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Author: John Danesh

  • ORCiD: http://orcid.org/0000-0003-1158-6791
  • Most recently observed institution: Cardiovascular Epidemiology Unit, Department of Public Health & Primary Care, University of Cambridge, Strangeways Research Laboratory

Rankings

  • All-time downloads: 60,921 (rank: 664 out of 426,414)
  • Categories:
    • epidemiology: 619 (rank: 3,027 (tie) out of 9,545)
    • genetics: 26,329 (rank: 213 out of 38,003)
    • genomics: 33,973 (rank: 231 out of 44,644)

Downloads per author, site-wide

Preprints

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
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    • In genomics: 10 out of 6,255
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    • Site-wide: 18,742 out of 100,936
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    • Site-wide: 24,124 out of 100,936

Consequences Of Natural Perturbations In The Human Plasma Proteome

genomics more details view paper
  • Downloaded 4,210 times
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    • In genomics: 243 out of 6,255
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  • Since beginning of last month:
    • Site-wide: 78,271 out of 100,936

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

genetics more details view paper
  • Downloaded 3,932 times
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    • In genetics: 96 out of 5,022
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    • Site-wide: 26,399 out of 100,936
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    • Site-wide: 22,963 out of 100,936

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 3,441 times
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    • In genetics: 116 out of 5,022
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    • Site-wide: 2,434 out of 100,936

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 2,985 times
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    • In genetics: 158 out of 5,022
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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

genomics more details view paper
  • Downloaded 2,285 times
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    • In genomics: 609 out of 6,255
  • Year to date:
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    • Site-wide: 10,677 out of 100,936

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

genetics more details view paper
  • Downloaded 1,986 times
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    • In genetics: 310 out of 5,022
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    • Site-wide: 905 out of 100,936
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    • Site-wide: 4,059 out of 100,936

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

genetics more details view paper
  • Downloaded 1,876 times
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    • In genetics: 335 out of 5,022
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    • Site-wide: 999 out of 100,936
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    • Site-wide: 1,699 out of 100,936

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,801 times
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    • Site-wide: 5,039 out of 100,936
    • In genetics: 356 out of 5,022
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    • Site-wide: 59,019 out of 100,936
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    • Site-wide: 71,423 out of 100,936

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

genetics more details view paper
  • Downloaded 1,773 times
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    • Site-wide: 5,161 out of 100,936
    • In genetics: 366 out of 5,022
  • Year to date:
    • Site-wide: 1,090 out of 100,936
  • Since beginning of last month:
    • Site-wide: 1,217 out of 100,936

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
  • Downloaded 1,574 times
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    • Site-wide: 6,300 out of 100,936
    • In genetics: 442 out of 5,022
  • Year to date:
    • Site-wide: 13,724 out of 100,936
  • Since beginning of last month:
    • Site-wide: 24,232 out of 100,936

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

genomics more details view paper
  • Downloaded 1,512 times
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    • Site-wide: 6,750 out of 100,936
    • In genomics: 1,042 out of 6,255
  • Year to date:
    • Site-wide: 27,128 out of 100,936
  • Since beginning of last month:
    • Site-wide: 23,163 out of 100,936

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

genetics more details view paper
  • Downloaded 1,319 times
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    • Site-wide: 8,523 out of 100,936
    • In genetics: 574 out of 5,022
  • Year to date:
    • Site-wide: 3,279 out of 100,936
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    • Site-wide: 8,754 out of 100,936

Learning polygenic scores for human blood cell traits

genetics more details view paper
  • Downloaded 1,255 times
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    • Site-wide: 9,254 out of 100,936
    • In genetics: 627 out of 5,022
  • Year to date:
    • Site-wide: 1,866 out of 100,936
  • Since beginning of last month:
    • Site-wide: 10,738 out of 100,936

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

genetics more details view paper
  • Downloaded 1,050 times
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    • Site-wide: 12,401 out of 100,936
    • In genetics: 819 out of 5,022
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    • Site-wide: 53,710 out of 100,936
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    • Site-wide: 64,460 out of 100,936

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

genomics more details view paper
  • Downloaded 983 times
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    • In genomics: 1,816 out of 6,255
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    • Site-wide: 88,816 out of 100,936
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    • Site-wide: 82,805 out of 100,936

Genetic effects on promoter usage are highly context-specific and contribute to complex traits

genomics more details view paper
  • Downloaded 970 times
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    • Site-wide: 14,095 out of 100,936
    • In genomics: 1,845 out of 6,255
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    • Site-wide: 56,690 out of 100,936

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

genomics more details view paper
  • Downloaded 969 times
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    • Site-wide: 14,121 out of 100,936
    • In genomics: 1,853 out of 6,255
  • Year to date:
    • Site-wide: 14,630 out of 100,936
  • Since beginning of last month:
    • Site-wide: 13,656 out of 100,936

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

genomics more details view paper
  • Downloaded 749 times
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    • Site-wide: 21,010 out of 100,936
    • In genomics: 2,421 out of 6,255
  • Year to date:
    • Site-wide: 50,026 out of 100,936
  • Since beginning of last month:
    • Site-wide: 51,619 out of 100,936

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

genetics more details view paper
  • Downloaded 734 times
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    • In genetics: 1,339 out of 5,022
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    • Site-wide: 71,279 out of 100,936
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    • Site-wide: 52,580 out of 100,936

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 683 times
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    • Site-wide: 24,137 out of 100,936
    • In genetics: 1,473 out of 5,022
  • Year to date:
    • Site-wide: 15,433 out of 100,936
  • Since beginning of last month:
    • Site-wide: 13,906 out of 100,936

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

epidemiology more details view paper
  • Downloaded 619 times
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    • In epidemiology: 332 out of 1,556
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    • Site-wide: 67,283 out of 100,936

Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

genetics more details view paper
  • Downloaded 595 times
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    • Site-wide: 29,231 out of 100,936
    • In genetics: 1,747 out of 5,022
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    • Site-wide: 5,777 out of 100,936
  • Since beginning of last month:
    • Site-wide: 14,900 out of 100,936

South Asian Patient Population Genetics Reveal Strong Founder Effects and High Rates of Homozygosity – New Resources for Precision Medicine

genomics more details view paper
  • Downloaded 458 times
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    • In genomics: 3,763 out of 6,255
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    • Site-wide: 599 out of 100,936

Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease

genetics more details view paper
  • Downloaded 347 times
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    • Site-wide: 54,083 out of 100,936
    • In genetics: 2,989 out of 5,022
  • Year to date:
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    • Site-wide: 43,358 out of 100,936

Interleukin-6 Receptor Signalling and Abdominal Aortic Aneurysm Growth Rates

genetics more details view paper
  • Downloaded 347 times
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    • Site-wide: 54,034 out of 100,936
    • In genetics: 2,986 out of 5,022
  • Year to date:
    • Site-wide: 69,938 out of 100,936
  • Since beginning of last month:
    • Site-wide: 67,292 out of 100,936

Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

genetics more details view paper
  • Downloaded 336 times
  • Download rankings, all-time:
    • Site-wide: 55,642 out of 100,936
    • In genetics: 3,071 out of 5,022
  • Year to date:
    • Site-wide: 84,576 out of 100,936
  • Since beginning of last month:
    • Site-wide: 91,360 out of 100,936

The influence of rare variants in circulating metabolic biomarkers

genetics more details view paper
  • Downloaded 295 times
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    • Site-wide: 61,963 out of 100,936
    • In genetics: 3,383 out of 5,022
  • Year to date:
    • Site-wide: 85,358 out of 100,936
  • Since beginning of last month:
    • Site-wide: 83,706 out of 100,936

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