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Author: Xin Liu

Rankings

  • All-time downloads: 67,639 (rank: 2,660 )
  • Categories:
    • biochemistry: 763 (rank: 8,986 (tie) )
    • bioengineering: 550 (rank: 8,622 (tie) )
    • bioinformatics: 23,458 (rank: 160 )
    • cancer biology: 2,052 (rank: 3,686 (tie) )
    • cell biology: 178 (rank: 41,307 (tie) )
    • epidemiology: 2,403 (rank: 5,911 (tie) )
    • genetic and genomic medicine: 210 (rank: 11,981 (tie) )
    • genetics: 2,047 (rank: 9,640 )
    • genomics: 16,982 (rank: 946 )
    • immunology: 1,645 (rank: 7,893 (tie) )
    • infectious diseases: 4,010 (rank: 11,778 (tie) )
    • microbiology: 146 (rank: 63,923 (tie) )
    • molecular biology: 5,541 (rank: 635 )
    • neuroscience: 2,262 (rank: 11,620 (tie) )
    • pediatrics: 628 (rank: 974 (tie) )
    • pharmacology and toxicology: 1,850 (rank: 644 )
    • plant biology: 1,702 (rank: 2,229 )
    • systems biology: 1,212 (rank: 4,162 (tie) )

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Preprints

E-Cannula reveals anatomical diversity in sharp-wave ripples as a driver for the recruitment of distinct hippocampal assemblies

neuroscience more details view paper

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Diversity, function and evolution of marine microbe genomes

microbiology more details view paper

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Decoding of cortex-wide brain activity from local recordings of neural potentials

neuroscience more details view paper

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Potential inhibitors for 2019-nCoV coronavirus M protease from clinically approved medicines

bioinformatics more details view paper
  • Downloaded 15,525 times
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    • Site-wide: 584
    • In bioinformatics: 16
  • Year to date:
    • Site-wide: 12,529
  • Since beginning of last month:
    • Site-wide: 23,665

Chromosome level draft genomes of the fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), an alien invasive pest in China

genomics more details view paper
  • Downloaded 2,906 times
  • Download rankings, all-time:
    • Site-wide: 5,531
    • In genomics: 553
  • Year to date:
    • Site-wide: 14,704
  • Since beginning of last month:
    • Site-wide: 14,486

The Effects of "Fangcang, Huoshenshan, and Leishenshan" Makeshift Hospitals and Temperature on the Mortality of COVID-19

infectious diseases more details view paper
  • Downloaded 2,631 times
  • Download rankings, all-time:
    • Site-wide: 6,380
    • In infectious diseases: 1,107
  • Year to date:
    • Site-wide: 31,599
  • Since beginning of last month:
    • Site-wide: 40,933

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

genomics more details view paper
  • Downloaded 2,570 times
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    • Site-wide: 6,597
    • In genomics: 677
  • Year to date:
    • Site-wide: 112,626
  • Since beginning of last month:
    • Site-wide: 143,274

Dissecting super-enhancer hierarchy based on chromatin interactions

bioinformatics more details view paper
  • Downloaded 2,023 times
  • Download rankings, all-time:
    • Site-wide: 9,330
    • In bioinformatics: 1,053
  • Year to date:
    • Site-wide: 117,027
  • Since beginning of last month:
    • Site-wide: 142,106

Interrogation of Enhancer Function by Enhanced CRISPR Epigenetic Editing

molecular biology more details view paper
  • Downloaded 1,839 times
  • Download rankings, all-time:
    • Site-wide: 10,782
    • In molecular biology: 283
  • Year to date:
    • Site-wide: 54,887
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    • Site-wide: 62,471

Spatial RNA proximities reveal a bipartite nuclear transcriptome and territories of differential density and transcription elongation rates

molecular biology more details view paper
  • Downloaded 1,577 times
  • Download rankings, all-time:
    • Site-wide: 13,459
    • In molecular biology: 367
  • Year to date:
    • Site-wide: 119,983
  • Since beginning of last month:
    • Site-wide: 105,260

Single cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

neuroscience more details view paper
  • Downloaded 1,469 times
  • Download rankings, all-time:
    • Site-wide: 15,092
    • In neuroscience: 1,680
  • Year to date:
    • Site-wide: 25,471
  • Since beginning of last month:
    • Site-wide: 58,935

Systemic corticosteroids show no benefit in severe and critical COVID-19 patients in Wuhan, China: A retrospective cohort study

infectious diseases more details view paper
  • Downloaded 1,379 times
  • Download rankings, all-time:
    • Site-wide: 16,601
    • In infectious diseases: 1,839
  • Year to date:
    • Site-wide: 28,575
  • Since beginning of last month:
    • Site-wide: 30,520

Circularization of genes and chromosome by CRISPR in human cells

genomics more details view paper
  • Downloaded 1,373 times
  • Download rankings, all-time:
    • Site-wide: 16,724
    • In genomics: 1,627
  • Year to date:
    • Site-wide: 81,467
  • Since beginning of last month:
    • Site-wide: 83,801

Benchmarking Deep Learning Models and Automated Model Design for COVID-19 Detection with Chest CT Scans

epidemiology more details view paper
  • Downloaded 1,339 times
  • Download rankings, all-time:
    • Site-wide: 17,345
    • In epidemiology: 1,159
  • Year to date:
    • Site-wide: 11,143
  • Since beginning of last month:
    • Site-wide: 12,879

Initial data release and announcement of the Fish10K: Fish 10,000 Genomes Project

genomics more details view paper
  • Downloaded 1,319 times
  • Download rankings, all-time:
    • Site-wide: 17,726
    • In genomics: 1,713
  • Year to date:
    • Site-wide: 44,809
  • Since beginning of last month:
    • Site-wide: 56,154

TGS-GapCloser: fast and accurately passing through the Bermuda in large genome using error-prone third-generation long reads

bioinformatics more details view paper
  • Downloaded 1,281 times
  • Download rankings, all-time:
    • Site-wide: 18,511
    • In bioinformatics: 2,103
  • Year to date:
    • Site-wide: 21,561
  • Since beginning of last month:
    • Site-wide: 46,603

Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

systems biology more details view paper
  • Downloaded 1,212 times
  • Download rankings, all-time:
    • Site-wide: 20,117
    • In systems biology: 376
  • Year to date:
    • Site-wide: 37,547
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    • Site-wide: 52,673

Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis

molecular biology more details view paper
  • Downloaded 1,101 times
  • Download rankings, all-time:
    • Site-wide: 23,157
    • In molecular biology: 616
  • Year to date:
    • Site-wide: 48,484
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    • Site-wide: 67,000

Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study

epidemiology more details view paper
  • Downloaded 1,064 times
  • Download rankings, all-time:
    • Site-wide: 24,410
    • In epidemiology: 1,457
  • Year to date:
    • Site-wide: 55,529
  • Since beginning of last month:
    • Site-wide: 72,298

Three genomes of Osteoglossidae shed light on ancient teleost evolution

genomics more details view paper
  • Downloaded 911 times
  • Download rankings, all-time:
    • Site-wide: 30,612
    • In genomics: 2,654
  • Year to date:
    • Site-wide: 81,104
  • Since beginning of last month:
    • Site-wide: 62,681

Haplotype-Resolved Assembly for Synthetic Long Reads Using a Trio-Binning Strategy

bioinformatics more details view paper
  • Downloaded 908 times
  • Download rankings, all-time:
    • Site-wide: 30,753
    • In bioinformatics: 3,406
  • Year to date:
    • Site-wide: 34,534
  • Since beginning of last month:
    • Site-wide: 42,471

B7-H1(PD-L1) confers chemoresistance through ERK and p38 MAPK pathway in tumor cells

cancer biology more details view paper
  • Downloaded 900 times
  • Download rankings, all-time:
    • Site-wide: 31,165
    • In cancer biology: 805
  • Year to date:
    • Site-wide: 85,730
  • Since beginning of last month:
    • Site-wide: 85,458

Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia

cancer biology more details view paper
  • Downloaded 892 times
  • Download rankings, all-time:
    • Site-wide: 31,578
    • In cancer biology: 830
  • Year to date:
    • Site-wide: 14,365
  • Since beginning of last month:
    • Site-wide: 9,741

Intratumor Heterogeneity and Evolution of Colorectal Cancer

genetics more details view paper
  • Downloaded 864 times
  • Download rankings, all-time:
    • Site-wide: 33,034
    • In genetics: 1,469
  • Year to date:
    • Site-wide: 48,052
  • Since beginning of last month:
    • Site-wide: 55,856

All-Assay-Max2 pQSAR: Activity predictions as accurate as 4-concentration IC50s for 8,558 Novartis assays

bioinformatics more details view paper
  • Downloaded 862 times
  • Download rankings, all-time:
    • Site-wide: 33,161
    • In bioinformatics: 3,636
  • Year to date:
    • Site-wide: 65,483
  • Since beginning of last month:
    • Site-wide: 84,882

Infected macrophages engage alveolar epithelium to metabolically reprogram myeloid cells and promote antibacterial inflammation

immunology more details view paper
  • Downloaded 808 times
  • Download rankings, all-time:
    • Site-wide: 36,327
    • In immunology: 1,172
  • Year to date:
    • Site-wide: 30,675
  • Since beginning of last month:
    • Site-wide: 23,711

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

genomics more details view paper
  • Downloaded 800 times
  • Download rankings, all-time:
    • Site-wide: 36,785
    • In genomics: 3,048
  • Year to date:
    • Site-wide: 101,805
  • Since beginning of last month:
    • Site-wide: 83,519

SLR-superscaffolder: a de novo scaffolding tool for synthetic long reads using a top-to-bottom scheme

bioinformatics more details view paper
  • Downloaded 782 times
  • Download rankings, all-time:
    • Site-wide: 38,067
    • In bioinformatics: 4,075
  • Year to date:
    • Site-wide: 63,582
  • Since beginning of last month:
    • Site-wide: 115,918

Draft genome sequence of the Solanum aethiopicum provides insights into disease resistance, drought tolerance and the evolution of the genome

genomics more details view paper
  • Downloaded 764 times
  • Download rankings, all-time:
    • Site-wide: 39,340
    • In genomics: 3,192
  • Year to date:
    • Site-wide: 120,424
  • Since beginning of last month:
    • Site-wide: 125,440

Comparative analyses of 3654 chloroplast genomes unraveled new insights into the evolutionary mechanism of green plants

plant biology more details view paper
  • Downloaded 741 times
  • Download rankings, all-time:
    • Site-wide: 40,991
    • In plant biology: 833
  • Year to date:
    • Site-wide: 76,121
  • Since beginning of last month:
    • Site-wide: 83,319

Artesunate interacts with Vitamin D receptor to reverse mouse model of sepsis-induced immunosuppression via enhancing autophagy

pharmacology and toxicology more details view paper
  • Downloaded 740 times
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    • Site-wide: 41,087
    • In pharmacology and toxicology: 233
  • Year to date:
    • Site-wide: 40,885
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    • Site-wide: 31,802

The rise and fall of the photoinhibition-related energy dissipation qI

plant biology more details view paper
  • Downloaded 729 times
  • Download rankings, all-time:
    • Site-wide: 41,913
    • In plant biology: 860
  • Year to date:
    • Site-wide: 7,307
  • Since beginning of last month:
    • Site-wide: 12,074

Sequencing of Panax notoginseng genome reveals genes involved in disease resistance and ginsenoside biosynthesis

genomics more details view paper
  • Downloaded 722 times
  • Download rankings, all-time:
    • Site-wide: 42,458
    • In genomics: 3,399
  • Year to date:
    • Site-wide: 76,128
  • Since beginning of last month:
    • Site-wide: 63,500

Detection and characterization of copy number variants based on whole-genome sequencing by DNBSEQ platforms

bioinformatics more details view paper
  • Downloaded 702 times
  • Download rankings, all-time:
    • Site-wide: 44,129
    • In bioinformatics: 4,638
  • Year to date:
    • Site-wide: 62,214
  • Since beginning of last month:
    • Site-wide: 58,695

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

genomics more details view paper
  • Downloaded 693 times
  • Download rankings, all-time:
    • Site-wide: 44,939
    • In genomics: 3,525
  • Year to date:
    • Site-wide: 102,912
  • Since beginning of last month:
    • Site-wide: 98,327

Genome-wide Association Study for Number of Vertebrae in an F2 Large White × Minzhu Population of Pigs

genetics more details view paper
  • Downloaded 683 times
  • Download rankings, all-time:
    • Site-wide: 45,831
    • In genetics: 2,003
  • Year to date:
    • Site-wide: 131,989
  • Since beginning of last month:
    • Site-wide: 110,347

Harnessing the Cross-talk between Tumor Cells and Tumor-associated Macrophages with a Nano-drug for modulation of Glioblastoma Immune Microenvironment

pharmacology and toxicology more details view paper
  • Downloaded 660 times
  • Download rankings, all-time:
    • Site-wide: 47,946
    • In pharmacology and toxicology: 281
  • Year to date:
    • Site-wide: 66,152
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    • Site-wide: 74,103

De novo assembly of the Mongolian gerbil genome and transcriptome

genomics more details view paper
  • Downloaded 644 times
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    • Site-wide: 49,414
    • In genomics: 3,804
  • Year to date:
    • Site-wide: 109,615
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    • Site-wide: 139,693

Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial

pediatrics more details view paper
  • Downloaded 628 times
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    • Site-wide: 51,102
    • In pediatrics: 80
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    • Site-wide: 17,391
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    • Site-wide: 29,531

Genomic analyses reveal the origin of domestic ducks and identify different genetic underpinnings of wild ducks

genomics more details view paper
  • Downloaded 608 times
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    • Site-wide: 53,382
    • In genomics: 4,001
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    • Site-wide: 50,351
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    • Site-wide: 35,681

Chromosome-level genome assembly of a butterflyfish, Chelmon rostratus

genomics more details view paper
  • Downloaded 601 times
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    • Site-wide: 54,133
    • In genomics: 4,042
  • Year to date:
    • Site-wide: 88,574
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    • Site-wide: 99,295

Genome‑wide Identification and Characterization of Transcription Factors of Basic Leucine Zipper Family in Malus domestica

bioinformatics more details view paper
  • Downloaded 593 times
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    • Site-wide: 54,976
    • In bioinformatics: 5,508
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    • Site-wide: 109,924
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    • Site-wide: 112,562

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells

genomics more details view paper
  • Downloaded 524 times
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    • Site-wide: 63,895
    • In genomics: 4,546
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    • Site-wide: 137,677
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    • Site-wide: 149,572

A biophysical computational model for memory trace transfer from hippocampus to neocortex

neuroscience more details view paper
  • Downloaded 519 times
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    • Site-wide: 64,636
    • In neuroscience: 9,336
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    • Site-wide: 109,674
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    • Site-wide: 150,978

Integrated multi-omics analysis to study the effects of simulated weightlessness on rhesus macaques (Macaca mulatta)

immunology more details view paper
  • Downloaded 506 times
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    • Site-wide: 66,461
    • In immunology: 2,030
  • Year to date:
    • Site-wide: 120,019
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    • Site-wide: 113,015

A chromosome-level assembly of the Atlantic herring – detection of a supergene and other signals of selection

genomics more details view paper
  • Downloaded 504 times
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    • Site-wide: 66,802
    • In genomics: 4,692
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    • Site-wide: 124,743
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    • Site-wide: 144,937

Draft genome of a porcupinefish, Diodon Holocanthus

genomics more details view paper
  • Downloaded 450 times
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    • Site-wide: 75,585
    • In genomics: 5,079
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    • Site-wide: 95,950
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    • Site-wide: 62,701

A Proteomic Platform to Identify Off-Target Proteins Associated with Therapeutic Modalities that Induce Protein Degradation or Gene Silencing

pharmacology and toxicology more details view paper
  • Downloaded 450 times
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    • Site-wide: 75,542
    • In pharmacology and toxicology: 486
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    • Site-wide: 35,031
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    • Site-wide: 95,333

Complete chloroplast genomes of 14 mangroves: phylogenetic and genomic comparative analyses

genomics more details view paper
  • Downloaded 429 times
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    • Site-wide: 79,421
    • In genomics: 5,261
  • Year to date:
    • Site-wide: 90,286
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    • Site-wide: 103,731

Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population

genetics more details view paper
  • Downloaded 402 times
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    • Site-wide: 84,726
    • In genetics: 3,613
  • Year to date:
    • Site-wide: 123,340
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    • Site-wide: 121,225

Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia

molecular biology more details view paper
  • Downloaded 395 times
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    • Site-wide: 86,026
    • In molecular biology: 2,540
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    • Site-wide: 133,084
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    • Site-wide: 135,595

A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase

molecular biology more details view paper
  • Downloaded 392 times
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    • Site-wide: 86,785
    • In molecular biology: 2,558
  • Year to date:
    • Site-wide: 18,553
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    • Site-wide: 11,790

Slicing the genome of star-fruit (Averrhoa carambola L.)

genomics more details view paper
  • Downloaded 363 times
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    • Site-wide: 92,798
    • In genomics: 5,812
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    • Site-wide: 129,267
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    • Site-wide: 102,624

Kinetic mechanism of human mitochondrial RNase P

biochemistry more details view paper
  • Downloaded 358 times
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    • Site-wide: 93,965
    • In biochemistry: 2,709
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    • Site-wide: 104,639
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    • Site-wide: 130,770

Actin clearance promotes polarized dynein accumulation at the immunological synapse

immunology more details view paper
  • Downloaded 331 times
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    • Site-wide: 100,280
    • In immunology: 3,004
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    • Site-wide: 154,156
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    • Site-wide: 114,315

Symbiont-Screener: a reference-free filter to automatically separate host sequences and contaminants for long reads or co-barcoded reads by unsupervised clustering

bioinformatics more details view paper
  • Downloaded 329 times
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    • Site-wide: 100,775
    • In bioinformatics: 8,642
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    • Site-wide: 43,296
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    • Site-wide: 89,914

Identification of pathogenic missense mutations using protein stability predictors

bioinformatics more details view paper
  • Downloaded 324 times
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    • Site-wide: 101,907
    • In bioinformatics: 8,726
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    • Site-wide: 132,930

Nonlinear Dispersive Cell Model for Microdosimetry of Nanosecond Pulsed Electric Fields

bioengineering more details view paper
  • Downloaded 305 times
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    • Site-wide: 106,577
    • In bioengineering: 2,075
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    • Site-wide: 146,356
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    • Site-wide: 104,991

Draft Genomes of two Artocarpus plants, Jackfruit (A. heterophyllus) and Breadfruit (A. altilis)

genomics more details view paper
  • Downloaded 285 times
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    • Site-wide: 111,507
    • In genomics: 6,442
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    • Site-wide: 142,561
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    • Site-wide: 138,245

Chromosome-level genome assembly of the African pike, Hepsetus odoe

genomics more details view paper
  • Downloaded 277 times
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    • Site-wide: 113,791
    • In genomics: 6,509
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    • Site-wide: 85,937
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Comparative analysis of clonal evolution among patients with right-sided colon cancer, left-sided colon cancer and rectal cancer

cancer biology more details view paper
  • Downloaded 260 times
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    • Site-wide: 118,162
    • In cancer biology: 3,612
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    • Site-wide: 105,871
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Structural and biochemical characterization on the cognate and heterologous interactions of the MazEF-mt9 TA system

biochemistry more details view paper
  • Downloaded 259 times
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    • Site-wide: 118,478
    • In biochemistry: 3,529
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A novel method for generating 3D constructs with branched vascular networks using multi-materials bioprinting and direct surgical anastomosis

bioengineering more details view paper
  • Downloaded 245 times
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    • Site-wide: 122,160
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The genome of Mekong tiger perch (Datnioides undecimradiatus) provides insights into the phylogenic position of Lobotiformes and biological conservation

genomics more details view paper
  • Downloaded 239 times
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    • Site-wide: 123,688
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    • Site-wide: 94,543

Phylogenomics provides new insights into gains and losses of selenoproteins among Archaeplastida

molecular biology more details view paper
  • Downloaded 237 times
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    • Site-wide: 124,287
    • In molecular biology: 3,698
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    • Site-wide: 157,373
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    • Site-wide: 151,055

The complete plastid genomes of four species from Brassicales

plant biology more details view paper
  • Downloaded 232 times
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    • Site-wide: 125,492
    • In plant biology: 3,475
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    • Site-wide: 154,153
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    • Site-wide: 149,491

A Proteogenomic Signature of Age-related Macular Degeneration in Blood

genetic and genomic medicine more details view paper
  • Downloaded 210 times
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    • Site-wide: 131,303
    • In genetic and genomic medicine: 735
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Elevated Neuropeptide Y1 Receptor Signaling Contributes to β-cell Dysfunction and Failure in Type 2 Diabetes

cell biology more details view paper
  • Downloaded 178 times
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Microglial ablation does not affect opioid-induced hyperalgesia in rodents

neuroscience more details view paper
  • Downloaded 153 times
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    • In neuroscience: 21,582
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    • Site-wide: 60,737
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Blocking a dead-end assembly pathway creates a point of regulation for the DEAD-box ATPase Has1 and prevents platform misassembly

biochemistry more details view paper
  • Downloaded 146 times
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Sequencing of clinical samples reveals that adaptation keeps establishing during H7N9 virus infection in humans

microbiology more details view paper
  • Downloaded 146 times
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