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Author: Eric S Lander

  • Most recently observed institution: Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biology, MIT, Cambridge, MA, USA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA

Rankings

  • All-time downloads: 125,326 (rank: 1,360 )
  • Categories:
    • bioinformatics: 13,840 (rank: 646 )
    • cancer biology: 1,718 (rank: 5,992 (tie) )
    • cell biology: 13,003 (rank: 337 (tie) )
    • genetic and genomic medicine: 13,448 (rank: 34 )
    • genetics: 28,152 (rank: 280 )
    • genomics: 18,490 (rank: 847 )
    • immunology: 2,488 (rank: 6,099 (tie) )
    • microbiology: 8,058 (rank: 2,531 )
    • molecular biology: 10,603 (rank: 274 )
    • public and global health: 8,044 (rank: 771 (tie) )
    • systems biology: 3,471 (rank: 1,453 (tie) )

Downloads per author, site-wide

Preprints

The Human Cell Atlas

cell biology more details view paper
  • Downloaded 13,150 times
  • Download rankings, all-time:
    • Site-wide: 915
    • In cell biology: 8
  • Year to date:
    • Site-wide: 25,783
  • Since beginning of last month:
    • Site-wide: 43,073

Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming.

bioinformatics more details view paper
  • Downloaded 12,491 times
  • Download rankings, all-time:
    • Site-wide: 985
    • In bioinformatics: 36
  • Year to date:
    • Site-wide: 22,139
  • Since beginning of last month:
    • Site-wide: 59,000

Activity-by-Contact model of enhancer specificity from thousands of CRISPR perturbations

genetics more details view paper
  • Downloaded 10,044 times
  • Download rankings, all-time:
    • Site-wide: 1,295
    • In genetics: 25
  • Year to date:
    • Site-wide: 20,230
  • Since beginning of last month:
    • Site-wide: 33,596

Polygenic background modifies penetrance of monogenic variants conferring risk for coronary artery disease, breast cancer, or colorectal cancer

genetic and genomic medicine more details view paper
  • Downloaded 8,221 times
  • Download rankings, all-time:
    • Site-wide: 1,670
    • In genetic and genomic medicine: 8
  • Year to date:
    • Site-wide: 34,835
  • Since beginning of last month:
    • Site-wide: 41,888

Comparison of viral levels in individuals with or without symptoms at time of COVID-19 testing among 32,480 residents and staff of nursing homes and assisted living facilities in Massachusetts.

public and global health more details view paper
  • Downloaded 8,167 times
  • Download rankings, all-time:
    • Site-wide: 1,685
    • In public and global health: 66
  • Year to date:
    • Site-wide: 23,015
  • Since beginning of last month:
    • Site-wide: 41,181

New mutations, old statistical challenges

genetics more details view paper
  • Downloaded 7,295 times
  • Download rankings, all-time:
    • Site-wide: 1,939
    • In genetics: 44
  • Year to date:
    • Site-wide: 136,234
  • Since beginning of last month:
    • Site-wide: None

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

genetic and genomic medicine more details view paper
  • Downloaded 6,559 times
  • Download rankings, all-time:
    • Site-wide: 2,250
    • In genetic and genomic medicine: 12
  • Year to date:
    • Site-wide: 911
  • Since beginning of last month:
    • Site-wide: 851

Cohesin Loss Eliminates All Loop Domains, Leading To Links Among Superenhancers And Downregulation Of Nearby Genes

genomics more details view paper
  • Downloaded 5,208 times
  • Download rankings, all-time:
    • Site-wide: 3,080
    • In genomics: 251
  • Year to date:
    • Site-wide: 81,766
  • Since beginning of last month:
    • Site-wide: 86,887

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

molecular biology more details view paper
  • Downloaded 4,908 times
  • Download rankings, all-time:
    • Site-wide: 3,324
    • In molecular biology: 59
  • Year to date:
    • Site-wide: 99,460
  • Since beginning of last month:
    • Site-wide: 85,778

Mapping and characterization of structural variation in 17,795 deeply sequenced human genomes

genomics more details view paper
  • Downloaded 4,318 times
  • Download rankings, all-time:
    • Site-wide: 3,942
    • In genomics: 347
  • Year to date:
    • Site-wide: 46,231
  • Since beginning of last month:
    • Site-wide: 49,846

Composite measurements and molecular compressed sensing for highly efficient transcriptomics

systems biology more details view paper
  • Downloaded 3,510 times
  • Download rankings, all-time:
    • Site-wide: 5,331
    • In systems biology: 68
  • Year to date:
    • Site-wide: 105,370
  • Since beginning of last month:
    • Site-wide: 101,069

Genome-wide maps of enhancer regulation connect risk variants to disease genes

genetics more details view paper
  • Downloaded 3,462 times
  • Download rankings, all-time:
    • Site-wide: 5,449
    • In genetics: 181
  • Year to date:
    • Site-wide: 40,747
  • Since beginning of last month:
    • Site-wide: 47,095

A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells

microbiology more details view paper
  • Downloaded 3,433 times
  • Download rankings, all-time:
    • Site-wide: 5,519
    • In microbiology: 347
  • Year to date:
    • Site-wide: 63,227
  • Since beginning of last month:
    • Site-wide: 51,449

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 3,419 times
  • Download rankings, all-time:
    • Site-wide: 5,554
    • In genomics: 498
  • Year to date:
    • Site-wide: 37,802
  • Since beginning of last month:
    • Site-wide: 68,557

Compressed sensing for imaging transcriptomics

molecular biology more details view paper
  • Downloaded 2,974 times
  • Download rankings, all-time:
    • Site-wide: 6,805
    • In molecular biology: 145
  • Year to date:
    • Site-wide: 36,755
  • Since beginning of last month:
    • Site-wide: 24,432

Neighborhood regulation by lncRNA promoters, transcription, and splicing

molecular biology more details view paper
  • Downloaded 2,915 times
  • Download rankings, all-time:
    • Site-wide: 7,016
    • In molecular biology: 140
  • Year to date:
    • Site-wide: 163,780
  • Since beginning of last month:
    • Site-wide: 147,820

Applying CRISPR-based genetic screens to identify drivers of tumor-cell sensitivity towards NK-cell attack

immunology more details view paper
  • Downloaded 2,638 times
  • Download rankings, all-time:
    • Site-wide: 8,117
    • In immunology: 297
  • Year to date:
    • Site-wide: 26,240
  • Since beginning of last month:
    • Site-wide: 36,954

Compatibility logic of human enhancer and promoter sequences

genetics more details view paper
  • Downloaded 2,575 times
  • Download rankings, all-time:
    • Site-wide: 8,393
    • In genetics: 412
  • Year to date:
    • Site-wide: 3,142
  • Since beginning of last month:
    • Site-wide: 20,735

HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes

genomics more details view paper
  • Downloaded 2,405 times
  • Download rankings, all-time:
    • Site-wide: 9,270
    • In genomics: 840
  • Year to date:
    • Site-wide: 97,482
  • Since beginning of last month:
    • Site-wide: None

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

genetics more details view paper
  • Downloaded 2,223 times
  • Download rankings, all-time:
    • Site-wide: 10,421
    • In genetics: 387
  • Year to date:
    • Site-wide: 67,011
  • Since beginning of last month:
    • Site-wide: 41,078

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

genomics more details view paper
  • Downloaded 2,151 times
  • Download rankings, all-time:
    • Site-wide: 10,970
    • In genomics: 953
  • Year to date:
    • Site-wide: 179,341
  • Since beginning of last month:
    • Site-wide: 151,250

Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

microbiology more details view paper
  • Downloaded 2,054 times
  • Download rankings, all-time:
    • Site-wide: 11,771
    • In microbiology: 640
  • Year to date:
    • Site-wide: 81,880
  • Since beginning of last month:
    • Site-wide: 126,647

Defining the core essential genome of Pseudomonas aeruginosa

microbiology more details view paper
  • Downloaded 1,587 times
  • Download rankings, all-time:
    • Site-wide: 17,362
    • In microbiology: 913
  • Year to date:
    • Site-wide: 117,667
  • Since beginning of last month:
    • Site-wide: 104,307

CRISPR-SURF: Discovering regulatory elements by deconvolution of CRISPR tiling screen data

bioinformatics more details view paper
  • Downloaded 1,515 times
  • Download rankings, all-time:
    • Site-wide: 18,628
    • In bioinformatics: 1,856
  • Year to date:
    • Site-wide: 152,174
  • Since beginning of last month:
    • Site-wide: 124,639

The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research

cancer biology more details view paper
  • Downloaded 1,445 times
  • Download rankings, all-time:
    • Site-wide: 20,115
    • In cancer biology: 461
  • Year to date:
    • Site-wide: 35,001
  • Since beginning of last month:
    • Site-wide: 32,007

The Hi-Culfite assay reveals relationships between chromatin contacts and DNA methylation state

genomics more details view paper
  • Downloaded 1,351 times
  • Download rankings, all-time:
    • Site-wide: 22,304
    • In genomics: 1,850
  • Year to date:
    • Site-wide: 100,890
  • Since beginning of last month:
    • Site-wide: 67,260

Discovery of cancer driver genes based on nucleotide context

genetics more details view paper
  • Downloaded 1,297 times
  • Download rankings, all-time:
    • Site-wide: 23,794
    • In genetics: 919
  • Year to date:
    • Site-wide: 143,947
  • Since beginning of last month:
    • Site-wide: 126,473

The Genetic Landscape of Diamond-Blackfan Anemia

genetics more details view paper
  • Downloaded 1,229 times
  • Download rankings, all-time:
    • Site-wide: 25,916
    • In genetics: 993
  • Year to date:
    • Site-wide: 126,554
  • Since beginning of last month:
    • Site-wide: 102,533

Delivery mode impacts newborn gut colonization efficiency

microbiology more details view paper
  • Downloaded 1,182 times
  • Download rankings, all-time:
    • Site-wide: 27,490
    • In microbiology: 1,470
  • Year to date:
    • Site-wide: 108,746
  • Since beginning of last month:
    • Site-wide: 189,799

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

genetics more details view paper
  • Downloaded 819 times
  • Download rankings, all-time:
    • Site-wide: 47,866
    • In genetics: 1,794
  • Year to date:
    • Site-wide: 169,725
  • Since beginning of last month:
    • Site-wide: 159,704

A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project

cancer biology more details view paper
  • Downloaded 464 times
  • Download rankings, all-time:
    • Site-wide: 100,026
    • In cancer biology: 2,969
  • Year to date:
    • Site-wide: 79,826
  • Since beginning of last month:
    • Site-wide: 53,017

Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis

genetics more details view paper
  • Downloaded 317 times
  • Download rankings, all-time:
    • Site-wide: 138,783
    • In genetics: 5,682
  • Year to date:
    • Site-wide: 52,232
  • Since beginning of last month:
    • Site-wide: 84,970

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