Author: Christopher Simon Haley

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Preprints

Genetic mechanisms of critical illness in Covid-19

• Downloaded 11,186 times
• Download rankings, all-time:
  • Site-wide: 1,204
  • In intensive care and critical care medicine: 8
• Year to date:
  • Site-wide: 65,924
• Since beginning of last month:
  • Site-wide: 84,611

Genomic analysis of family data reveals additional genetic effects on intelligence and personality

• Downloaded 4,923 times
• Download rankings, all-time:
  • Site-wide: 3,568
  • In genetics: 103
• Year to date:
  • Site-wide: 1,516
• Since beginning of last month:
  • Site-wide: 9,565

Beyond power: Multivariate discovery, replication, and interpretation of pleiotropic loci using summary association statistics

• Downloaded 4,342 times
• Download rankings, all-time:
  • Site-wide: 4,257
  • In genetics: 125
• Year to date:
  • Site-wide: 62,694
• Since beginning of last month:
  • Site-wide: 61,221

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

• Downloaded 2,813 times
• Download rankings, all-time:
  • Site-wide: 7,999
  • In genetics: 298
• Year to date:
  • Site-wide: 36,125
• Since beginning of last month:
  • Site-wide: 60,627

Bayesian reassessment of the epigenetic architecture of complex traits

• Downloaded 1,427 times
• Download rankings, all-time:
  • Site-wide: 22,842
  • In genomics: 2,001
• Year to date:
  • Site-wide: 113,500
• Since beginning of last month:
  • Site-wide: 59,548

Epigenetic prediction of complex traits and death

• Downloaded 1,136 times
• Download rankings, all-time:
  • Site-wide: 32,791
  • In genomics: 2,691
• Year to date:
  • Site-wide: 96,422
• Since beginning of last month:
  • Site-wide: 199,144

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

• Downloaded 1,030 times
• Download rankings, all-time:
  • Site-wide: 38,092
  • In bioinformatics: 3,978
• Year to date:
  • Site-wide: 148,726
• Since beginning of last month:
  • Site-wide: 135,675

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

• Downloaded 998 times
• Download rankings, all-time:
  • Site-wide: 39,980
  • In genetics: 1,582
• Year to date:
  • Site-wide: 93,525
• Since beginning of last month:
  • Site-wide: 208,849

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

• Downloaded 804 times
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  • Site-wide: 55,687
  • In genetics: 2,148
• Year to date:
  • Site-wide: 132,645
• Since beginning of last month:
  • Site-wide: 208,814

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

• Downloaded 582 times
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  • Site-wide: 86,886
  • In genomics: 5,519
• Year to date:
  • Site-wide: 166,367
• Since beginning of last month:
  • Site-wide: 184,653

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2

• Downloaded 521 times
• Download rankings, all-time:
  • Site-wide: 99,438
  • In genetics: 3,792
• Year to date:
  • Site-wide: 60,803
• Since beginning of last month:
  • Site-wide: 128,560

Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

• Downloaded 475 times
• Download rankings, all-time:
  • Site-wide: 110,204
  • In genetics: 4,166
• Year to date:
  • Site-wide: 132,538
• Since beginning of last month:
  • Site-wide: 141,484

Genome-wide methylation data improves dissection of the effect of smoking on body mass index.

• Downloaded 428 times
• Download rankings, all-time:
  • Site-wide: 122,161
  • In genomics: 6,849
• Year to date:
  • Site-wide: 183,515
• Since beginning of last month:
  • Site-wide: 183,946

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

• Downloaded 348 times
• Download rankings, all-time:
  • Site-wide: 145,520
  • In genetics: 5,399
• Year to date:
  • Site-wide: 188,290
• Since beginning of last month:
  • Site-wide: 198,253

SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): joint mapping of common and rare variation affecting complex traits

• Downloaded 275 times
• Download rankings, all-time:
  • Site-wide: 167,618
  • In genomics: 8,375
• Year to date:
  • Site-wide: 101,243
• Since beginning of last month:
  • Site-wide: 193,813

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome

• Downloaded 199 times
• Download rankings, all-time:
  • Site-wide: 187,837
  • In genetics: 6,683
• Year to date:
  • Site-wide: 178,363
• Since beginning of last month:
  • Site-wide: 193,672

Genome-by-Trauma Interaction Effects in Depression

• Downloaded 198 times
• Download rankings, all-time:
  • Site-wide: 187,936
  • In genetic and genomic medicine: 1,412
• Year to date:
  • Site-wide: 181,294
• Since beginning of last month:
  • Site-wide: 169,045

Impact of mixing between parallel year groups on genomic prediction in Atlantic salmon breeding programmes under random selection

• Downloaded 43 times
• Download rankings, all-time:
  • Site-wide: 216,454
  • In genetics: None
• Year to date:
  • Site-wide: 129,463
• Since beginning of last month:
  • Site-wide: 9,787