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Author: Paul C Boutros

Rankings

  • All-time downloads: 55,739 (rank: 2,152 out of 514,049)
  • Categories:
    • bioinformatics: 12,486 (rank: 444 out of 37,098)
    • cancer biology: 26,109 (rank: 22 out of 31,671)
    • genomics: 17,144 (rank: 596 out of 45,851)

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Preprints

The evolutionary history of 2,658 cancers

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Best Practices for Benchmarking Germline Small Variant Calls in Human Genomes

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A robust benchmark for germline structural variant detection

genomics more details view paper
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    • In genomics: 157 out of 6,457
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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

cancer biology more details view paper
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    • In cancer biology: 22 out of 3,772
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Nanocall: An Open Source Basecaller for Oxford Nanopore Sequencing Data

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    • In bioinformatics: 497 out of 9,634
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A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

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Candidate cancer driver mutations in super-enhancers and long-range chromatin interaction networks

cancer biology more details view paper
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A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

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Sex Differences in Oncogenic Mutational Processes

cancer biology more details view paper
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    • In cancer biology: 89 out of 3,772
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    • Site-wide: 61,858 out of 119,227

Creating Standards for Evaluating Tumour Subclonal Reconstruction

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    • In bioinformatics: 833 out of 9,634
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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

cancer biology more details view paper
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    • Site-wide: 7,651 out of 119,227
    • In cancer biology: 141 out of 3,772
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    • Site-wide: 27,788 out of 119,227
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    • Site-wide: 33,205 out of 119,227

Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers

cancer biology more details view paper
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    • In cancer biology: 217 out of 3,772
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    • Site-wide: 37,959 out of 119,227

Kronos: a workflow assembler for genome analytics and informatics

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    • In bioinformatics: 1,439 out of 9,634
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    • Site-wide: 83,397 out of 119,227
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    • Site-wide: 83,567 out of 119,227

The Origins and Consequences of Localized and Global Somatic Hypermutation

cancer biology more details view paper
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    • In cancer biology: 263 out of 3,772
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    • Site-wide: 18,094 out of 119,227
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    • Site-wide: 28,493 out of 119,227

Integrative pathway enrichment analysis of multivariate omics data

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    • In bioinformatics: 1,585 out of 9,634
  • Year to date:
    • Site-wide: 33,793 out of 119,227
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    • Site-wide: 77,866 out of 119,227

Quantifying the Influence of Mutation Detection on Tumour Subclonal Reconstruction

cancer biology more details view paper
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    • In cancer biology: 329 out of 3,772
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Fast Nonnegative Matrix Factorization and Applications to Pattern Extraction, Deconvolution and Imputation

bioinformatics more details view paper
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    • In bioinformatics: 2,437 out of 9,634
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    • Site-wide: 46,101 out of 119,227

Combining accurate tumour genome simulation with crowd-sourcing to benchmark somatic structural variant detection

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    • In bioinformatics: 2,493 out of 9,634
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    • Site-wide: 56,282 out of 119,227

BPG: Seamless, Automated and Interactive Visualization of Scientific Data

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    • Site-wide: 22,719 out of 119,227
    • In bioinformatics: 2,814 out of 9,634
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 50,634 out of 119,227

Prediction of early breast cancer patient survival using ensembles of hypoxia signatures

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    • In bioinformatics: 3,746 out of 9,634
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    • Site-wide: 64,602 out of 119,227
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    • Site-wide: 44,162 out of 119,227

Modeling the MYC-driven normal-to-tumour switch in breast cancer.

cancer biology more details view paper
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    • Site-wide: 38,154 out of 119,227
    • In cancer biology: 1,058 out of 3,772
  • Year to date:
    • Site-wide: 71,038 out of 119,227
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    • Site-wide: 83,196 out of 119,227

Divergent mutational processes distinguish hypoxic and normoxic tumours

cancer biology more details view paper
  • Downloaded 556 times
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    • In cancer biology: 1,078 out of 3,772
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    • Site-wide: 45,265 out of 119,227

Network-Based Biomarkers Enable Cross-Disease Biomarker Discovery

bioinformatics more details view paper
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    • In bioinformatics: 4,631 out of 9,634
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    • Site-wide: 62,129 out of 119,227

Enhancing Knowledge Discovery from Cancer Genomics Data with Galaxy

genomics more details view paper
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    • In genomics: 3,668 out of 6,457
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    • Site-wide: 97,715 out of 119,227

Accurate Reference-Free Somatic Variant-Calling by Integrating Genomic, Sequencing and Population Data

bioinformatics more details view paper
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    • In bioinformatics: 5,164 out of 9,634
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    • Site-wide: 60,316 out of 119,227

DreamAI: algorithm for the imputation of proteomics data

bioinformatics more details view paper
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    • In bioinformatics: 6,291 out of 9,634
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    • Site-wide: 7,574 out of 119,227

Differing total mRNA expression shapes the molecular and clinical phenotype of cancer

genomics more details view paper
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    • In genomics: 4,801 out of 6,457
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    • Site-wide: 7,873 out of 119,227

Subnetwork-based prognostic biomarkers exhibit performance and robustness superior to gene-based biomarkers in breast cancer

bioinformatics more details view paper
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    • In bioinformatics: 6,843 out of 9,634
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    • Site-wide: 86,238 out of 119,227

Germline Contamination and Leakage in Whole Genome Somatic Single Nucleotide Variant Detection

genomics more details view paper
  • Downloaded 265 times
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    • In genomics: 5,192 out of 6,457
  • Year to date:
    • Site-wide: 108,045 out of 119,227
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    • Site-wide: 109,887 out of 119,227

Valection: Design Optimization for Validation and Verification Studies

bioinformatics more details view paper
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    • In bioinformatics: 7,276 out of 9,634
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    • Site-wide: 112,209 out of 119,227

Identifying TCDD-resistance genes via murine and rat comparative genomics and transcriptomics

genomics more details view paper
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    • Site-wide: 81,550 out of 119,227
    • In genomics: 5,307 out of 6,457
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    • Site-wide: 50,765 out of 119,227

HPCI: A Perl module for writing cluster-portable bioinformatics pipelines

bioinformatics more details view paper
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    • In bioinformatics: 7,639 out of 9,634
  • Year to date:
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    • Site-wide: 103,774 out of 119,227

Age Influences on the Molecular Presentation of Tumours

cancer biology more details view paper
  • Downloaded 208 times
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    • Site-wide: 89,936 out of 119,227
    • In cancer biology: 2,743 out of 3,772
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    • Site-wide: 62,620 out of 119,227

Ancestry Influences on the Molecular Presentation of Tumours

cancer biology more details view paper
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    • In cancer biology: 3,405 out of 3,772
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NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

cancer biology more details view paper
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