Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 70,903 bioRxiv papers from 309,378 authors.

Downloads per author, site-wide

Preprints

Analysis of protein-coding genetic variation in 60,706 humans

• Downloaded 21,578 times
• Download rankings, all-time:
  • Site-wide: 31 out of 70,927
  • In genomics: 7 out of 4,728
• Year to date:
  • Site-wide: 14,282 out of 70,927
• Since beginning of last month:
  • Site-wide: 18,453 out of 70,927

The Repertoire of Mutational Signatures in Human Cancer

• Downloaded 14,706 times
• Download rankings, all-time:
  • Site-wide: 62 out of 70,927
  • In cancer biology: 2 out of 2,408
• Year to date:
  • Site-wide: 196 out of 70,927
• Since beginning of last month:
  • Site-wide: 70 out of 70,927

The evolutionary history of 2,658 cancers

• Downloaded 8,312 times
• Download rankings, all-time:
  • Site-wide: 187 out of 70,927
  • In cancer biology: 6 out of 2,408
• Year to date:
  • Site-wide: 1,376 out of 70,927
• Since beginning of last month:
  • Site-wide: 588 out of 70,927

Rapid and efficient analysis of 20,000 RNA-seq samples with Toil

• Downloaded 5,939 times
• Download rankings, all-time:
  • Site-wide: 344 out of 70,927
  • In bioinformatics: 65 out of 6,940
• Year to date:
  • Site-wide: 7,670 out of 70,927
• Since beginning of last month:
  • Site-wide: 5,108 out of 70,927

The whole-genome panorama of cancer drivers

• Downloaded 5,455 times
• Download rankings, all-time:
  • Site-wide: 399 out of 70,927
  • In cancer biology: 12 out of 2,408
• Year to date:
  • Site-wide: 6,931 out of 70,927
• Since beginning of last month:
  • Site-wide: 4,329 out of 70,927

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

• Downloaded 4,678 times
• Download rankings, all-time:
  • Site-wide: 527 out of 70,927
  • In genomics: 134 out of 4,728
• Year to date:
  • Site-wide: 3,166 out of 70,927
• Since beginning of last month:
  • Site-wide: 2,369 out of 70,927

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

• Downloaded 4,360 times
• Download rankings, all-time:
  • Site-wide: 615 out of 70,927
  • In genomics: 156 out of 4,728
• Year to date:
  • Site-wide: 7,690 out of 70,927
• Since beginning of last month:
  • Site-wide: 8,384 out of 70,927

Local genetic effects on gene expression across 44 human tissues

• Downloaded 4,217 times
• Download rankings, all-time:
  • Site-wide: 654 out of 70,927
  • In genomics: 166 out of 4,728
• Year to date:
  • Site-wide: 20,186 out of 70,927
• Since beginning of last month:
  • Site-wide: 18,009 out of 70,927

The GTEx Consortium atlas of genetic regulatory effects across human tissues

• Downloaded 4,130 times
• Download rankings, all-time:
  • Site-wide: 682 out of 70,927
  • In genetics: 64 out of 3,928
• Year to date:
  • Site-wide: 217 out of 70,927
• Since beginning of last month:
  • Site-wide: 256 out of 70,927

Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types

• Downloaded 4,051 times
• Download rankings, all-time:
  • Site-wide: 714 out of 70,927
  • In cancer biology: 21 out of 2,408
• Year to date:
  • Site-wide: 2,713 out of 70,927
• Since beginning of last month:
  • Site-wide: 6,162 out of 70,927

Scaling computational genomics to millions of individuals with GPUs

• Downloaded 3,053 times
• Download rankings, all-time:
  • Site-wide: 1,219 out of 70,927
  • In genomics: 280 out of 4,728
• Year to date:
  • Site-wide: 8,290 out of 70,927
• Since beginning of last month:
  • Site-wide: 6,130 out of 70,927

Tumor mutational landscape is a record of the pre-malignant state

• Downloaded 2,860 times
• Download rankings, all-time:
  • Site-wide: 1,375 out of 70,927
  • In genomics: 309 out of 4,728
• Year to date:
  • Site-wide: 16,006 out of 70,927
• Since beginning of last month:
  • Site-wide: 7,017 out of 70,927

A comprehensive analysis of RNA sequences reveals macroscopic somatic clonal expansion across normal tissues

• Downloaded 2,820 times
• Download rankings, all-time:
  • Site-wide: 1,401 out of 70,927
  • In genomics: 316 out of 4,728
• Year to date:
  • Site-wide: 7,501 out of 70,927
• Since beginning of last month:
  • Site-wide: 10,188 out of 70,927

A deep learning system can accurately classify primary and metastatic cancers based on patterns of passenger mutations

• Downloaded 2,795 times
• Download rankings, all-time:
  • Site-wide: 1,427 out of 70,927
  • In cancer biology: 40 out of 2,408
• Year to date:
  • Site-wide: 3,656 out of 70,927
• Since beginning of last month:
  • Site-wide: 5,669 out of 70,927

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

• Downloaded 2,076 times
• Download rankings, all-time:
  • Site-wide: 2,424 out of 70,927
  • In cancer biology: 59 out of 2,408
• Year to date:
  • Site-wide: 3,429 out of 70,927
• Since beginning of last month:
  • Site-wide: 3,189 out of 70,927

A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes

• Downloaded 2,023 times
• Download rankings, all-time:
  • Site-wide: 2,536 out of 70,927
  • In cancer biology: 62 out of 2,408
• Year to date:
  • Site-wide: 67,273 out of 70,927
• Since beginning of last month:
  • Site-wide: 62,309 out of 70,927

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

• Downloaded 1,987 times
• Download rankings, all-time:
  • Site-wide: 2,614 out of 70,927
  • In genomics: 533 out of 4,728
• Year to date:
  • Site-wide: 17,870 out of 70,927
• Since beginning of last month:
  • Site-wide: 29,199 out of 70,927

Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences

• Downloaded 1,729 times
• Download rankings, all-time:
  • Site-wide: 3,320 out of 70,927
  • In genomics: 638 out of 4,728
• Year to date:
  • Site-wide: 5,868 out of 70,927
• Since beginning of last month:
  • Site-wide: 5,987 out of 70,927

Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes

• Downloaded 1,701 times
• Download rankings, all-time:
  • Site-wide: 3,402 out of 70,927
  • In genetics: 287 out of 3,928
• Year to date:
  • Site-wide: 54,760 out of 70,927
• Since beginning of last month:
  • Site-wide: 22,130 out of 70,927

Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

• Downloaded 1,665 times
• Download rankings, all-time:
  • Site-wide: 3,535 out of 70,927
  • In bioinformatics: 710 out of 6,940
• Year to date:
  • Site-wide: 16,053 out of 70,927
• Since beginning of last month:
  • Site-wide: 3,254 out of 70,927

Passenger Hotspot Mutations in Cancer

• Downloaded 1,560 times
• Download rankings, all-time:
  • Site-wide: 3,966 out of 70,927
  • In genomics: 719 out of 4,728
• Year to date:
  • Site-wide: 4,714 out of 70,927
• Since beginning of last month:
  • Site-wide: 6,383 out of 70,927

Pathway and network analysis of more than 2,500 whole cancer genomes

• Downloaded 1,299 times
• Download rankings, all-time:
  • Site-wide: 5,380 out of 70,927
  • In cancer biology: 138 out of 2,408
• Year to date:
  • Site-wide: 17,892 out of 70,927
• Since beginning of last month:
  • Site-wide: 15,150 out of 70,927

FireCloud, a scalable cloud-based platform for collaborative genome analysis: Strategies for reducing and controlling costs

• Downloaded 1,037 times
• Download rankings, all-time:
  • Site-wide: 7,824 out of 70,927
  • In bioinformatics: 1,384 out of 6,940
• Year to date:
  • Site-wide: 18,093 out of 70,927
• Since beginning of last month:
  • Site-wide: 16,118 out of 70,927

Cell type specific genetic regulation of gene expression across human tissues

• Downloaded 1,024 times
• Download rankings, all-time:
  • Site-wide: 7,985 out of 70,927
  • In genomics: 1,259 out of 4,728
• Year to date:
  • Site-wide: 1,938 out of 70,927
• Since beginning of last month:
  • Site-wide: 3,281 out of 70,927

Framework For Quality Assessment Of Whole Genome, Cancer Sequences

• Downloaded 910 times
• Download rankings, all-time:
  • Site-wide: 9,687 out of 70,927
  • In genomics: 1,447 out of 4,728
• Year to date:
  • Site-wide: 19,130 out of 70,927
• Since beginning of last month:
  • Site-wide: 63,151 out of 70,927

Expanding discovery from cancer genomes by integrating protein network analyses with in vivo tumorigenesis assays

• Downloaded 846 times
• Download rankings, all-time:
  • Site-wide: 10,892 out of 70,927
  • In cancer biology: 323 out of 2,408
• Year to date:
  • Site-wide: 47,298 out of 70,927
• Since beginning of last month:
  • Site-wide: 35,807 out of 70,927

Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes

• Downloaded 610 times
• Download rankings, all-time:
  • Site-wide: 17,535 out of 70,927
  • In bioinformatics: 2,666 out of 6,940
• Year to date:
  • Site-wide: 24,021 out of 70,927
• Since beginning of last month:
  • Site-wide: 67,067 out of 70,927

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

• Downloaded 587 times
• Download rankings, all-time:
  • Site-wide: 18,517 out of 70,927
  • In genetics: 1,229 out of 3,928
• Year to date:
  • Site-wide: 38,991 out of 70,927
• Since beginning of last month:
  • Site-wide: 42,641 out of 70,927

The Tangent copy-number inference pipeline for cancer genome analyses

• Downloaded 534 times
• Download rankings, all-time:
  • Site-wide: 21,007 out of 70,927
  • In bioinformatics: 3,051 out of 6,940
• Year to date:
  • Site-wide: 7,929 out of 70,927
• Since beginning of last month:
  • Site-wide: 19,777 out of 70,927

Calling Somatic SNVs and Indels with Mutect2

• Downloaded 349 times
• Download rankings, all-time:
  • Site-wide: 34,097 out of 70,927
  • In bioinformatics: 4,279 out of 6,940
• Year to date:
  • Site-wide: 1,990 out of 70,927
• Since beginning of last month:
  • Site-wide: 393 out of 70,927