Author: Steven G Rozen

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Preprints

The Repertoire of Mutational Signatures in Human Cancer

• Downloaded 20,552 times
• Download rankings, all-time:
  • Site-wide: 519
  • In cancer biology: 2
• Year to date:
  • Site-wide: 16,979
• Since beginning of last month:
  • Site-wide: 23,492

Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

• Downloaded 2,695 times
• Download rankings, all-time:
  • Site-wide: 7,608
  • In bioinformatics: 1,144
• Year to date:
  • Site-wide: 1,838
• Since beginning of last month:
  • Site-wide: 2,119

Identification of novel mutational signatures in Asian oral squamous cell carcinomas associated with bacterial infections

• Downloaded 1,212 times
• Download rankings, all-time:
  • Site-wide: 25,480
  • In genomics: 2,177
• Year to date:
  • Site-wide: 69,555
• Since beginning of last month:
  • Site-wide: 77,603

Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide

• Downloaded 874 times
• Download rankings, all-time:
  • Site-wide: 41,480
  • In genomics: 3,116
• Year to date:
  • Site-wide: 138,980
• Since beginning of last month:
  • Site-wide: 141,489

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

• Downloaded 786 times
• Download rankings, all-time:
  • Site-wide: 48,620
  • In bioinformatics: 4,669
• Year to date:
  • Site-wide: 148,641
• Since beginning of last month:
  • Site-wide: 116,410

Recurrent mutations in topoisomerase 2a cause a novel mutator phenotype in human cancers

• Downloaded 744 times
• Download rankings, all-time:
  • Site-wide: 52,525
  • In genomics: 3,906
• Year to date:
  • Site-wide: 48,091
• Since beginning of last month:
  • Site-wide: 68,097

mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery

• Downloaded 491 times
• Download rankings, all-time:
  • Site-wide: 89,387
  • In bioinformatics: 11,422
• Year to date:
  • Site-wide: 5,126
• Since beginning of last month:
  • Site-wide: 11,589

Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era

• Downloaded 319 times
• Download rankings, all-time:
  • Site-wide: 132,762
  • In genomics: 6,856
• Year to date:
  • Site-wide: 180,920
• Since beginning of last month:
  • Site-wide: 179,860

Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

• Downloaded 210 times
• Download rankings, all-time:
  • Site-wide: 164,309
  • In cancer biology: 4,988
• Year to date:
  • Site-wide: 71,553
• Since beginning of last month:
  • Site-wide: 69,593