Author: Michel G Nivard

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Preprints

Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

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  • Site-wide: 1,518
  • In genetics: 32
• Year to date:
  • Site-wide: 45,989
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  • Site-wide: 25,905

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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  • Site-wide: 3,190
  • In genomics: 275
• Year to date:
  • Site-wide: 47,129
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  • Site-wide: 19,583

Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

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  • Site-wide: 3,438
  • In genetics: 95
• Year to date:
  • Site-wide: 60,385
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Investigating the Genetic Architecture of Non-Cognitive Skills Using GWAS-by-Subtraction

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  • Site-wide: 5,238
  • In genetics: 174
• Year to date:
  • Site-wide: 35,589
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Within-sibship GWAS improve estimates of direct genetic effects

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  • Site-wide: 5,438
  • In genetics: 188
• Year to date:
  • Site-wide: 2,894
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Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

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  • Site-wide: 5,647
  • In genetic and genomic medicine: 29
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  • Site-wide: 2,506
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  • Site-wide: 9,293

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

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  • Site-wide: 8,872
  • In genetics: 349
• Year to date:
  • Site-wide: 54,162
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  • Site-wide: 12,534

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

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  • Site-wide: 9,352
  • In genetics: 362
• Year to date:
  • Site-wide: 137,343
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  • Site-wide: None

Parental influences on offspring education: indirect genetic effects of non-cognitive skills

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  • Site-wide: 12,177
  • In genetics: 468
• Year to date:
  • Site-wide: 9,846
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  • Site-wide: 14,478

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 14,258
  • In genetics: 568
• Year to date:
  • Site-wide: 141,139
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  • Site-wide: 76,085

Geographic Confounding in Genome-Wide Association Studies

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  • Site-wide: 16,281
  • In genetics: 667
• Year to date:
  • Site-wide: 19,768
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Stratified Linkage Disequilibrium Score Regression reveals enrichment of eQTL effects on complex traits is not tissue specific

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  • Site-wide: 20,824
  • In genomics: 1,832
• Year to date:
  • Site-wide: 127,064
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  • Site-wide: 60,031

Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits

• Downloaded 1,063 times
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  • Site-wide: 33,433
  • In genetic and genomic medicine: 200
• Year to date:
  • Site-wide: 111,630
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  • Site-wide: 50,870

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

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  • Site-wide: 37,217
  • In psychiatry and clinical psychology: 149
• Year to date:
  • Site-wide: 38,073
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  • Site-wide: 140,562

Pervasive Downward Bias in Estimates of Liability Scale Heritability in GWAS Meta-Analysis: A Simple Solution

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  • Site-wide: 40,817
  • In genetic and genomic medicine: 257
• Year to date:
  • Site-wide: 9,840
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  • Site-wide: 13,377

Patterns of item nonresponse behavior to survey questionnaires are systematic and have a genetic basis

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  • Site-wide: 47,535
  • In genetics: 1,926
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  • Site-wide: 3,616
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  • Site-wide: 25,089

The genomic architecture of blood metabolites based on a decade of genome-wide analyses

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  • Site-wide: 53,450
  • In genetics: 2,096
• Year to date:
  • Site-wide: 158,383
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  • Site-wide: None

Transcriptome-wide and Stratified Genomic Structural Equation Modeling Identify Neurobiological Pathways Underlying General and Specific Cognitive Functions

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  • Site-wide: 64,509
  • In genetic and genomic medicine: 395
• Year to date:
  • Site-wide: 22,888
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  • Site-wide: 53,601

Multivariate Modeling of Direct and Proxy GWAS Indicates Substantial Common Variant Heritability of Alzheimer's Disease

• Downloaded 641 times
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  • Site-wide: 70,352
  • In genetic and genomic medicine: 424
• Year to date:
  • Site-wide: 36,398
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  • Site-wide: 89,906

Genetic overlap between schizophrenia and developmental psychopathology: a longitudinal approach applied to common childhood disorders between age 7 and 15 years

• Downloaded 624 times
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  • Site-wide: 72,930
  • In genetics: 2,812
• Year to date:
  • Site-wide: 166,939
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  • Site-wide: 100,613

Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

• Downloaded 585 times
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  • Site-wide: 79,067
  • In genetics: 3,077
• Year to date:
  • Site-wide: 113,608
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  • Site-wide: 141,042

Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia

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  • Site-wide: 104,515
  • In genetic and genomic medicine: 652
• Year to date:
  • Site-wide: 42,621
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  • Site-wide: 90,135

Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data: a comparison of multivariate methods

• Downloaded 422 times
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  • Site-wide: 113,796
  • In genetics: 4,310
• Year to date:
  • Site-wide: 160,273
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  • Site-wide: 150,996

Contribution of genetic and environmental factors to the onset of preclinical Alzheimer's disease - a monozygotic twin study

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  • Site-wide: 126,692
  • In neurology: 634
• Year to date:
  • Site-wide: 163,443
• Since beginning of last month:
  • Site-wide: 139,539

Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

• Downloaded 323 times
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  • Site-wide: 141,457
  • In epidemiology: 6,262
• Year to date:
  • Site-wide: 17,352
• Since beginning of last month:
  • Site-wide: 12,182

Safe linkage of cohort and population-based register data in a genome-wide association study on health care expenditure

• Downloaded 216 times
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  • Site-wide: 171,909
  • In genetics: 6,269
• Year to date:
  • Site-wide: 197,094
• Since beginning of last month:
  • Site-wide: 111,250