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Author: Barton F. Haynes

Rankings

  • All-time downloads: 53,538 (rank: 4,453 (tie) )
  • Categories:
    • biochemistry: 4,843 (rank: 846 (tie) )
    • biophysics: 3,934 (rank: 1,058 (tie) )
    • immunology: 24,614 (rank: 643 )
    • infectious diseases: 8,133 (rank: 8,071 (tie) )
    • microbiology: 5,442 (rank: 3,683 )

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Preprints

Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism

immunology more details view paper

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D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization.

infectious diseases more details view paper
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    • Site-wide: 1,629
    • In infectious diseases: 475
  • Year to date:
    • Site-wide: 31,467
  • Since beginning of last month:
    • Site-wide: 30,778

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

immunology more details view paper
  • Downloaded 6,170 times
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    • Site-wide: 2,388
    • In immunology: 97
  • Year to date:
    • Site-wide: 3,590
  • Since beginning of last month:
    • Site-wide: 1,411

Structural diversity of the SARS-CoV-2 Omicron spike

biochemistry more details view paper
  • Downloaded 3,310 times
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    • Site-wide: 5,655
    • In biochemistry: 131
  • Year to date:
    • Site-wide: 325
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Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity

microbiology more details view paper
  • Downloaded 3,204 times
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    • Site-wide: 5,927
    • In microbiology: 383
  • Year to date:
    • Site-wide: 11,848
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Controlling the SARS-CoV-2 Spike Glycoprotein Conformation

immunology more details view paper
  • Downloaded 2,710 times
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    • Site-wide: 7,545
    • In immunology: 271
  • Year to date:
    • Site-wide: 63,053
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    • Site-wide: 54,433

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

immunology more details view paper
  • Downloaded 2,318 times
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    • Site-wide: 9,506
    • In immunology: 357
  • Year to date:
    • Site-wide: 12,083
  • Since beginning of last month:
    • Site-wide: 15,470

Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation

biophysics more details view paper
  • Downloaded 2,146 times
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    • Site-wide: 10,650
    • In biophysics: 204
  • Year to date:
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SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys

immunology more details view paper
  • Downloaded 2,131 times
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    • Site-wide: 10,777
    • In immunology: 393
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Single cell analysis of quiescent HIV infection reveals host transcriptional profiles that regulate proviral latency

microbiology more details view paper
  • Downloaded 2,002 times
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    • Site-wide: 11,851
    • In microbiology: 661
  • Year to date:
    • Site-wide: 101,233
  • Since beginning of last month:
    • Site-wide: 113,963

Cold sensitivity of the SARS-CoV-2 spike ectodomain

biochemistry more details view paper
  • Downloaded 1,958 times
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    • Site-wide: 12,261
    • In biochemistry: 231
  • Year to date:
    • Site-wide: 69,408
  • Since beginning of last month:
    • Site-wide: 76,086

D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction

biophysics more details view paper
  • Downloaded 1,909 times
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    • Site-wide: 12,714
    • In biophysics: 259
  • Year to date:
    • Site-wide: 72,098
  • Since beginning of last month:
    • Site-wide: 97,892

A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies

immunology more details view paper
  • Downloaded 1,896 times
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    • Site-wide: 12,837
    • In immunology: 471
  • Year to date:
    • Site-wide: 21,485
  • Since beginning of last month:
    • Site-wide: 17,045

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

immunology more details view paper
  • Downloaded 1,679 times
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    • Site-wide: 15,359
    • In immunology: 523
  • Year to date:
    • Site-wide: 76,548
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    • Site-wide: 71,571

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

immunology more details view paper
  • Downloaded 1,619 times
  • Download rankings, all-time:
    • Site-wide: 16,207
    • In immunology: 584
  • Year to date:
    • Site-wide: 29,594
  • Since beginning of last month:
    • Site-wide: 47,694

Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike

biochemistry more details view paper
  • Downloaded 1,549 times
  • Download rankings, all-time:
    • Site-wide: 17,411
    • In biochemistry: None
  • Year to date:
    • Site-wide: 905
  • Since beginning of last month:
    • Site-wide: 1,210

Disease diagnostics using machine learning of immune receptors

immunology more details view paper
  • Downloaded 1,216 times
  • Download rankings, all-time:
    • Site-wide: 25,355
    • In immunology: None
  • Year to date:
    • Site-wide: 1,262
  • Since beginning of last month:
    • Site-wide: 467

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

immunology more details view paper
  • Downloaded 1,204 times
  • Download rankings, all-time:
    • Site-wide: 25,719
    • In immunology: 1,497
  • Year to date:
    • Site-wide: 1,276
  • Since beginning of last month:
    • Site-wide: 6,368

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

immunology more details view paper
  • Downloaded 1,078 times
  • Download rankings, all-time:
    • Site-wide: 30,453
    • In immunology: 1,074
  • Year to date:
    • Site-wide: 34,995
  • Since beginning of last month:
    • Site-wide: 45,456

Mouse and Human Antibodies that Bind HLA-E-Leader Peptide Complexes and Enhance NK Cell Cytotoxicity

immunology more details view paper
  • Downloaded 764 times
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    • Site-wide: 50,672
    • In immunology: 1,753
  • Year to date:
    • Site-wide: 24,382
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    • Site-wide: 32,519

Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles

immunology more details view paper
  • Downloaded 657 times
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    • Site-wide: 62,522
    • In immunology: 2,177
  • Year to date:
    • Site-wide: 26,259
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    • Site-wide: 27,855

Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

immunology more details view paper
  • Downloaded 644 times
  • Download rankings, all-time:
    • Site-wide: 64,161
    • In immunology: 2,026
  • Year to date:
    • Site-wide: 66,440
  • Since beginning of last month:
    • Site-wide: 65,248

Functional Improbable Antibody Mutations Critical for HIV Broadly Neutralizing Antibody Development

immunology more details view paper
  • Downloaded 639 times
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    • Site-wide: 64,827
    • In immunology: 1,894
  • Year to date:
    • Site-wide: 173,811
  • Since beginning of last month:
    • Site-wide: 142,500

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

immunology more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 66,220
    • In immunology: 2,934
  • Year to date:
    • Site-wide: 17,569
  • Since beginning of last month:
    • Site-wide: 3,139

Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques

immunology more details view paper
  • Downloaded 627 times
  • Download rankings, all-time:
    • Site-wide: 66,371
    • In immunology: 1,981
  • Year to date:
    • Site-wide: 119,162
  • Since beginning of last month:
    • Site-wide: 84,200

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

immunology more details view paper
  • Downloaded 575 times
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    • Site-wide: 74,145
    • In immunology: 2,146
  • Year to date:
    • Site-wide: 169,120
  • Since beginning of last month:
    • Site-wide: 118,493

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure

microbiology more details view paper
  • Downloaded 508 times
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    • Site-wide: 86,011
    • In microbiology: 5,617
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    • Site-wide: 86,469
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    • Site-wide: 47,713

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

biochemistry more details view paper
  • Downloaded 399 times
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    • Site-wide: 110,566
    • In biochemistry: 3,024
  • Year to date:
    • Site-wide: 162,783
  • Since beginning of last month:
    • Site-wide: 125,977

Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models

immunology more details view paper
  • Downloaded 347 times
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    • Site-wide: 124,670
    • In immunology: 3,635
  • Year to date:
    • Site-wide: 150,530
  • Since beginning of last month:
    • Site-wide: 112,504

Boosting with ALVAC-HIV and AIDSVAX B/E enhances Env constant region 1 and 2 antibody-dependent cellular cytotoxicity

immunology more details view paper
  • Downloaded 344 times
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    • Site-wide: 125,378
    • In immunology: 3,686
  • Year to date:
    • Site-wide: 130,077
  • Since beginning of last month:
    • Site-wide: 93,250

HIV-1 Vpu restricts Fc-mediated effector functions in vivo

microbiology more details view paper
  • Downloaded 325 times
  • Download rankings, all-time:
    • Site-wide: 130,916
    • In microbiology: None
  • Year to date:
    • Site-wide: 9,606
  • Since beginning of last month:
    • Site-wide: 22,399

Identification of CDRH3 Loops in the Naive B Cell Receptor Repertoire that Can Be Engaged by Candidate Immunogens

immunology more details view paper
  • Downloaded 294 times
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    • Site-wide: 140,291
    • In immunology: 4,374
  • Year to date:
    • Site-wide: 22,985
  • Since beginning of last month:
    • Site-wide: 56,554

Subordinate effect of -21M HLA-B dimorphism on NK cell repertoire diversity and function in HIV-1 infected individuals of African origin

immunology more details view paper
  • Downloaded 236 times
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    • Site-wide: 157,160
    • In immunology: 4,484
  • Year to date:
    • Site-wide: 184,197
  • Since beginning of last month:
    • Site-wide: 152,631

Maternal alum-adjuvanted recombinant HIV Env vaccine does not enhance autologous virus neutralization in HIV-infected pregnant women

immunology more details view paper
  • Downloaded 227 times
  • Download rankings, all-time:
    • Site-wide: 159,694
    • In immunology: 4,557
  • Year to date:
    • Site-wide: 187,550
  • Since beginning of last month:
    • Site-wide: 169,776

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