Author: Tongqing Zhou

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Preprints

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

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Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

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Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

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Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

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Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

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  • In biochemistry: 251
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Real-time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone

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Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants

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Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

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Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

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A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

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High-Throughput, Single-Copy Sequencing Reveals SARS-CoV-2 Spike Variants Coincident with Mounting Humoral Immunity during Acute COVID-19

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Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

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Augmenting Neutralization breadth against Diverse HIV-1 by increasing the Ab-Ag interface on V2

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  • Site-wide: 155,359
  • In immunology: 4,687
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