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Author: Stephen Burgess

Rankings

  • All-time downloads: 51,080 (rank: 3,410 )
  • Categories:
    • bioinformatics: 738 (rank: 20,886 (tie) )
    • cardiovascular medicine: 1,475 (rank: 298 )
    • endocrinology: 47 (rank: 1,841 (tie) )
    • epidemiology: 13,429 (rank: 1,201 )
    • genetic and genomic medicine: 4,545 (rank: 343 )
    • genetics: 21,960 (rank: 441 )
    • genomics: 5,432 (rank: 4,598 (tie) )
    • neurology: 303 (rank: 4,523 (tie) )
    • oncology: 667 (rank: 1,067 (tie) )
    • psychiatry and clinical psychology: 666 (rank: 1,856 (tie) )
    • sexual and reproductive health: 1,818 (rank: 116 (tie) )

Downloads per author, site-wide

Preprints

Alcohol consumption and telomere length: observational and Mendelian randomization approaches

addiction medicine more details view paper

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Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

epidemiology more details view paper

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Consequences Of Natural Perturbations In The Human Plasma Proteome

genomics more details view paper
  • Downloaded 4,302 times
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    • Site-wide: 2,987
    • In genomics: 303
  • Year to date:
    • Site-wide: 92,314
  • Since beginning of last month:
    • Site-wide: 105,676

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 4,137 times
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    • Site-wide: 3,137
    • In epidemiology: 333
  • Year to date:
    • Site-wide: 27,663
  • Since beginning of last month:
    • Site-wide: 11,953

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 4,078 times
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    • Site-wide: 3,197
    • In genetics: 107
  • Year to date:
    • Site-wide: 10,158
  • Since beginning of last month:
    • Site-wide: 8,299

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits

genetics more details view paper
  • Downloaded 4,007 times
  • Download rankings, all-time:
    • Site-wide: 3,288
    • In genetics: 111
  • Year to date:
    • Site-wide: 12,574
  • Since beginning of last month:
    • Site-wide: 90,155

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

genetics more details view paper
  • Downloaded 2,775 times
  • Download rankings, all-time:
    • Site-wide: 5,495
    • In genetics: 228
  • Year to date:
    • Site-wide: 8,116
  • Since beginning of last month:
    • Site-wide: 119,012

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

genetics more details view paper
  • Downloaded 2,158 times
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    • Site-wide: 7,977
    • In genetics: 350
  • Year to date:
    • Site-wide: 5,448
  • Since beginning of last month:
    • Site-wide: 58,256

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 1,818 times
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    • Site-wide: 10,246
    • In sexual and reproductive health: 10
  • Year to date:
    • Site-wide: 1,519
  • Since beginning of last month:
    • Site-wide: 265

ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study

genetic and genomic medicine more details view paper
  • Downloaded 1,722 times
  • Download rankings, all-time:
    • Site-wide: 11,105
    • In genetic and genomic medicine: 46
  • Year to date:
    • Site-wide: 61,276
  • Since beginning of last month:
    • Site-wide: 72,511

Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization

genetics more details view paper
  • Downloaded 1,581 times
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    • Site-wide: 12,563
    • In genetics: 570
  • Year to date:
    • Site-wide: 73,930
  • Since beginning of last month:
    • Site-wide: None

A Comparison Of Robust Mendelian Randomization Methods Using Summary Data

epidemiology more details view paper
  • Downloaded 1,455 times
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    • Site-wide: 14,237
    • In epidemiology: 987
  • Year to date:
    • Site-wide: 26,999
  • Since beginning of last month:
    • Site-wide: 10,468

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

genomics more details view paper
  • Downloaded 1,130 times
  • Download rankings, all-time:
    • Site-wide: 20,793
    • In genomics: 1,992
  • Year to date:
    • Site-wide: 65,522
  • Since beginning of last month:
    • Site-wide: 30,906

Genome-wide association and Mendelian randomization analysis prioritizes bioactive metabolites with putative causal effects on common diseases

genetic and genomic medicine more details view paper
  • Downloaded 1,099 times
  • Download rankings, all-time:
    • Site-wide: 21,653
    • In genetic and genomic medicine: 89
  • Year to date:
    • Site-wide: 17,396
  • Since beginning of last month:
    • Site-wide: 44,860

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease

epidemiology more details view paper
  • Downloaded 1,069 times
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    • Site-wide: 22,556
    • In epidemiology: 1,361
  • Year to date:
    • Site-wide: 15,369
  • Since beginning of last month:
    • Site-wide: 94,602

A robust and efficient method for Mendelian randomization with hundreds of genetic variants: unravelling mechanisms linking HDL-cholesterol and coronary heart disease

genetics more details view paper
  • Downloaded 1,056 times
  • Download rankings, all-time:
    • Site-wide: 22,957
    • In genetics: 1,052
  • Year to date:
    • Site-wide: 86,623
  • Since beginning of last month:
    • Site-wide: 76,476

Cardiometabolic traits, sepsis and severe covid-19 with respiratory failure: a Mendelian randomization investigation

epidemiology more details view paper
  • Downloaded 939 times
  • Download rankings, all-time:
    • Site-wide: 27,269
    • In epidemiology: 1,538
  • Year to date:
    • Site-wide: 32,639
  • Since beginning of last month:
    • Site-wide: 131,145

Shared risk alleles with discordant polygenic effects: Disentangling the genetic overlap between ASD and ADHD

genetics more details view paper
  • Downloaded 870 times
  • Download rankings, all-time:
    • Site-wide: 30,316
    • In genetics: 1,388
  • Year to date:
    • Site-wide: 84,041
  • Since beginning of last month:
    • Site-wide: 111,837

Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

genetics more details view paper
  • Downloaded 858 times
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    • Site-wide: 30,984
    • In genetics: 1,421
  • Year to date:
    • Site-wide: 31,637
  • Since beginning of last month:
    • Site-wide: 116,208

Power calculator for instrumental variable analysis in pharmacoepidemiology

epidemiology more details view paper
  • Downloaded 837 times
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    • Site-wide: 32,036
    • In epidemiology: 1,700
  • Year to date:
    • Site-wide: 137,359
  • Since beginning of last month:
    • Site-wide: 58,029

Birthweight, Type 2 Diabetes and Cardiovascular Disease: Addressing the Barker Hypothesis with Mendelian randomization

genetics more details view paper
  • Downloaded 813 times
  • Download rankings, all-time:
    • Site-wide: 33,316
    • In genetics: 1,535
  • Year to date:
    • Site-wide: 81,803
  • Since beginning of last month:
    • Site-wide: 104,492

Genetically predicted serum urate, blood pressure and cardiovascular disease: an updated Mendelian randomization investigation

cardiovascular medicine more details view paper
  • Downloaded 748 times
  • Download rankings, all-time:
    • Site-wide: 37,545
    • In cardiovascular medicine: 58
  • Year to date:
    • Site-wide: 54,803
  • Since beginning of last month:
    • Site-wide: 72,304

Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language

genetics more details view paper
  • Downloaded 743 times
  • Download rankings, all-time:
    • Site-wide: 37,885
    • In genetics: 1,708
  • Year to date:
    • Site-wide: 132,395
  • Since beginning of last month:
    • Site-wide: None

Factorial Mendelian randomization: using genetic variants to assess interactions

epidemiology more details view paper
  • Downloaded 712 times
  • Download rankings, all-time:
    • Site-wide: 40,157
    • In epidemiology: 2,010
  • Year to date:
    • Site-wide: 105,093
  • Since beginning of last month:
    • Site-wide: 41,711

Dissecting causal pathways using Mendelian randomization with summarized genetic data: application to age at menarche and risk of breast cancer

epidemiology more details view paper
  • Downloaded 685 times
  • Download rankings, all-time:
    • Site-wide: 42,248
    • In epidemiology: 2,092
  • Year to date:
    • Site-wide: 115,683
  • Since beginning of last month:
    • Site-wide: 37,362

Genetic determinants of lipids and cardiovascular disease outcomes: a wide-angled Mendelian randomization investigation

epidemiology more details view paper
  • Downloaded 679 times
  • Download rankings, all-time:
    • Site-wide: 42,726
    • In epidemiology: 2,108
  • Year to date:
    • Site-wide: 72,978
  • Since beginning of last month:
    • Site-wide: 50,558

Predicting the effect of statins on cancer risk using genetic variants: a Mendelian randomization study in UK Biobank

oncology more details view paper
  • Downloaded 667 times
  • Download rankings, all-time:
    • Site-wide: 43,718
    • In oncology: 59
  • Year to date:
    • Site-wide: 82,845
  • Since beginning of last month:
    • Site-wide: 61,436

Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease

epidemiology more details view paper
  • Downloaded 603 times
  • Download rankings, all-time:
    • Site-wide: 49,751
    • In epidemiology: 2,344
  • Year to date:
    • Site-wide: 26,145
  • Since beginning of last month:
    • Site-wide: 54,841

MR-Clust: Clustering of genetic variants in Mendelian randomization with similar causal estimates

bioinformatics more details view paper
  • Downloaded 569 times
  • Download rankings, all-time:
    • Site-wide: 53,481
    • In bioinformatics: 5,403
  • Year to date:
    • Site-wide: 113,493
  • Since beginning of last month:
    • Site-wide: 108,605

Elucidating mechanisms of genetic cross-disease associations: an integrative approach implicates protein C as a causal pathway in arterial and venous diseases

genetic and genomic medicine more details view paper
  • Downloaded 557 times
  • Download rankings, all-time:
    • Site-wide: 54,923
    • In genetic and genomic medicine: 223
  • Year to date:
    • Site-wide: 56,867
  • Since beginning of last month:
    • Site-wide: 45,500

Polygenic modelling of treatment effect heterogeneity

genetic and genomic medicine more details view paper
  • Downloaded 543 times
  • Download rankings, all-time:
    • Site-wide: 56,673
    • In genetic and genomic medicine: 232
  • Year to date:
    • Site-wide: 83,698
  • Since beginning of last month:
    • Site-wide: 72,317

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 525 times
  • Download rankings, all-time:
    • Site-wide: 58,932
    • In epidemiology: 2,665
  • Year to date:
    • Site-wide: 135,906
  • Since beginning of last month:
    • Site-wide: 42,522

Improving on a modal-based estimation method: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

genetics more details view paper
  • Downloaded 520 times
  • Download rankings, all-time:
    • Site-wide: 59,689
    • In genetics: 2,629
  • Year to date:
    • Site-wide: 119,584
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    • Site-wide: None

Actionable druggable genome-wide Mendelian randomization identifies repurposingopportunities for COVID-19

epidemiology more details view paper
  • Downloaded 502 times
  • Download rankings, all-time:
    • Site-wide: 62,043
    • In epidemiology: 2,776
  • Year to date:
    • Site-wide: 24,360
  • Since beginning of last month:
    • Site-wide: 87,639

Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

genetics more details view paper
  • Downloaded 468 times
  • Download rankings, all-time:
    • Site-wide: 66,996
    • In genetics: 2,949
  • Year to date:
    • Site-wide: 148,601
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    • Site-wide: None

Bayesian variable selection with a pleiotropic loss function in Mendelian randomization

genetics more details view paper
  • Downloaded 458 times
  • Download rankings, all-time:
    • Site-wide: 68,645
    • In genetics: 3,021
  • Year to date:
    • Site-wide: 95,328
  • Since beginning of last month:
    • Site-wide: 41,640

Leveraging genetic data to elucidate the relationship between Covid-19 and ischemic stroke

cardiovascular medicine more details view paper
  • Downloaded 434 times
  • Download rankings, all-time:
    • Site-wide: 72,625
    • In cardiovascular medicine: 125
  • Year to date:
    • Site-wide: 11,454
  • Since beginning of last month:
    • Site-wide: 99,721

Semiparametric methods for estimation of a non-linear exposure-outcome relationship using instrumental variables with application to Mendelian randomization

genetics more details view paper
  • Downloaded 410 times
  • Download rankings, all-time:
    • Site-wide: 76,721
    • In genetics: 3,342
  • Year to date:
    • Site-wide: 105,110
  • Since beginning of last month:
    • Site-wide: 64,692

Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans

genetics more details view paper
  • Downloaded 409 times
  • Download rankings, all-time:
    • Site-wide: 76,907
    • In genetics: 3,350
  • Year to date:
    • Site-wide: 51,119
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    • Site-wide: None

Urinary biomarkers and cardiovascular outcomes in the UK Biobank: observational and Mendelian randomization analyses

epidemiology more details view paper
  • Downloaded 393 times
  • Download rankings, all-time:
    • Site-wide: 79,760
    • In epidemiology: 3,424
  • Year to date:
    • Site-wide: 130,873
  • Since beginning of last month:
    • Site-wide: 59,207

Body size and composition and site-specific cancers in UK Biobank: a Mendelian randomisation study

genetics more details view paper
  • Downloaded 379 times
  • Download rankings, all-time:
    • Site-wide: 82,512
    • In genetics: 3,593
  • Year to date:
    • Site-wide: 80,465
  • Since beginning of last month:
    • Site-wide: 123,907

Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity

genetics more details view paper
  • Downloaded 377 times
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    • Site-wide: 82,944
    • In genetics: 3,612
  • Year to date:
    • Site-wide: 13,944
  • Since beginning of last month:
    • Site-wide: 4,074

Association of Inflammation with Depression and Anxiety: Evidence for Symptom-Specificity and Potential Causality from UK Biobank and NESDA Cohorts

psychiatry and clinical psychology more details view paper
  • Downloaded 356 times
  • Download rankings, all-time:
    • Site-wide: 87,231
    • In psychiatry and clinical psychology: 331
  • Year to date:
    • Site-wide: 15,230
  • Since beginning of last month:
    • Site-wide: 54,001

Genetically proxied inhibition of interleukin-6 signaling: opposing associations with susceptibility to COVID-19 and pneumonia

genetic and genomic medicine more details view paper
  • Downloaded 322 times
  • Download rankings, all-time:
    • Site-wide: 94,473
    • In genetic and genomic medicine: 434
  • Year to date:
    • Site-wide: 68,407
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    • Site-wide: 44,345

Role of Inflammation in Depression and Anxiety: Tests for Disorder Specificity, Linearity and Potential Causality of Association in the UK Biobank

psychiatry and clinical psychology more details view paper
  • Downloaded 310 times
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    • Site-wide: 97,210
    • In psychiatry and clinical psychology: 392
  • Year to date:
    • Site-wide: 18,476
  • Since beginning of last month:
    • Site-wide: 87,841

Predicting the efficacy of exenatide in Parkinson's disease using genetics - a Mendelian randomization study

neurology more details view paper
  • Downloaded 303 times
  • Download rankings, all-time:
    • Site-wide: 98,858
    • In neurology: 315
  • Year to date:
    • Site-wide: 60,110
  • Since beginning of last month:
    • Site-wide: 38,988

Genome-wide association study of skin and soft tissue infection susceptibility

genetic and genomic medicine more details view paper
  • Downloaded 302 times
  • Download rankings, all-time:
    • Site-wide: 99,213
    • In genetic and genomic medicine: 469
  • Year to date:
    • Site-wide: 43,447
  • Since beginning of last month:
    • Site-wide: 56,694

Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease

cardiovascular medicine more details view paper
  • Downloaded 293 times
  • Download rankings, all-time:
    • Site-wide: 101,301
    • In cardiovascular medicine: 206
  • Year to date:
    • Site-wide: 20,030
  • Since beginning of last month:
    • Site-wide: 16,595

Estimating the Population Benefits of Blood Pressure Lowering: A Wide-Angled Mendelian Randomization Study in UK Biobank

epidemiology more details view paper
  • Downloaded 246 times
  • Download rankings, all-time:
    • Site-wide: 112,602
    • In epidemiology: 4,731
  • Year to date:
    • Site-wide: 25,272
  • Since beginning of last month:
    • Site-wide: 21,366

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

epidemiology more details view paper
  • Downloaded 238 times
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    • Site-wide: 114,762
    • In epidemiology: 4,822
  • Year to date:
    • Site-wide: 129,092
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    • Site-wide: 51,449

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

epidemiology more details view paper
  • Downloaded 215 times
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    • Site-wide: 120,470
    • In epidemiology: 5,059
  • Year to date:
    • Site-wide: 139,666
  • Since beginning of last month:
    • Site-wide: 51,448

Cross-fitted instrument: a blueprint for one-sample Mendelian Randomization

bioinformatics more details view paper
  • Downloaded 169 times
  • Download rankings, all-time:
    • Site-wide: 131,557
    • In bioinformatics: 10,400
  • Year to date:
    • Site-wide: 40,032
  • Since beginning of last month:
    • Site-wide: 93,287

Design and quality control of large-scale two-sample Mendelian randomisation studies

epidemiology more details view paper
  • Downloaded 94 times
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    • Site-wide: 147,069
    • In epidemiology: 6,072
  • Year to date:
    • Site-wide: 72,325
  • Since beginning of last month:
    • Site-wide: 3,840

Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

epidemiology more details view paper
  • Downloaded 72 times
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    • Site-wide: 150,132
    • In epidemiology: 6,196
  • Year to date:
    • Site-wide: 90,122
  • Since beginning of last month:
    • Site-wide: 132,956

Thyroid function and the risk of Alzheimer's disease: A Mendelian Randomisation study

endocrinology more details view paper
  • Downloaded 47 times
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    • Site-wide: 152,446
    • In endocrinology: 220
  • Year to date:
    • Site-wide: 118,933
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    • Site-wide: 133,066

Avoiding bias in Mendelian randomization when stratifying on a collider

epidemiology more details view paper
  • Downloaded 28 times
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    • Site-wide: 153,320
    • In epidemiology: 6,318
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