Author: Aiden Corvin

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

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Brain charts for the human lifespan

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  • In neuroscience: 148
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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 2,678
  • In genetics: 71
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  • Site-wide: 29,974
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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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  • In genetics: 172
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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 7,570
  • In genetics: 351
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 12,514
  • In genetics: 470
• Year to date:
  • Site-wide: 153,817
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 17,225
  • In genomics: 1,529
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Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

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  • Site-wide: 21,306
  • In genetic and genomic medicine: 147
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Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

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  • In genetics: 1,468
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Planar cell polarity pathway and development of the human visual cortex

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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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  • In genetics: 1,450
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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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  • Site-wide: 40,804
  • In genetic and genomic medicine: 211
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  • Site-wide: 92,676
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Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

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  • In genomics: 3,224
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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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  • In genetics: 1,775
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

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Functional MRI connectivity accurately distinguishes cases with psychotic disorders from healthy controls, based on cortical features associated with neurodevelopment

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  • Site-wide: 52,033
  • In psychiatry and clinical psychology: 193
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Proof of concept: Molecular prediction of schizophrenia risk

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  • In genomics: 3,806
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Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

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  • Site-wide: 56,406
  • In genomics: 4,024
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Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia related genes

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  • Site-wide: 67,212
  • In neuroscience: 9,116
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  • Site-wide: 95,236

Characterization of Age and Polarity at Onset in Bipolar Disorder

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  • Site-wide: 97,439
  • In psychiatry and clinical psychology: 478
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  • Site-wide: 47,304
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Methyl-CpG2-binding protein 2 mediates overlapping mechanisms across brain disorders.

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  • Site-wide: 152,897
  • In neuroscience: 21,279
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