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Author: Bogdan Pasaniuc

Rankings

  • All-time downloads: 63,824 (rank: 2,146 )
  • Categories:
    • bioinformatics: 7,006 (rank: 1,455 )
    • cancer biology: 446 (rank: 18,658 (tie) )
    • epidemiology: 1,389 (rank: 7,083 (tie) )
    • genetic and genomic medicine: 821 (rank: 2,520 (tie) )
    • genetics: 37,421 (rank: 144 )
    • genomics: 11,823 (rank: 1,501 )
    • infectious diseases: 2,213 (rank: 13,233 (tie) )
    • neuroscience: 2,705 (rank: 7,839 (tie) )

Downloads per author, site-wide

Preprints

Transcriptome-wide association studies: opportunities and challenges

genetics more details view paper
  • Downloaded 4,857 times
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    • Site-wide: 2,092
    • In genetics: 74
  • Year to date:
    • Site-wide: 11,746
  • Since beginning of last month:
    • Site-wide: 11,146

Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
  • Downloaded 4,463 times
  • Download rankings, all-time:
    • Site-wide: 2,364
    • In genetics: 88
  • Year to date:
    • Site-wide: 87,431
  • Since beginning of last month:
    • Site-wide: 79,861

Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
  • Downloaded 3,080 times
  • Download rankings, all-time:
    • Site-wide: 4,022
    • In genetics: 169
  • Year to date:
    • Site-wide: 86,126
  • Since beginning of last month:
    • Site-wide: 81,728

Integrative approaches for large-scale transcriptome-wide association studies

genetics more details view paper
  • Downloaded 2,907 times
  • Download rankings, all-time:
    • Site-wide: 4,359
    • In genetics: 192
  • Year to date:
    • Site-wide: 40,799
  • Since beginning of last month:
    • Site-wide: 43,201

Dissecting the genetics of complex traits using summary association statistics

genetics more details view paper
  • Downloaded 2,877 times
  • Download rankings, all-time:
    • Site-wide: 4,428
    • In genetics: 194
  • Year to date:
    • Site-wide: 27,564
  • Since beginning of last month:
    • Site-wide: 33,134

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,570 times
  • Download rankings, all-time:
    • Site-wide: 5,203
    • In genomics: 583
  • Year to date:
    • Site-wide: 118,093
  • Since beginning of last month:
    • Site-wide: 110,836

A Bayesian Framework for Multiple Trait Colocalization from Summary Association Statistics

genomics more details view paper
  • Downloaded 2,456 times
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    • Site-wide: 5,594
    • In genomics: 634
  • Year to date:
    • Site-wide: 53,168
  • Since beginning of last month:
    • Site-wide: 68,878

Local genetic correlation gives insights into the shared genetic architecture of complex traits

genetics more details view paper
  • Downloaded 2,272 times
  • Download rankings, all-time:
    • Site-wide: 6,268
    • In genetics: 295
  • Year to date:
    • Site-wide: 80,151
  • Since beginning of last month:
    • Site-wide: 86,726

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

genomics more details view paper
  • Downloaded 2,166 times
  • Download rankings, all-time:
    • Site-wide: 6,705
    • In genomics: 742
  • Year to date:
    • Site-wide: 22,302
  • Since beginning of last month:
    • Site-wide: 27,614

Genetic control of gene expression and splicing in the developing human brain

neuroscience more details view paper
  • Downloaded 2,119 times
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    • Site-wide: 6,941
    • In neuroscience: 686
  • Year to date:
    • Site-wide: 31,374
  • Since beginning of last month:
    • Site-wide: 39,224

Contrasting the genetic architecture of 30 complex traits from summary association data

bioinformatics more details view paper
  • Downloaded 1,979 times
  • Download rankings, all-time:
    • Site-wide: 7,670
    • In bioinformatics: 919
  • Year to date:
    • Site-wide: 79,475
  • Since beginning of last month:
    • Site-wide: 92,603

Probabilistic fine-mapping of transcriptome-wide association studies

genetics more details view paper
  • Downloaded 1,895 times
  • Download rankings, all-time:
    • Site-wide: 8,180
    • In genetics: 372
  • Year to date:
    • Site-wide: 63,648
  • Since beginning of last month:
    • Site-wide: 44,970

Integrating gene expression with summary association statistics to identify susceptibility genes for 30 complex traits

genetics more details view paper
  • Downloaded 1,871 times
  • Download rankings, all-time:
    • Site-wide: 8,344
    • In genetics: 388
  • Year to date:
    • Site-wide: 112,972
  • Since beginning of last month:
    • Site-wide: 98,795

Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System

infectious diseases more details view paper
  • Downloaded 1,845 times
  • Download rankings, all-time:
    • Site-wide: 8,525
    • In infectious diseases: 1,122
  • Year to date:
    • Site-wide: 6,394
  • Since beginning of last month:
    • Site-wide: 7,921

Widespread allelic heterogeneity in complex traits

genetics more details view paper
  • Downloaded 1,836 times
  • Download rankings, all-time:
    • Site-wide: 8,580
    • In genetics: 401
  • Year to date:
    • Site-wide: 93,105
  • Since beginning of last month:
    • Site-wide: 96,116

Colocalization of GWAS and eQTL Signals Detects Target Genes

genetics more details view paper
  • Downloaded 1,618 times
  • Download rankings, all-time:
    • Site-wide: 10,352
    • In genetics: 497
  • Year to date:
    • Site-wide: 92,558
  • Since beginning of last month:
    • Site-wide: 74,276

Efficient variance components analysis across millions of genomes

bioinformatics more details view paper
  • Downloaded 1,402 times
  • Download rankings, all-time:
    • Site-wide: 12,801
    • In bioinformatics: 1,545
  • Year to date:
    • Site-wide: 40,572
  • Since beginning of last month:
    • Site-wide: 52,809

Transcriptome-wide association studies accounting for colocalization using Egger regression

epidemiology more details view paper
  • Downloaded 1,389 times
  • Download rankings, all-time:
    • Site-wide: 12,991
    • In epidemiology: 878
  • Year to date:
    • Site-wide: 104,187
  • Since beginning of last month:
    • Site-wide: 112,931

Leveraging polygenic functional enrichment to improve GWAS power

genetics more details view paper
  • Downloaded 1,343 times
  • Download rankings, all-time:
    • Site-wide: 13,659
    • In genetics: 661
  • Year to date:
    • Site-wide: 112,325
  • Since beginning of last month:
    • Site-wide: 113,487

Optimal design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

bioinformatics more details view paper
  • Downloaded 1,215 times
  • Download rankings, all-time:
    • Site-wide: 15,925
    • In bioinformatics: 1,914
  • Year to date:
    • Site-wide: 47,749
  • Since beginning of last month:
    • Site-wide: 40,965

Improved methods for multi-trait fine mapping of pleiotropic risk loci

genetics more details view paper
  • Downloaded 1,198 times
  • Download rankings, all-time:
    • Site-wide: 16,224
    • In genetics: 794
  • Year to date:
    • Site-wide: 93,307
  • Since beginning of last month:
    • Site-wide: 68,589

Subtle stratification confounds estimates of heritability from rare variants

genetics more details view paper
  • Downloaded 1,160 times
  • Download rankings, all-time:
    • Site-wide: 17,061
    • In genetics: 829
  • Year to date:
    • Site-wide: 77,515
  • Since beginning of last month:
    • Site-wide: 74,325

Spatial localization of recent ancestors for admixed individuals

genetics more details view paper
  • Downloaded 1,136 times
  • Download rankings, all-time:
    • Site-wide: 17,574
    • In genetics: 852
  • Year to date:
    • Site-wide: 108,211
  • Since beginning of last month:
    • Site-wide: 116,862

Large uncertainty in individual PRS estimation impacts PRS-based risk stratification

genomics more details view paper
  • Downloaded 1,072 times
  • Download rankings, all-time:
    • Site-wide: 19,140
    • In genomics: 1,933
  • Year to date:
    • Site-wide: 4,157
  • Since beginning of last month:
    • Site-wide: 3,916

Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data

genomics more details view paper
  • Downloaded 1,021 times
  • Download rankings, all-time:
    • Site-wide: 20,566
    • In genomics: 2,055
  • Year to date:
    • Site-wide: 98,328
  • Since beginning of last month:
    • Site-wide: 99,732

Multi-Tissue Transcriptome-Wide Association Studies Identify 21 Novel Candidate Susceptibility Genes for High Grade Serous Epithelial Ovarian Cancer

genomics more details view paper
  • Downloaded 927 times
  • Download rankings, all-time:
    • Site-wide: 23,626
    • In genomics: 2,282
  • Year to date:
    • Site-wide: 101,668
  • Since beginning of last month:
    • Site-wide: 113,208

Fast estimation of genetic correlation for Biobank-scale data

bioinformatics more details view paper
  • Downloaded 887 times
  • Download rankings, all-time:
    • Site-wide: 25,242
    • In bioinformatics: 2,952
  • Year to date:
    • Site-wide: 32,582
  • Since beginning of last month:
    • Site-wide: 28,603

Leveraging eQTLs to identify individual-level tissue of interest for a complex trait

genetics more details view paper
  • Downloaded 859 times
  • Download rankings, all-time:
    • Site-wide: 26,319
    • In genetics: 1,269
  • Year to date:
    • Site-wide: 63,758
  • Since beginning of last month:
    • Site-wide: 116,863

Integrative analyses identify susceptibility genes underlying COVID-19 hospitalization

genetic and genomic medicine more details view paper
  • Downloaded 821 times
  • Download rankings, all-time:
    • Site-wide: 28,039
    • In genetic and genomic medicine: 90
  • Year to date:
    • Site-wide: 6,130
  • Since beginning of last month:
    • Site-wide: 10,847

A method to map and interpret pleiotropic loci using summary statistics of multiple traits

bioinformatics more details view paper
  • Downloaded 756 times
  • Download rankings, all-time:
    • Site-wide: 31,515
    • In bioinformatics: 3,540
  • Year to date:
    • Site-wide: 21,455
  • Since beginning of last month:
    • Site-wide: 30,290

Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion

genomics more details view paper
  • Downloaded 656 times
  • Download rankings, all-time:
    • Site-wide: 38,145
    • In genomics: 3,215
  • Year to date:
    • Site-wide: 37,515
  • Since beginning of last month:
    • Site-wide: 34,154

Integrative analysis of Dupuytren's disease identifies novel risk locus and reveals a shared genetic etiology with BMI

genetics more details view paper
  • Downloaded 651 times
  • Download rankings, all-time:
    • Site-wide: 38,531
    • In genetics: 1,832
  • Year to date:
    • Site-wide: 123,699
  • Since beginning of last month:
    • Site-wide: 114,209

A scalable method for estimating the regional polygenicity of complex traits

genetics more details view paper
  • Downloaded 590 times
  • Download rankings, all-time:
    • Site-wide: 43,606
    • In genetics: 2,042
  • Year to date:
    • Site-wide: 78,859
  • Since beginning of last month:
    • Site-wide: 66,247

Broad transcriptomic dysregulation across the cerebral cortex in ASD

neuroscience more details view paper
  • Downloaded 586 times
  • Download rankings, all-time:
    • Site-wide: 44,011
    • In neuroscience: 6,324
  • Year to date:
    • Site-wide: 6,383
  • Since beginning of last month:
    • Site-wide: 8,430

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

genetics more details view paper
  • Downloaded 559 times
  • Download rankings, all-time:
    • Site-wide: 46,639
    • In genetics: 2,190
  • Year to date:
    • Site-wide: 106,575
  • Since beginning of last month:
    • Site-wide: 112,511

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders

genetics more details view paper
  • Downloaded 540 times
  • Download rankings, all-time:
    • Site-wide: 48,665
    • In genetics: 2,277
  • Year to date:
    • Site-wide: 133,922
  • Since beginning of last month:
    • Site-wide: 132,653

Haplotype-based eQTL mapping finds evidence for complex gene regulatory regions poorly tagged by marginal SNPs

genetics more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 49,436
    • In genetics: 2,300
  • Year to date:
    • Site-wide: 86,596
  • Since beginning of last month:
    • Site-wide: 118,162

Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 49,782
    • In genomics: 3,900
  • Year to date:
    • Site-wide: 121,232
  • Since beginning of last month:
    • Site-wide: 123,195

A unifying framework for joint trait analysis under a non-infinitesimal model

bioinformatics more details view paper
  • Downloaded 503 times
  • Download rankings, all-time:
    • Site-wide: 52,966
    • In bioinformatics: 5,393
  • Year to date:
    • Site-wide: 135,521
  • Since beginning of last month:
    • Site-wide: 135,367

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

cancer biology more details view paper
  • Downloaded 446 times
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    • Site-wide: 60,296
    • In cancer biology: 1,722
  • Year to date:
    • Site-wide: 9,736
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    • Site-wide: 10,180

H3k27ac-HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility

genomics more details view paper
  • Downloaded 425 times
  • Download rankings, all-time:
    • Site-wide: 63,383
    • In genomics: 4,565
  • Year to date:
    • Site-wide: 24,399
  • Since beginning of last month:
    • Site-wide: 18,478

Leveraging expression from multiple tissues using sparse canonical correlation analysis (sCCA) and aggregate tests improves the power of transcriptome-wide association studies (TWAS)

genetics more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 72,705
    • In genetics: 3,306
  • Year to date:
    • Site-wide: 18,764
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    • Site-wide: 12,017

Credible learning of hydroxychloroquine and dexamethasone effects on COVID-19 mortality outside of randomized trials

infectious diseases more details view paper
  • Downloaded 368 times
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    • Site-wide: 72,677
    • In infectious diseases: 3,212
  • Year to date:
    • Site-wide: 14,868
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    • Site-wide: 24,238

Quantifying the contribution of dominance effects to complex trait variation in biobank-scale data

genetics more details view paper
  • Downloaded 354 times
  • Download rankings, all-time:
    • Site-wide: 75,227
    • In genetics: 3,423
  • Year to date:
    • Site-wide: 41,656
  • Since beginning of last month:
    • Site-wide: 36,358

RAISS: Robust and Accurate imputation from Summary Statistics

bioinformatics more details view paper
  • Downloaded 264 times
  • Download rankings, all-time:
    • Site-wide: 93,776
    • In bioinformatics: 8,210
  • Year to date:
    • Site-wide: 134,432
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    • Site-wide: 123,678

Gene expression imputation provides insight into the genetic architecture of frontotemporal dementia

genetics more details view paper
  • Downloaded 240 times
  • Download rankings, all-time:
    • Site-wide: 98,900
    • In genetics: 4,394
  • Year to date:
    • Site-wide: 63,008
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    • Site-wide: 56,499

A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes

genetics more details view paper
  • Downloaded 214 times
  • Download rankings, all-time:
    • Site-wide: 104,969
    • In genetics: 4,625
  • Year to date:
    • Site-wide: 45,760
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    • Site-wide: 54,938

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