Author: Eric S Lander

Downloads per author, site-wide

Preprints

The Human Cell Atlas

• Downloaded 12,232 times
• Download rankings, all-time:
  • Site-wide: 168 out of 88,847
  • In cell biology: 3 out of 4,553
• Year to date:
  • Site-wide: 5,356 out of 88,847
• Since beginning of last month:
  • Site-wide: 10,014 out of 88,847

Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming.

• Downloaded 11,298 times
• Download rankings, all-time:
  • Site-wide: 201 out of 88,847
  • In bioinformatics: 23 out of 8,398
• Year to date:
  • Site-wide: 4,308 out of 88,847
• Since beginning of last month:
  • Site-wide: 9,831 out of 88,847

Activity-by-Contact model of enhancer specificity from thousands of CRISPR perturbations

• Downloaded 8,725 times
• Download rankings, all-time:
  • Site-wide: 297 out of 88,847
  • In genetics: 23 out of 4,603
• Year to date:
  • Site-wide: 1,649 out of 88,847
• Since beginning of last month:
  • Site-wide: 2,679 out of 88,847

New mutations, old statistical challenges

• Downloaded 6,974 times
• Download rankings, all-time:
  • Site-wide: 426 out of 88,847
  • In genetics: 33 out of 4,603
• Year to date:
  • Site-wide: 32,400 out of 88,847
• Since beginning of last month:
  • Site-wide: 21,040 out of 88,847

Cohesin Loss Eliminates All Loop Domains, Leading To Links Among Superenhancers And Downregulation Of Nearby Genes

• Downloaded 4,962 times
• Download rankings, all-time:
  • Site-wide: 756 out of 88,847
  • In genomics: 153 out of 5,669
• Year to date:
  • Site-wide: 45,006 out of 88,847
• Since beginning of last month:
  • Site-wide: 85,763 out of 88,847

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

• Downloaded 4,641 times
• Download rankings, all-time:
  • Site-wide: 859 out of 88,847
  • In molecular biology: 25 out of 3,004
• Year to date:
  • Site-wide: 18,276 out of 88,847
• Since beginning of last month:
  • Site-wide: 23,138 out of 88,847

Composite measurements and molecular compressed sensing for highly efficient transcriptomics

• Downloaded 3,222 times
• Download rankings, all-time:
  • Site-wide: 1,613 out of 88,847
  • In systems biology: 37 out of 2,305
• Year to date:
  • Site-wide: 41,436 out of 88,847
• Since beginning of last month:
  • Site-wide: 46,085 out of 88,847

Mapping and characterization of structural variation in 17,795 deeply sequenced human genomes

• Downloaded 3,117 times
• Download rankings, all-time:
  • Site-wide: 1,705 out of 88,847
  • In genomics: 346 out of 5,669
• Year to date:
  • Site-wide: 1,898 out of 88,847
• Since beginning of last month:
  • Site-wide: 1,920 out of 88,847

Neighborhood regulation by lncRNA promoters, transcription, and splicing

• Downloaded 2,755 times
• Download rankings, all-time:
  • Site-wide: 2,116 out of 88,847
  • In molecular biology: 69 out of 3,004
• Year to date:
  • Site-wide: 70,188 out of 88,847
• Since beginning of last month:
  • Site-wide: 75,635 out of 88,847

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

• Downloaded 2,053 times
• Download rankings, all-time:
  • Site-wide: 3,473 out of 88,847
  • In genomics: 632 out of 5,669
• Year to date:
  • Site-wide: 65,313 out of 88,847
• Since beginning of last month:
  • Site-wide: 41,646 out of 88,847

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 1,920 times
• Download rankings, all-time:
  • Site-wide: 3,868 out of 88,847
  • In genomics: 689 out of 5,669
• Year to date:
  • Site-wide: 1,591 out of 88,847
• Since beginning of last month:
  • Site-wide: 1,873 out of 88,847

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

• Downloaded 1,833 times
• Download rankings, all-time:
  • Site-wide: 4,185 out of 88,847
  • In genetics: 310 out of 4,603
• Year to date:
  • Site-wide: 10,779 out of 88,847
• Since beginning of last month:
  • Site-wide: 22,387 out of 88,847

Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

• Downloaded 1,648 times
• Download rankings, all-time:
  • Site-wide: 4,985 out of 88,847
  • In microbiology: 302 out of 7,641
• Year to date:
  • Site-wide: 15,081 out of 88,847
• Since beginning of last month:
  • Site-wide: 21,948 out of 88,847

Applying CRISPR-based genetic screens to identify drivers of tumor-cell sensitivity towards NK-cell attack

• Downloaded 1,616 times
• Download rankings, all-time:
  • Site-wide: 5,144 out of 88,847
  • In immunology: 133 out of 2,554
• Year to date:
  • Site-wide: 6,431 out of 88,847
• Since beginning of last month:
  • Site-wide: 7,902 out of 88,847

Compressed sensing for imaging transcriptomics

• Downloaded 1,533 times
• Download rankings, all-time:
  • Site-wide: 5,625 out of 88,847
  • In molecular biology: 188 out of 3,004
• Year to date:
  • Site-wide: 5,923 out of 88,847
• Since beginning of last month:
  • Site-wide: 13,176 out of 88,847

Defining the core essential genome of Pseudomonas aeruginosa

• Downloaded 1,305 times
• Download rankings, all-time:
  • Site-wide: 7,336 out of 88,847
  • In microbiology: 437 out of 7,641
• Year to date:
  • Site-wide: 24,828 out of 88,847
• Since beginning of last month:
  • Site-wide: 16,279 out of 88,847

CRISPR-SURF: Discovering regulatory elements by deconvolution of CRISPR tiling screen data

• Downloaded 1,304 times
• Download rankings, all-time:
  • Site-wide: 7,341 out of 88,847
  • In bioinformatics: 1,292 out of 8,398
• Year to date:
  • Site-wide: 29,153 out of 88,847
• Since beginning of last month:
  • Site-wide: 33,005 out of 88,847

HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes

• Downloaded 1,208 times
• Download rankings, all-time:
  • Site-wide: 8,346 out of 88,847
  • In genomics: 1,264 out of 5,669
• Year to date:
  • Site-wide: 1,056 out of 88,847
• Since beginning of last month:
  • Site-wide: 91 out of 88,847

The Hi-Culfite assay reveals relationships between chromatin contacts and DNA methylation state

• Downloaded 1,079 times
• Download rankings, all-time:
  • Site-wide: 10,052 out of 88,847
  • In genomics: 1,475 out of 5,669
• Year to date:
  • Site-wide: 34,214 out of 88,847
• Since beginning of last month:
  • Site-wide: 47,294 out of 88,847

Discovery of cancer driver genes based on nucleotide context

• Downloaded 1,051 times
• Download rankings, all-time:
  • Site-wide: 10,490 out of 88,847
  • In genetics: 710 out of 4,603
• Year to date:
  • Site-wide: 15,301 out of 88,847
• Since beginning of last month:
  • Site-wide: 17,172 out of 88,847

The Genetic Landscape of Diamond-Blackfan Anemia

• Downloaded 1,050 times
• Download rankings, all-time:
  • Site-wide: 10,507 out of 88,847
  • In genetics: 713 out of 4,603
• Year to date:
  • Site-wide: 45,105 out of 88,847
• Since beginning of last month:
  • Site-wide: 39,022 out of 88,847

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

• Downloaded 724 times
• Download rankings, all-time:
  • Site-wide: 18,740 out of 88,847
  • In genetics: 1,192 out of 4,603
• Year to date:
  • Site-wide: 69,995 out of 88,847
• Since beginning of last month:
  • Site-wide: 47,742 out of 88,847

Delivery mode impacts newborn gut colonization efficiency

• Downloaded 627 times
• Download rankings, all-time:
  • Site-wide: 23,164 out of 88,847
  • In microbiology: 1,452 out of 7,641
• Year to date:
  • Site-wide: 2,757 out of 88,847
• Since beginning of last month:
  • Site-wide: 13,721 out of 88,847

The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research

• Downloaded 586 times
• Download rankings, all-time:
  • Site-wide: 25,507 out of 88,847
  • In cancer biology: 799 out of 3,128
• Year to date:
  • Site-wide: 16,269 out of 88,847
• Since beginning of last month:
  • Site-wide: 15,455 out of 88,847