Author: Hannele Ruohola-Baker

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Preprints

Robust de novo design of protein binding proteins from target structural information alone

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Designed proteins assemble antibodies into modular nanocages

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  • In biochemistry: 216
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Cardiac differentiation at single cell resolution reveals a requirement of hypertrophic signaling for HOPX transcription

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  • In developmental biology: 134
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Multivalent designed proteins protect against SARS-CoV-2 variants of concern

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Isolator: accurate and stable analysis of isoform-level expression in RNA-Seq experiments

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  • In bioinformatics: 1,293
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Epigenomic and 3D genome architecture in naïve and primed human embryonic stem cell states

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  • In developmental biology: 262
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Design of Biologically Active Binary Protein 2D Materials

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Engineered developmental niche enables predictive phenotypic screening in human dystrophic cardiomyopathy

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  • In bioengineering: 672
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F-domain valency determines outcome of signaling through the angiopoietin pathway

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  • In biochemistry: 1,823
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Computer Designed PRC2 Inhibitor, EBdCas9, Reveals Functional TATA boxes in Distal Promoter Regions

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  • In molecular biology: 2,185
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Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma

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  • In cancer biology: 2,400
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Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

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  • In biochemistry: 3,265
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