Author: Peter Van Loo

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Preprints

The evolutionary history of 2,658 cancers

• Downloaded 9,450 times
• Download rankings, all-time:
  • Site-wide: 798
  • In cancer biology: 8
• Year to date:
  • Site-wide: 21,606
• Since beginning of last month:
  • Site-wide: 21,606

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

• Downloaded 5,632 times
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  • Site-wide: 1,595
  • In cancer biology: 21
• Year to date:
  • Site-wide: 3,326
• Since beginning of last month:
  • Site-wide: 3,326

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours

• Downloaded 3,564 times
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  • Site-wide: 3,005
  • In genomics: 354
• Year to date:
  • Site-wide: 22,359
• Since beginning of last month:
  • Site-wide: 22,359

Mutational signatures associated with tobacco smoking in human cancer

• Downloaded 3,455 times
• Download rankings, all-time:
  • Site-wide: 3,156
  • In cancer biology: 50
• Year to date:
  • Site-wide: 95,111
• Since beginning of last month:
  • Site-wide: 95,111

Universal Patterns Of Selection In Cancer And Somatic Tissues

• Downloaded 3,329 times
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  • Site-wide: 3,326
  • In genomics: 383
• Year to date:
  • Site-wide: 119,749
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  • Site-wide: 119,749

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

• Downloaded 2,307 times
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  • Site-wide: 5,654
  • In genomics: 659
• Year to date:
  • Site-wide: 26,003
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  • Site-wide: 26,003

Neutral tumor evolution?

• Downloaded 2,052 times
• Download rankings, all-time:
  • Site-wide: 6,669
  • In cancer biology: 108
• Year to date:
  • Site-wide: 78,167
• Since beginning of last month:
  • Site-wide: 78,167

Creating Standards for Evaluating Tumour Subclonal Reconstruction

• Downloaded 1,971 times
• Download rankings, all-time:
  • Site-wide: 7,061
  • In bioinformatics: 871
• Year to date:
  • Site-wide: 43,260
• Since beginning of last month:
  • Site-wide: 43,260

Allele-specific multi-sample copy number segmentation

• Downloaded 753 times
• Download rankings, all-time:
  • Site-wide: 29,263
  • In bioinformatics: 3,367
• Year to date:
  • Site-wide: 43,280
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  • Site-wide: 43,280

An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers

• Downloaded 520 times
• Download rankings, all-time:
  • Site-wide: 47,196
  • In cancer biology: 1,323
• Year to date:
  • Site-wide: 21,489
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  • Site-wide: 21,489

Copy number-aware deconvolution of tumor-normal DNA methylation profiles

• Downloaded 515 times
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  • Site-wide: 47,796
  • In genomics: 3,831
• Year to date:
  • Site-wide: 6,954
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  • Site-wide: 6,954

Differing total mRNA expression shapes the molecular and clinical phenotype of cancer

• Downloaded 401 times
• Download rankings, all-time:
  • Site-wide: 62,703
  • In genomics: 4,567
• Year to date:
  • Site-wide: 30,753
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  • Site-wide: 30,753

A pan-cancer landscape of somatic substitutions in non-unique regions of the human genome

• Downloaded 400 times
• Download rankings, all-time:
  • Site-wide: 62,741
  • In genomics: 4,576
• Year to date:
  • Site-wide: 35,993
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  • Site-wide: 35,993

Copy number motifs expose genome instability type and predict driver events and disease outcome in breast cancer

• Downloaded 381 times
• Download rankings, all-time:
  • Site-wide: 65,785
  • In bioinformatics: 6,411
• Year to date:
  • Site-wide: 117,645
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  • Site-wide: 117,645

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

• Downloaded 233 times
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  • Site-wide: 94,404
  • In genomics: 5,783
• Year to date:
  • Site-wide: 30,626
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  • Site-wide: 30,626

Drivers underpinning the malignant transformation of giant cell tumour of bone

• Downloaded 159 times
• Download rankings, all-time:
  • Site-wide: 109,947
  • In genetic and genomic medicine: 462
• Year to date:
  • Site-wide: 59,815
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  • Site-wide: 59,815