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Author: Dominic Holland

  • Most recently observed institution: Center for Multimodal Imaging and Genetics, University of California at San Diego

Rankings

  • All-time downloads: 16,874 (rank: 3,886 out of 393,295)
  • Categories:
    • bioinformatics: 194 (rank: 29,834 (tie) out of 33,499)
    • genetics: 11,109 (rank: 1,157 out of 36,121)
    • genomics: 4,982 (rank: 3,806 (tie) out of 41,868)
    • neuroscience: 589 (rank: 27,912 (tie) out of 65,842)

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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    • In genetics: 34 out of 4,731
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    • Site-wide: 5,163 out of 92,062
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    • Site-wide: 8,013 out of 92,062

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

genomics more details view paper
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    • In genomics: 418 out of 5,810
  • Year to date:
    • Site-wide: 4,026 out of 92,062
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    • Site-wide: 6,677 out of 92,062

Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

genomics more details view paper
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    • Site-wide: 6,192 out of 92,062
    • In genomics: 984 out of 5,810
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    • Site-wide: 9,938 out of 92,062
  • Since beginning of last month:
    • Site-wide: 10,185 out of 92,062

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

genetics more details view paper
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    • Site-wide: 9,158 out of 92,062
    • In genetics: 643 out of 4,731
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    • Site-wide: 29,359 out of 92,062

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

genetics more details view paper
  • Downloaded 973 times
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    • Site-wide: 12,388 out of 92,062
    • In genetics: 821 out of 4,731
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    • Site-wide: 62,515 out of 92,062
  • Since beginning of last month:
    • Site-wide: 27,507 out of 92,062

Personalized genetic assessment of age associated Alzheimers disease risk

genetics more details view paper
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    • Site-wide: 13,597 out of 92,062
    • In genetics: 896 out of 4,731
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    • Site-wide: 71,555 out of 92,062
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    • Site-wide: 62,662 out of 92,062

Evidence of natural selection in human complex phenotypes from GWAS summary statistics

genomics more details view paper
  • Downloaded 715 times
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    • In genomics: 2,354 out of 5,810
  • Year to date:
    • Site-wide: 7,494 out of 92,062
  • Since beginning of last month:
    • Site-wide: 7,257 out of 92,062

Making the MOSTest of imaging genetics

neuroscience more details view paper
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    • Site-wide: 26,339 out of 92,062
    • In neuroscience: 4,443 out of 16,376
  • Year to date:
    • Site-wide: 14,149 out of 92,062
  • Since beginning of last month:
    • Site-wide: 30,537 out of 92,062

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

genetics more details view paper
  • Downloaded 396 times
  • Download rankings, all-time:
    • Site-wide: 42,309 out of 92,062
    • In genetics: 2,453 out of 4,731
  • Year to date:
    • Site-wide: 76,016 out of 92,062
  • Since beginning of last month:
    • Site-wide: 70,342 out of 92,062

Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition

genetics more details view paper
  • Downloaded 387 times
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    • Site-wide: 43,319 out of 92,062
    • In genetics: 2,505 out of 4,731
  • Year to date:
    • Site-wide: 54,248 out of 92,062
  • Since beginning of last month:
    • Site-wide: 25,144 out of 92,062

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

genetics more details view paper
  • Downloaded 317 times
  • Download rankings, all-time:
    • Site-wide: 52,444 out of 92,062
    • In genetics: 2,950 out of 4,731
  • Year to date:
    • Site-wide: 55,733 out of 92,062
  • Since beginning of last month:
    • Site-wide: 85,803 out of 92,062

MODE for detecting and estimating genetic causal variants

bioinformatics more details view paper
  • Downloaded 194 times
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    • Site-wide: 72,387 out of 92,062
    • In bioinformatics: 7,346 out of 8,636
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 88,441 out of 92,062

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