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Author: Riccardo E. Marioni

Rankings

  • All-time downloads: 63,556 (rank: 3,822 )
  • Categories:
    • bioinformatics: 2,085 (rank: 10,081 )
    • cell biology: 1,430 (rank: 9,150 (tie) )
    • epidemiology: 2,489 (rank: 7,674 )
    • genetic and genomic medicine: 5,698 (rank: 529 )
    • genetics: 28,146 (rank: 313 )
    • genomics: 9,991 (rank: 2,556 )
    • infectious diseases: 6,825 (rank: 9,972 )
    • neurology: 669 (rank: 4,437 (tie) )
    • neuroscience: 1,866 (rank: 19,638 (tie) )
    • pediatrics: 490 (rank: 2,042 (tie) )
    • psychiatry and clinical psychology: 951 (rank: 2,405 (tie) )

Downloads per author, site-wide

Preprints

Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics

infectious diseases more details view paper
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,860 times
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    • Site-wide: 3,542
    • In genetics: 97
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    • Site-wide: 63,394
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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

genetics more details view paper
  • Downloaded 3,527 times
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    • Site-wide: 5,600
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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
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Molecular genetic contributions to self-rated health

genetics more details view paper
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    • Site-wide: 9,843
    • In genetics: 373
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Genetic Prediction of Male Pattern Baldness

genetics more details view paper
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    • Site-wide: 11,653
    • In genetics: 463
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GWAS on family history of Alzheimer's disease

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    • Site-wide: 11,872
    • In genetics: 438
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Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

genetics more details view paper
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    • Site-wide: 14,937
    • In genetics: 585
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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

genetics more details view paper
  • Downloaded 1,777 times
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    • Site-wide: 15,617
    • In genetics: 628
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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
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    • Site-wide: 16,765
    • In genetics: 677
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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
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    • In bioinformatics: 2,062
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Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

cell biology more details view paper
  • Downloaded 1,475 times
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    • Site-wide: 20,908
    • In cell biology: 639
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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
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    • Site-wide: 21,277
    • In genetic and genomic medicine: 121
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Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
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    • Site-wide: 22,481
    • In genomics: 1,929
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Discovery Of 42 Genome-Wide Significant Loci Associated With Dyslexia

epidemiology more details view paper
  • Downloaded 1,185 times
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    • Site-wide: 29,533
    • In epidemiology: 1,914
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Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
  • Downloaded 1,157 times
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    • Site-wide: 30,662
    • In genomics: 2,523
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    • Site-wide: 140,857
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Epigenetic prediction of complex traits and death

genomics more details view paper
  • Downloaded 1,129 times
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    • Site-wide: 31,882
    • In genomics: 2,612
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    • Site-wide: 133,311
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An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
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    • Site-wide: 33,318
    • In genetics: 1,303
  • Year to date:
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Epigenetic scores for the circulating proteome as tools for disease prediction

genomics more details view paper
  • Downloaded 1,063 times
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    • Site-wide: 34,943
    • In genomics: 2,822
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    • Site-wide: 42,726
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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

genomics more details view paper
  • Downloaded 927 times
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    • Site-wide: 43,130
    • In genomics: 3,252
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    • Site-wide: 132,300
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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

genetics more details view paper
  • Downloaded 900 times
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    • Site-wide: 45,054
    • In genetics: 1,721
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    • Site-wide: 164,818

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
  • Downloaded 886 times
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    • Site-wide: 46,225
    • In genetics: 1,804
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    • Site-wide: 104,914

An epigenetic proxy of chronic inflammation outperforms serum levels as a biomarker of brain ageing

neurology more details view paper
  • Downloaded 720 times
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    • Site-wide: 62,888
    • In neurology: 219
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Multivariate Modeling of Direct and Proxy GWAS Indicates Substantial Common Variant Heritability of Alzheimer's Disease

genetic and genomic medicine more details view paper
  • Downloaded 667 times
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    • Site-wide: 69,994
    • In genetic and genomic medicine: 424
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    • Site-wide: 38,677
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A meta-analysis of genome-wide association studies of epigenetic age acceleration

genetics more details view paper
  • Downloaded 661 times
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    • Site-wide: 70,931
    • In genetics: 2,709
  • Year to date:
    • Site-wide: 192,164
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    • Site-wide: 122,532

DNA methylation age acceleration and risk factors for Alzheimer's disease

genomics more details view paper
  • Downloaded 649 times
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    • Site-wide: 72,732
    • In genomics: 4,778
  • Year to date:
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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
  • Downloaded 596 times
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    • Site-wide: 81,043
    • In genomics: 5,208
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    • Site-wide: 147,935
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    • Site-wide: 74,066

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936.

epidemiology more details view paper
  • Downloaded 590 times
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    • Site-wide: 82,129
    • In epidemiology: 3,601
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Age-related clonal haemopoiesis is associated with increased epigenetic age

bioinformatics more details view paper
  • Downloaded 587 times
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    • Site-wide: 82,646
    • In bioinformatics: 7,217
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Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

genomics more details view paper
  • Downloaded 583 times
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    • Site-wide: 83,397
    • In genomics: 5,309
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Blood-based epigenome-wide analyses of cognitive abilities

genetic and genomic medicine more details view paper
  • Downloaded 571 times
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    • In genetic and genomic medicine: 532
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Polygenic predictors of age-related decline in cognitive ability

genomics more details view paper
  • Downloaded 562 times
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    • Site-wide: 87,333
    • In genomics: 5,409
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    • Site-wide: 179,322
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Epigenetic prediction of major depressive disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 547 times
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    • Site-wide: 90,087
    • In psychiatry and clinical psychology: 427
  • Year to date:
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A proteomic survival predictor for COVID-19 patients in intensive care

infectious diseases more details view paper
  • Downloaded 547 times
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    • Site-wide: 90,158
    • In infectious diseases: 5,078
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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
  • Downloaded 511 times
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    • Site-wide: 97,640
    • In genetics: 3,705
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Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2

genetics more details view paper
  • Downloaded 510 times
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    • Site-wide: 97,895
    • In genetics: 3,742
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DNA methylation and brain dysmaturation in preterm infants

pediatrics more details view paper
  • Downloaded 509 times
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    • Site-wide: 98,070
    • In pediatrics: 174
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    • Site-wide: 157,214

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

neuroscience more details view paper
  • Downloaded 505 times
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    • Site-wide: 99,076
    • In neuroscience: 13,911
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    • Site-wide: 201,443

Epigenome-wide analyses identify DNA methylation signatures of dementia risk

genetic and genomic medicine more details view paper
  • Downloaded 503 times
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    • Site-wide: 99,448
    • In genetic and genomic medicine: 608
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Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

genetic and genomic medicine more details view paper
  • Downloaded 502 times
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    • Site-wide: 99,712
    • In genetic and genomic medicine: 709
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Genome and epigenome wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk

genetic and genomic medicine more details view paper
  • Downloaded 501 times
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    • Site-wide: 100,009
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Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

genomics more details view paper
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    • Site-wide: 100,501
    • In genomics: 5,910
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Creating and validating a DNA methylation-based proxy for Interleukin-6

genetic and genomic medicine more details view paper
  • Downloaded 497 times
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    • Site-wide: 100,829
    • In genetic and genomic medicine: 607
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DNAmFitAge: Biological Age Indicator Incorporating Physical Fitness

genetic and genomic medicine more details view paper
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    • Site-wide: 102,762
    • In genetic and genomic medicine: 796
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Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

genomics more details view paper
  • Downloaded 466 times
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    • Site-wide: 108,054
    • In genomics: 6,205
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An epigenetic predictor of death captures multi-modal measures of brain health

neuroscience more details view paper
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    • Site-wide: 112,527
    • In neuroscience: 15,909
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Association of Facial Aging with DNA Methylation and Epigenetic Age Predictions

genetics more details view paper
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    • Site-wide: 115,598
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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

epidemiology more details view paper
  • Downloaded 393 times
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    • Site-wide: 126,946
    • In epidemiology: 5,231
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An epigenome-wide association study of sex-specific chronological ageing

genomics more details view paper
  • Downloaded 391 times
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    • Site-wide: 127,734
    • In genomics: 6,888
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Refining epigenetic prediction of chronological and biological age

genomics more details view paper
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    • Site-wide: 131,793
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A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens

neuroscience more details view paper
  • Downloaded 359 times
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    • In neuroscience: 20,070
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    • Site-wide: 92,324
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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 351 times
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    • Site-wide: 139,348
    • In epidemiology: 5,910
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Epigenetic signatures of starting and stopping smoking

genomics more details view paper
  • Downloaded 350 times
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    • Site-wide: 139,558
    • In genomics: 7,273
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    • Site-wide: 161,045

Age and mortality associated DNA methylation patterns on the X-chromosome in male and female samples

genetics more details view paper
  • Downloaded 344 times
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    • Site-wide: 141,323
    • In genetics: 5,179
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DNA Methylation scores augment 10-year risk prediction of diabetes

genetic and genomic medicine more details view paper
  • Downloaded 343 times
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    • Site-wide: 141,593
    • In genetic and genomic medicine: 1,030
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DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

genetic and genomic medicine more details view paper
  • Downloaded 340 times
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    • Site-wide: 142,373
    • In genetic and genomic medicine: 939
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Neurology-related protein biomarkers are associated with general fluid cognitive ability and brain volume in older age

neuroscience more details view paper
  • Downloaded 337 times
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    • Site-wide: 143,550
    • In neuroscience: 20,560
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    • Site-wide: 175,925
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DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

neuroscience more details view paper
  • Downloaded 314 times
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    • Site-wide: 150,312
    • In neuroscience: 21,715
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    • Site-wide: 184,685
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DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

psychiatry and clinical psychology more details view paper
  • Downloaded 302 times
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    • Site-wide: 153,804
    • In psychiatry and clinical psychology: 934
  • Year to date:
    • Site-wide: 92,223
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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

genomics more details view paper
  • Downloaded 297 times
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    • Site-wide: 155,238
    • In genomics: 7,801
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The influence of biological and statistical properties of CpGs on epigenetic predictions of eighteen traits

genomics more details view paper
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    • In genomics: 8,005
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Epigenetic predictors of lifestyle traits applied to the blood and brain

genetic and genomic medicine more details view paper
  • Downloaded 269 times
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    • Site-wide: 163,498
    • In genetic and genomic medicine: 1,115
  • Year to date:
    • Site-wide: 159,148
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Increase in anticholinergic burden in the UK from 1990 to 2015: a UK Biobank study

epidemiology more details view paper
  • Downloaded 235 times
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    • Site-wide: 173,102
    • In epidemiology: 6,907
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    • Site-wide: 159,364
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Longitudinal Faecal Calprotectin Profiles Characterise Disease Course Heterogeneity in Crohn's Disease

gastroenterology more details view paper
  • Downloaded 216 times
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    • Site-wide: 177,963
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Variation in VKORC1 is associated with vascular dementia

genetics more details view paper
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Association between anticholinergic burden and dementia in UK Biobank

psychiatry and clinical psychology more details view paper
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    • In psychiatry and clinical psychology: 1,229
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Epigenetic markers of adverse lifestyle identified among night shift workers

genetics more details view paper
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    • Site-wide: 200,801
    • In genetics: 6,893
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Anticholinergic burden in middle and older age is associated with lower cognitive function, but not with brain atrophy

epidemiology more details view paper
  • Downloaded 90 times
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    • Site-wide: 202,695
    • In epidemiology: None
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Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders

pediatrics more details view paper
  • Downloaded 56 times
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