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Author: Markku Laakso

  • Most recently observed institution: Department of Medicine, Kuopio University Hospital

Rankings

  • All-time downloads: 55,675 (rank: 2,154 out of 514,049)
  • Categories:
    • bioinformatics: 1,562 (rank: 8,151 (tie) out of 37,098)
    • epidemiology: 316 (rank: 15,853 (tie) out of 23,860)
    • genetic and genomic medicine: 2,278 (rank: 223 out of 6,816)
    • genetics: 24,953 (rank: 259 out of 38,823)
    • genomics: 26,466 (rank: 316 out of 45,851)
    • microbiology: 100 (rank: 48,981 (tie) out of 52,674)

Downloads per author, site-wide

Preprints

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
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Integrative approaches for large-scale transcriptome-wide association studies

genetics more details view paper
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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

genetics more details view paper
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Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes

genetics more details view paper
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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

genetics more details view paper
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Reverse GWAS: Using Genetics to Identify and Model Phenotypic Subtypes

genetics more details view paper
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    • In genetics: 447 out of 5,154
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
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Association Analysis and Meta-Analysis of Multi-allelic Variants for Large Scale Sequence Data

bioinformatics more details view paper
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Genetics of human gut microbiome composition

genetics more details view paper
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    • In genetics: 512 out of 5,154
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Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

genomics more details view paper
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    • In genomics: 1,232 out of 6,457
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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

genetics more details view paper
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    • In genetics: 748 out of 5,154
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    • Site-wide: 58,241 out of 119,227

Efficient estimation and applications of cross-validated genetic predictions

genetics more details view paper
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    • In genetics: 955 out of 5,154
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Epigenome-wide association in adipose tissue from the METSIM cohort

genetics more details view paper
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Heterozygous RFX6 protein truncating variants cause Maturity-Onset Diabetes of the Young (MODY) with reduced penetrance

genetics more details view paper
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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
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Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 706 times
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    • In genetic and genomic medicine: 60 out of 497
  • Year to date:
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Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 64 out of 497
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Interactions between genetic variation and cellular environment in skeletal muscle gene expression

genetics more details view paper
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    • In genetics: 1,913 out of 5,154
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Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

genetics more details view paper
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    • In genetics: 1,918 out of 5,154
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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
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    • In genetics: 1,954 out of 5,154
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A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

genetics more details view paper
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ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

genetic and genomic medicine more details view paper
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Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 153 out of 497
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Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium

epidemiology more details view paper
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Proper Conditional Analysis in the Presence of Missing Data Identified Novel Independently Associated Low Frequency Variants in Nicotine Dependence Genes

genetics more details view paper
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    • In genetics: 3,875 out of 5,154
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Machine learning reveals time-varying microbial predictors with complex effects on glucose regulation

microbiology more details view paper
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    • In microbiology: 8,369 out of 9,418
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Mitochondrial genome copy number in human blood-derived DNA is strongly associated with insulin levels and related metabolic traits and primarily reflects cell-type composition differences

genetic and genomic medicine more details view paper
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