Author: Peter D Kwong

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Preprints

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses

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Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

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Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization

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The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

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Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

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Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

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Routine Single Particle CryoEM Sample and Grid Characterization by Tomography

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Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

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Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

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Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

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Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants

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Real-time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone

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Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

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Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies

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HIV-1 Envelope and MPER antibody structures in lipid assemblies

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High-Throughput, Single-Copy Sequencing Reveals SARS-CoV-2 Spike Variants Coincident with Mounting Humoral Immunity during Acute COVID-19

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Accurate Prediction of Antibody Resistance in Clinical HIV-1 Isolates

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Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques

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cAb-Rep: A Database of Curated Antibody Repertoires for Exploring antibody diversity and Predicting Antibody Prevalence

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Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

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Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

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Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

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Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

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Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

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Protective Antibodies Against Human Parainfluenza Virus Type 3 (HPIV3) Infection

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Virus-Like Particle Based-Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

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Impact of glycan positioning on HIV-1 Env glycan shield density, function, and antibody recognition

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Augmenting Neutralization breadth against Diverse HIV-1 by increasing the Ab-Ag interface on V2

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