Author: Jonathan Flint

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Preprints

A comprehensive map of genetic variation in the world's largest ethnic group - Han Chinese

• Downloaded 6,495 times
• Download rankings, all-time:
  • Site-wide: 2,227
  • In genetics: 58
• Year to date:
  • Site-wide: 40,147
• Since beginning of last month:
  • Site-wide: 41,970

Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing

• Downloaded 6,360 times
• Download rankings, all-time:
  • Site-wide: 2,288
  • In infectious diseases: 634
• Year to date:
  • Site-wide: 5,577
• Since beginning of last month:
  • Site-wide: 3,516

Challenges and recommendations to improve installability and archival stability of omics computational tools

• Downloaded 5,628 times
• Download rankings, all-time:
  • Site-wide: 2,692
  • In bioinformatics: 178
• Year to date:
  • Site-wide: 72,507
• Since beginning of last month:
  • Site-wide: 77,895

A comprehensive benchmarking of WGS-based structural variant callers

• Downloaded 3,260 times
• Download rankings, all-time:
  • Site-wide: 5,784
  • In bioinformatics: 540
• Year to date:
  • Site-wide: 9,256
• Since beginning of last month:
  • Site-wide: 12,872

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

• Downloaded 2,312 times
• Download rankings, all-time:
  • Site-wide: 9,542
  • In genetics: 366
• Year to date:
  • Site-wide: 51,802
• Since beginning of last month:
  • Site-wide: 46,487

Estimating Heritability and Genetic Correlation in Case Control Studies Directly and with Summary Statistics

• Downloaded 1,842 times
• Download rankings, all-time:
  • Site-wide: 13,383
  • In genetics: 509
• Year to date:
  • Site-wide: 104,370
• Since beginning of last month:
  • Site-wide: 130,911

Reverse GWAS: Using Genetics to Identify and Model Phenotypic Subtypes

• Downloaded 1,709 times
• Download rankings, all-time:
  • Site-wide: 14,965
  • In genetics: 586
• Year to date:
  • Site-wide: 149,415
• Since beginning of last month:
  • Site-wide: 131,149

GxEMM: Extending linear mixed models to general gene-environment interactions

• Downloaded 1,693 times
• Download rankings, all-time:
  • Site-wide: 15,176
  • In genetics: 600
• Year to date:
  • Site-wide: 125,603
• Since beginning of last month:
  • Site-wide: 92,750

Multiple laboratory mouse reference genomes define strain specific haplotypes and novel functional loci

• Downloaded 1,692 times
• Download rankings, all-time:
  • Site-wide: 15,194
  • In genomics: 1,373
• Year to date:
  • Site-wide: 77,061
• Since beginning of last month:
  • Site-wide: 72,080

Rapid cost-effective viral genome sequencing by V-seq

• Downloaded 1,184 times
• Download rankings, all-time:
  • Site-wide: 26,341
  • In genomics: 2,263
• Year to date:
  • Site-wide: 66,469
• Since beginning of last month:
  • Site-wide: 52,116

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation, and homozygous truncating mutations

• Downloaded 1,028 times
• Download rankings, all-time:
  • Site-wide: 32,640
  • In genomics: 2,580
• Year to date:
  • Site-wide: 186,645
• Since beginning of last month:
  • Site-wide: 178,613

Leveraging eQTLs to identify individual-level tissue of interest for a complex trait

• Downloaded 982 times
• Download rankings, all-time:
  • Site-wide: 34,974
  • In genetics: 1,392
• Year to date:
  • Site-wide: 139,150
• Since beginning of last month:
  • Site-wide: 119,347

Cross-trait assortative mating is widespread and inflates genetic correlation estimates

• Downloaded 956 times
• Download rankings, all-time:
  • Site-wide: 36,371
  • In genetics: None
• Year to date:
  • Site-wide: 1,812
• Since beginning of last month:
  • Site-wide: 3,617

TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

• Downloaded 606 times
• Download rankings, all-time:
  • Site-wide: 69,422
  • In bioinformatics: 6,243
• Year to date:
  • Site-wide: 133,896
• Since beginning of last month:
  • Site-wide: 117,357

Genomic epidemiology of the Los Angeles COVID-19 outbreak

• Downloaded 530 times
• Download rankings, all-time:
  • Site-wide: 81,924
  • In epidemiology: 3,523
• Year to date:
  • Site-wide: 82,030
• Since beginning of last month:
  • Site-wide: 106,167

Increasing the resolution and precision of psychiatric GWAS by re-imputing summary statistics using a large, diverse reference panel

• Downloaded 461 times
• Download rankings, all-time:
  • Site-wide: 95,883
  • In bioinformatics: 7,926
• Year to date:
  • Site-wide: 158,878
• Since beginning of last month:
  • Site-wide: 146,053

Pathway-based polygenic risk implicates GO: 17144 drug metabolism in recurrent depressive disorder

• Downloaded 443 times
• Download rankings, all-time:
  • Site-wide: 100,045
  • In genetics: 3,749
• Year to date:
  • Site-wide: 176,812
• Since beginning of last month:
  • Site-wide: 160,528

Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

• Downloaded 269 times
• Download rankings, all-time:
  • Site-wide: 147,711
  • In bioinformatics: 11,701
• Year to date:
  • Site-wide: 67,315
• Since beginning of last month:
  • Site-wide: 18,847

Coping-Style Behaviour Identified by a Survey of Parent-of-Origin Effects in the Rat

• Downloaded 217 times
• Download rankings, all-time:
  • Site-wide: 162,430
  • In genetics: 5,800
• Year to date:
  • Site-wide: 183,538
• Since beginning of last month:
  • Site-wide: 171,568