Author: Alessandro Sette

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Preprints

Long-term respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination

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Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life

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Immunological memory to SARS-CoV-2 assessed for up to eight months after infection

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mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

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Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees.

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SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

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Humoral and cellular immune memory to four COVID-19 vaccines

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Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome

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Divergent SARS CoV-2 Omicron-specific T- and B-cell responses in COVID-19 vaccine recipients

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  • Site-wide: 6,317
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  • Site-wide: 7,788

Low dose mRNA-1273 COVID-19 vaccine generates durable T cell memory and antibodies enhanced by pre-existing crossreactive T cell memory

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Interim Report: Safety And Immunogenicity Of An Inactivated Vaccine Against Sars-Cov-2 In Healthy Chilean Adults In A Phase 3 Clinical Trial

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SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron

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Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination

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Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions

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Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4+ T cells

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Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines

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A booster dose of an inactivated SARS-CoV-2 vaccine increases neutralizing antibodies and T cells that recognize Delta and Omicron variants of concern

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T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

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The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

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COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection

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Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

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Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level

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Omicron-specific cytotoxic T-cell responses are boosted following a third dose of mRNA COVID-19 vaccine in anti-CD20-treated multiple sclerosis patients

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Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

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Altered cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.

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Distinguishing COVID-19 infection and vaccination history by T cell reactivity

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  • Site-wide: 32,916
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SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

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Durable protection against SARS-CoV-2 Omicron induced by an adjuvanted subunit vaccine

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Immune memory in mild COVID-19 patients and unexposed donors from India reveals persistent T cell responses after SARS-CoV-2 infection

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An inactivated SARS-CoV-2 vaccine is safe and induces humoral and cellular immunity against virus variants in healthy children and adolescents in Chile

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  • Site-wide: 26,659
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Differential T cell reactivity to seasonal coronaviruses and SARS-CoV-2 in community and health care workers

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  • Site-wide: 28,156

Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant dependent manner

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Inactivated virus vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

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Patients treated with anti-CD20 therapy can mount robust T cell responses to mRNA-based COVID-19 vaccines

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Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

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POST-ACUTE SEQUELAE AND ADAPTIVE IMMUNE RESPONSES IN PEOPLE LIVING WITH HIV RECOVERING FROM SARS-COV-2 INFECTION

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No cell is an island: circulating T cell:monocyte complexes are markers of immune perturbations

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A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

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NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses

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Antigen-specific induction of CD4+CD8αα+ intraepithelial T lymphocytes by Bacteroidetes species

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Benchmarking predictions of MHC class I restricted T cell epitopes

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Profile of SARS-CoV-2-specific CD4 T cell response: Relationship with disease severity and impact of HIV-1 and active Mycobacterium tuberculosis co-infection

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Footprints of antigen processing boost MHC class II natural ligand binding predictions

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PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

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Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period

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Humoral and cellular immune responses to CoronaVac assessed up to one year after vaccination

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Immuno-proteomic interrogation of dengue infection reveals novel HLA haplotype-specific MHC-I antigens

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The challenge of distinguishing cell-cell complexes from singlet cells in non-imaging flow cytometry and single-cell sorting

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Dichotomy between the humoral and cellular responses elicited by mRNA and adenoviral vector vaccines against SARS-CoV-2.

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Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination

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DAFi: A Directed Recursive Filtering and Clustering Approach to Data-Driven Identification of Cell Populations from Polychromatic Flow Cytometry Data

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Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

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Durability of immune responses to the booster mRNA vaccination against COVID-19

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TCRMatch: Predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors

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A highly efficient T-cell immunoassay provides assessment of B cell help function of SARS-CoV-2 specific memory CD4+ T cells

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Interaction of an α-synuclein epitope with HLA-DRB1*15:01 initiates early enteric features of Parkinson's disease in humanized mice

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Ad26.COV2.S priming provides a solid immunological base for mRNA-based COVID-19 booster vaccination

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Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

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CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

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Profiling Human CMV-specific T cell responses reveals novel immunogenic ORFs

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Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures

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T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species.

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A system-view of B. pertussis booster vaccine responses in adults primed with whole-cell vs. acellular vaccine in infancy

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Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults

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Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

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Combined assessment of MHC binding and antigen expression improves T cell epitope predictions

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Antigenic determinants of SARS-CoV-2-specific CD4+ T cell lines reveals M protein-driven dysregulation of interferon signaling

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Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response

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IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

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Unaltered T cell responses to common antigens in individuals with Parkinson's disease

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Transcriptomics of acute DENV-specific CD8+ T cells does not support qualitative differences as drivers of disease severity.

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Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA-DQ2.5

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Evaluation of the CD4+ T cell response to SARS-CoV-2 infection and cross reactivity to beta variant in children of all ages

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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

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Peripheral blood T-cell deficiency and hyperinflammatory monocyte responses associate with MAC lung disease

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Differential immune response induced by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial

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Profile of Mycobacterium tuberculosis-specific CD4 T cells at the site of disease and blood in pericardial tuberculosis

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Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile

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Design and validation of HIV peptide pools for detection of HIV-specific CD4+ and CD8+ T cells

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Upregulation of Activation Induced Cell Markers (AIM) among Severe COVID-19 patients in Bangladesh

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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response

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