • Site-wide: 7,670
• Since beginning of last month:
  • Site-wide: 24,729

RNA-Seq 2G: Online Analysis Of Differential Gene Expression With Comprehensive Options Of Statistical Methods

• Downloaded 2,986 times
• Download rankings, all-time:
  • Site-wide: 4,856
  • In bioinformatics: 479
• Year to date:
  • Site-wide: 11,968
• Since beginning of last month:
  • Site-wide: 741

SARS-CoV-2 manipulates the SR-B1-mediated HDL uptake pathway for its entry

• Downloaded 2,310 times
• Download rankings, all-time:
  • Site-wide: 7,079
  • In microbiology: 430
• Year to date:
  • Site-wide: 1,832
• Since beginning of last month:
  • Site-wide: 52,952

The Chronic Kidney Disease and Acute Kidney Injury Involvement in COVID-19 Pandemic: A Systematic Review and Meta-analysis

• Downloaded 1,006 times
• Download rankings, all-time:
  • Site-wide: 24,193
  • In nephrology: 13
• Year to date:
  • Site-wide: 30,519
• Since beginning of last month:
  • Site-wide: 99,073

Generating Templates and Growth Charts for School-Aged Brain Development

• Downloaded 889 times
• Download rankings, all-time:
  • Site-wide: 28,878
  • In neuroscience: 3,766
• Year to date:
  • Site-wide: 67,571
• Since beginning of last month:
  • Site-wide: 60,015

Age-dependent sexual dimorphism in the adult human gut microbiota

• Downloaded 801 times
• Download rankings, all-time:
  • Site-wide: 33,414
  • In genomics: 2,870
• Year to date:
  • Site-wide: 84,513
• Since beginning of last month:
  • Site-wide: 57,574

An Array of 60,000 Antibodies for Proteome-Scale Antibody Generation and Target Discovery

• Downloaded 785 times
• Download rankings, all-time:
  • Site-wide: 34,408
  • In systems biology: 728
• Year to date:
  • Site-wide: 109,903
• Since beginning of last month:
  • Site-wide: None

Tertiary Lymphoid Structure and CD8 T Cell Exclusion in Minimally Invasive Adenocarcinoma

• Downloaded 726 times
• Download rankings, all-time:
  • Site-wide: 38,298
  • In genetic and genomic medicine: 151
• Year to date:
  • Site-wide: 15,418
• Since beginning of last month:
  • Site-wide: 33,730

Genome sequencing analysis identifies high-risk Epstein-Barr virus subtypes for nasopharyngeal carcinoma

• Downloaded 599 times
• Download rankings, all-time:
  • Site-wide: 49,068
  • In genetics: 2,176
• Year to date:
  • Site-wide: 71,454
• Since beginning of last month:
  • Site-wide: None

ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression

• Downloaded 598 times
• Download rankings, all-time:
  • Site-wide: 49,240
  • In molecular biology: 1,392
• Year to date:
  • Site-wide: 41,008
• Since beginning of last month:
  • Site-wide: 115,453

NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data

• Downloaded 595 times
• Download rankings, all-time:
  • Site-wide: 49,564
  • In bioinformatics: 5,102
• Year to date:
  • Site-wide: 16,541
• Since beginning of last month:
  • Site-wide: 48,362

An effective, safe and cost-effective cell-based chimeric vaccine against SARS-CoV2

• Downloaded 556 times
• Download rankings, all-time:
  • Site-wide: 53,987
  • In immunology: 1,618
• Year to date:
  • Site-wide: 53,127
• Since beginning of last month:
  • Site-wide: 52,602

The female urinary microbiota in relation to the reproductive tract microbiota

• Downloaded 548 times
• Download rankings, all-time:
  • Site-wide: 54,879
  • In microbiology: 3,506
• Year to date:
  • Site-wide: 50,765
• Since beginning of last month:
  • Site-wide: 13,648

A novel viral protein translation mechanism reveals mitochondria as a target for antiviral drug development

• Downloaded 484 times
• Download rankings, all-time:
  • Site-wide: 63,320
  • In microbiology: 4,145
• Year to date:
  • Site-wide: 37,072
• Since beginning of last month:
  • Site-wide: 114,983

Sub-species niche specialization in the oral microbiome is associated with nasopharyngeal carcinoma risk

• Downloaded 472 times
• Download rankings, all-time:
  • Site-wide: 65,161
  • In microbiology: 4,298
• Year to date:
  • Site-wide: 74,091
• Since beginning of last month:
  • Site-wide: 40,073

The conserved ER-transmembrane protein TMEM39 coordinates with COPII to promote collagen secretion and prevent ER stress

• Downloaded 471 times
• Download rankings, all-time:
  • Site-wide: 65,197
  • In cell biology: 2,859
• Year to date:
  • Site-wide: 52,509
• Since beginning of last month:
  • Site-wide: None

GSA-Genie: a web application for gene set analysis

• Downloaded 399 times
• Download rankings, all-time:
  • Site-wide: 77,200
  • In bioinformatics: 7,186
• Year to date:
  • Site-wide: 119,961
• Since beginning of last month:
  • Site-wide: None

Inter-determination of blood metabolite levels and gut microbiome supported by Mendelian randomization

• Downloaded 380 times
• Download rankings, all-time:
  • Site-wide: 80,682
  • In genetics: 3,529
• Year to date:
  • Site-wide: 47,039
• Since beginning of last month:
  • Site-wide: 46,856

Broadly Conserved Roles of TMEM-131 Family Proteins in Intracellular Collagen Assembly and Secretory Cargo Trafficking

• Downloaded 367 times
• Download rankings, all-time:
  • Site-wide: 83,215
  • In cell biology: 3,807
• Year to date:
  • Site-wide: 116,915
• Since beginning of last month:
  • Site-wide: 40,001

Accurate inference of the full base-pairing structure of RNA by deep mutational scanning and covariation-induced deviation of activity

• Downloaded 360 times
• Download rankings, all-time:
  • Site-wide: 84,710
  • In molecular biology: 2,468
• Year to date:
  • Site-wide: 141,891
• Since beginning of last month:
  • Site-wide: None

Changes of the Commensal Microbiome during Treatment are Associated with Clinical Response in Nasopharyngeal Carcinoma Patients

• Downloaded 341 times
• Download rankings, all-time:
  • Site-wide: 88,521
  • In oncology: 157
• Year to date:
  • Site-wide: 101,044
• Since beginning of last month:
  • Site-wide: 107,506

High-quality genome assembly and high-density genetic map of asparagus bean

• Downloaded 318 times
• Download rankings, all-time:
  • Site-wide: 93,614
  • In genomics: 5,821
• Year to date:
  • Site-wide: 142,851
• Since beginning of last month:
  • Site-wide: None

Resurrecting self-cleaving mini-ribozymes from 40-million-year-old LINE-1 elements in human genome

• Downloaded 195 times
• Download rankings, all-time:
  • Site-wide: 123,206
  • In molecular biology: 3,636
• Year to date:
  • Site-wide: 31,106
• Since beginning of last month:
  • Site-wide: 50,945

PHARP: A pig haplotype reference panel for genotype imputation

• Downloaded 185 times
• Download rankings, all-time:
  • Site-wide: 125,699
  • In genomics: 6,866
• Year to date:
  • Site-wide: 33,155
• Since beginning of last month:
  • Site-wide: 28,139

FMRP regulates experience-dependent maturation of callosal synaptic connections and bilateral cortical synchrony

• Downloaded 94 times
• Download rankings, all-time:
  • Site-wide: 144,781
  • In neuroscience: 21,905
• Year to date:
  • Site-wide: 66,896
• Since beginning of last month:
  • Site-wide: None

KIF2C regulates synaptic plasticity and cognition by mediating dynamic microtubule invasion of dendritic spines

• Downloaded 45 times
• Download rankings, all-time:
  • Site-wide: 150,563
  • In neuroscience: 22,716
• Year to date:
  • Site-wide: 113,923
• Since beginning of last month:
  • Site-wide: 1,150