Author: Michel G Nivard

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Preprints

Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

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Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

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Investigating the Genetic Architecture of Non-Cognitive Skills Using GWAS-by-Subtraction

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Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

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  • Site-wide: 6,875
  • In genetics: 323
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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

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  • In genetic and genomic medicine: 38
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Stratified Linkage Disequilibrium Score Regression reveals enrichment of eQTL effects on complex traits is not tissue specific

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  • In genomics: 1,530
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Within-sibship GWAS improve estimates of direct genetic effects

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Geographic Confounding in Genome-Wide Association Studies

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Parental influences on offspring education: indirect genetic effects of non-cognitive skills

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  • Site-wide: 27,457
  • In genetics: 1,295
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Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits

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  • In genetic and genomic medicine: 102
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The genomic architecture of blood metabolites based on a decade of genome-wide analyses

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Genetic overlap between schizophrenia and developmental psychopathology: a longitudinal approach applied to common childhood disorders between age 7 and 15 years

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  • Site-wide: 52,188
  • In genetics: 2,379
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Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

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  • Site-wide: 60,330
  • In psychiatry and clinical psychology: 198
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  • Site-wide: 28,459

Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

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  • Site-wide: 66,309
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Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data: a comparison of multivariate methods

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  • Site-wide: 97,342
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Contribution of genetic and environmental factors to the onset of preclinical Alzheimer's disease - a monozygotic twin study

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  • Site-wide: 101,107
  • In neurology: 308
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Transcriptome-wide and Stratified Genomic Structural Equation Modeling Identify Neurobiological Pathways Underlying General and Specific Cognitive Functions

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  • Site-wide: 119,437
  • In genetic and genomic medicine: 589
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Multivariate Modeling of Direct and Proxy GWAS Indicates Substantial Common Variant Heritability of Alzheimer's Disease

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  • In genetic and genomic medicine: 633
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Safe linkage of cohort and population-based register data in a genome-wide association study on health care expenditure

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  • Site-wide: 127,148
  • In genetics: 5,306
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Ultra-rare, rare, and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia

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  • Site-wide: 134,994
  • In genetic and genomic medicine: 702
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