Author: Peter Van Loo

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Preprints

The evolutionary history of 2,658 cancers

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  • In cancer biology: 6 out of 3,104
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  • Site-wide: 10,271 out of 88,402

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

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  • Site-wide: 795 out of 88,402
  • In cancer biology: 23 out of 3,104
• Year to date:
  • Site-wide: 1,831 out of 88,402
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  • Site-wide: 2,416 out of 88,402

Mutational signatures associated with tobacco smoking in human cancer

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  • Site-wide: 1,471 out of 88,402
  • In cancer biology: 38 out of 3,104
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  • Site-wide: 55,272 out of 88,402

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours

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  • In genomics: 319 out of 5,641
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  • Site-wide: 13,310 out of 88,402

Universal Patterns Of Selection In Cancer And Somatic Tissues

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  • In genomics: 328 out of 5,641
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Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

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  • In genomics: 600 out of 5,641
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  • Site-wide: 18,928 out of 88,402

Neutral tumor evolution?

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  • Site-wide: 3,603 out of 88,402
  • In cancer biology: 78 out of 3,104
• Year to date:
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  • Site-wide: 52,599 out of 88,402

Creating Standards for Evaluating Tumour Subclonal Reconstruction

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  • Site-wide: 4,172 out of 88,402
  • In bioinformatics: 767 out of 8,368
• Year to date:
  • Site-wide: 18,723 out of 88,402
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  • Site-wide: 26,431 out of 88,402

Allele-specific multi-sample copy number segmentation

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  • Site-wide: 24,033 out of 88,402
  • In bioinformatics: 3,367 out of 8,368
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  • Site-wide: 39,456 out of 88,402
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  • Site-wide: 28,736 out of 88,402

Copy number motifs expose genome instability type and predict driver events and disease outcome in breast cancer

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  • In bioinformatics: 5,480 out of 8,368
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  • Site-wide: 56,864 out of 88,402

A pan-cancer landscape of somatic substitutions in non-unique regions of the human genome

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  • Site-wide: 65,353 out of 88,402
  • In genomics: 4,826 out of 5,641
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  • Site-wide: 20,057 out of 88,402