Author: Brien P Riley

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 9,403
  • In genetics: 427
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia risk.

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  • Site-wide: 21,244
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Polygenic prediction of the phenome, across ancestry, in emerging adulthood

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Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

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  • Site-wide: 30,183
  • In genetics: 1,426
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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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  • In genetics: 1,578
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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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Proof of concept: Molecular prediction of schizophrenia risk

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TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

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  • In bioinformatics: 5,329
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Cross-species alcohol dependence-associated gene networks: Co-analysis of mouse brain gene expression and human genome-wide association data

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FIQT: a simple, powerful method to accurately estimate effect sizes in genome scans

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Increasing the resolution and precision of psychiatric GWAS by re-imputing summary statistics using a large, diverse reference panel

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  • Site-wide: 83,340
  • In bioinformatics: 7,539
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Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence

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