Author: Eilis Hannon

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Preprints

Sex differences in gene expression in the human fetal brain

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Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits.

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  • Site-wide: 15,704
  • In genetics: 802
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  • Site-wide: 80,500
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  • Site-wide: 80,500

Properties of the epigenetic clock and age acceleration

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  • Site-wide: 27,172
  • In genomics: 2,556
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  • Site-wide: 114,051
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Meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

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  • Site-wide: 30,137
  • In genomics: 2,744
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Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

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  • Site-wide: 36,668
  • In genetics: 1,798
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  • Site-wide: 84,290
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Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

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  • In genomics: 3,215
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Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex

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  • Site-wide: 38,520
  • In genomics: 3,274
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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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  • Site-wide: 39,398
  • In genetic and genomic medicine: 112
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Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models.

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5-Hydroxymethylcytosine Is Highly Dynamic Across Human Fetal Brain Development

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Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic forms of autism in postmortem human brain tissue.

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  • In genomics: 3,792
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Schizophrenia is characterized by age- and sex-specific effects on epigenetic aging

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  • Site-wide: 57,150
  • In genomics: 4,316
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Assessing the co-variability of DNA methylation across peripheral cells and tissues: implications for the interpretation of findings in epigenetic epidemiology

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  • In genomics: 5,322
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Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits

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  • In genetics: 4,111
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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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  • In genetics: 4,181
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Major surgery induces acute changes in DNA methylation associated with activation of the immune response.

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Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways

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  • Site-wide: 106,268
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Novel epigenetic clock for fetal brain development predicts fetal epigenetic age for iPSCs and iPSC-derived neurons.

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  • Site-wide: 112,571
  • In neuroscience: 17,502
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Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation

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  • Site-wide: 113,758
  • In bioinformatics: 9,363
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  • Site-wide: 6,866
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DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

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  • Site-wide: 115,714
  • In bioinformatics: 9,492
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A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens

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  • Site-wide: 119,868
  • In neuroscience: 18,581
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