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Author: Alessandro Sette

  • ORCiD: http://orcid.org/0000-0001-7013-2250
  • Most recently observed institution: Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, CA 92037

Rankings

  • All-time downloads: 309,864 (rank: 185 )
  • Categories:
    • allergy and immunology: 7,935 (rank: 353 )
    • bioinformatics: 993 (rank: 22,673 (tie) )
    • hiv aids: 1,140 (rank: 305 )
    • immunology: 205,928 (rank: 1 )
    • infectious diseases: 86,106 (rank: 859 )
    • microbiology: 2,904 (rank: 8,197 (tie) )
    • neurology: 1,788 (rank: 1,491 (tie) )
    • neuroscience: 488 (rank: 74,248 (tie) )
    • systems biology: 383 (rank: 14,915 (tie) )

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Preprints

Long-term respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination

immunology more details view paper

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Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life

infectious diseases more details view paper

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Immunological memory to SARS-CoV-2 assessed for up to eight months after infection

immunology more details view paper
  • Downloaded 73,308 times
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    • Site-wide: 124
    • In immunology: 4
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    • Site-wide: 1,699
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    • Site-wide: 2,259

mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

immunology more details view paper
  • Downloaded 39,085 times
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    • Site-wide: 259
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    • Site-wide: 5,230
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Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees.

immunology more details view paper
  • Downloaded 30,144 times
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    • Site-wide: 356
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    • Site-wide: 4,691
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SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

infectious diseases more details view paper
  • Downloaded 25,827 times
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Humoral and cellular immune memory to four COVID-19 vaccines

immunology more details view paper
  • Downloaded 14,665 times
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Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome

infectious diseases more details view paper
  • Downloaded 10,906 times
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Divergent SARS CoV-2 Omicron-specific T- and B-cell responses in COVID-19 vaccine recipients

infectious diseases more details view paper
  • Downloaded 10,279 times
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Low dose mRNA-1273 COVID-19 vaccine generates durable T cell memory and antibodies enhanced by pre-existing crossreactive T cell memory

infectious diseases more details view paper
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Interim Report: Safety And Immunogenicity Of An Inactivated Vaccine Against Sars-Cov-2 In Healthy Chilean Adults In A Phase 3 Clinical Trial

infectious diseases more details view paper
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SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron

immunology more details view paper
  • Downloaded 7,452 times
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    • Site-wide: 2,018
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Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination

immunology more details view paper
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    • Site-wide: 3,078
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Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions

immunology more details view paper
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Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4+ T cells

immunology more details view paper
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Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines

immunology more details view paper
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    • Site-wide: 4,971
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A booster dose of an inactivated SARS-CoV-2 vaccine increases neutralizing antibodies and T cells that recognize Delta and Omicron variants of concern

infectious diseases more details view paper
  • Downloaded 3,596 times
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    • Site-wide: 5,604
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T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

infectious diseases more details view paper
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The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

infectious diseases more details view paper
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COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection

infectious diseases more details view paper
  • Downloaded 3,280 times
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Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

immunology more details view paper
  • Downloaded 3,143 times
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Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level

microbiology more details view paper
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Omicron-specific cytotoxic T-cell responses are boosted following a third dose of mRNA COVID-19 vaccine in anti-CD20-treated multiple sclerosis patients

allergy and immunology more details view paper
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Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

allergy and immunology more details view paper
  • Downloaded 2,297 times
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Altered cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.

neurology more details view paper
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Distinguishing COVID-19 infection and vaccination history by T cell reactivity

immunology more details view paper
  • Downloaded 1,757 times
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SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

immunology more details view paper
  • Downloaded 1,644 times
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Durable protection against SARS-CoV-2 Omicron induced by an adjuvanted subunit vaccine

immunology more details view paper
  • Downloaded 1,610 times
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    • Site-wide: 18,864
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    • Site-wide: 17,399
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Immune memory in mild COVID-19 patients and unexposed donors from India reveals persistent T cell responses after SARS-CoV-2 infection

infectious diseases more details view paper
  • Downloaded 1,385 times
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    • Site-wide: 24,024
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    • Site-wide: 53,159
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    • Site-wide: 54,914

An inactivated SARS-CoV-2 vaccine is safe and induces humoral and cellular immunity against virus variants in healthy children and adolescents in Chile

infectious diseases more details view paper
  • Downloaded 1,298 times
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Differential T cell reactivity to seasonal coronaviruses and SARS-CoV-2 in community and health care workers

infectious diseases more details view paper
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Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant dependent manner

infectious diseases more details view paper
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Inactivated virus vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

infectious diseases more details view paper
  • Downloaded 1,194 times
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Patients treated with anti-CD20 therapy can mount robust T cell responses to mRNA-based COVID-19 vaccines

allergy and immunology more details view paper
  • Downloaded 1,169 times
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Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

immunology more details view paper
  • Downloaded 1,148 times
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POST-ACUTE SEQUELAE AND ADAPTIVE IMMUNE RESPONSES IN PEOPLE LIVING WITH HIV RECOVERING FROM SARS-COV-2 INFECTION

hiv aids more details view paper
  • Downloaded 1,054 times
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No cell is an island: circulating T cell:monocyte complexes are markers of immune perturbations

immunology more details view paper
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A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

immunology more details view paper
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NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses

immunology more details view paper
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Antigen-specific induction of CD4+CD8αα+ intraepithelial T lymphocytes by Bacteroidetes species

immunology more details view paper
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Benchmarking predictions of MHC class I restricted T cell epitopes

immunology more details view paper
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Profile of SARS-CoV-2-specific CD4 T cell response: Relationship with disease severity and impact of HIV-1 and active Mycobacterium tuberculosis co-infection

infectious diseases more details view paper
  • Downloaded 857 times
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Footprints of antigen processing boost MHC class II natural ligand binding predictions

immunology more details view paper
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PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

immunology more details view paper
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Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period

immunology more details view paper
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Humoral and cellular immune responses to CoronaVac assessed up to one year after vaccination

allergy and immunology more details view paper
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Immuno-proteomic interrogation of dengue infection reveals novel HLA haplotype-specific MHC-I antigens

immunology more details view paper
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The challenge of distinguishing cell-cell complexes from singlet cells in non-imaging flow cytometry and single-cell sorting

immunology more details view paper
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Dichotomy between the humoral and cellular responses elicited by mRNA and adenoviral vector vaccines against SARS-CoV-2.

infectious diseases more details view paper
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Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination

immunology more details view paper
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DAFi: A Directed Recursive Filtering and Clustering Approach to Data-Driven Identification of Cell Populations from Polychromatic Flow Cytometry Data

bioinformatics more details view paper
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Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

immunology more details view paper
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Durability of immune responses to the booster mRNA vaccination against COVID-19

allergy and immunology more details view paper
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TCRMatch: Predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors

immunology more details view paper
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A highly efficient T-cell immunoassay provides assessment of B cell help function of SARS-CoV-2 specific memory CD4+ T cells

allergy and immunology more details view paper
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Interaction of an α-synuclein epitope with HLA-DRB1*15:01 initiates early enteric features of Parkinson's disease in humanized mice

neuroscience more details view paper
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Ad26.COV2.S priming provides a solid immunological base for mRNA-based COVID-19 booster vaccination

infectious diseases more details view paper
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Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

immunology more details view paper
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CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

immunology more details view paper
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Profiling Human CMV-specific T cell responses reveals novel immunogenic ORFs

immunology more details view paper
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Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures

immunology more details view paper
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T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species.

immunology more details view paper
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A system-view of B. pertussis booster vaccine responses in adults primed with whole-cell vs. acellular vaccine in infancy

systems biology more details view paper
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Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults

infectious diseases more details view paper
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Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

immunology more details view paper
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Combined assessment of MHC binding and antigen expression improves T cell epitope predictions

bioinformatics more details view paper
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Antigenic determinants of SARS-CoV-2-specific CD4+ T cell lines reveals M protein-driven dysregulation of interferon signaling

infectious diseases more details view paper
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Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response

immunology more details view paper
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IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

immunology more details view paper
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Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA-DQ2.5

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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

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Peripheral blood T-cell deficiency and hyperinflammatory monocyte responses associate with MAC lung disease

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Differential immune response induced by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial

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Profile of Mycobacterium tuberculosis-specific CD4 T cells at the site of disease and blood in pericardial tuberculosis

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Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile

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Design and validation of HIV peptide pools for detection of HIV-specific CD4+ and CD8+ T cells

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Upregulation of Activation Induced Cell Markers (AIM) among Severe COVID-19 patients in Bangladesh

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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response

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