Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 65,351 bioRxiv papers from 289,483 authors.

Author: Alexander Gusev

  • Most recently observed institution: Dana-Farber Cancer Institute

Rankings

  • All-time downloads: 64,121 (rank: 190 out of 289,483)
  • Categories:
    • cancer biology: 529 (rank: 6,304 (tie) out of 18,052)
    • epidemiology: 1,209 (rank: 762 (tie) out of 9,549)
    • evolutionary biology: 1,291 (rank: 2,313 (tie) out of 15,773)
    • genetics: 41,531 (rank: 81 out of 28,760)
    • genomics: 19,561 (rank: 339 out of 32,918)

Downloads per author, site-wide

Preprints

An Atlas of Genetic Correlations across Human Diseases and Traits

genomics more details view paper
  • Downloaded 12,924 times
  • Download rankings, all-time:
    • Site-wide: 69 out of 65,351
    • In genomics: 20 out of 4,459
  • Year to date:
    • Site-wide: 2,937 out of 65,351
  • Since beginning of last month:
    • Site-wide: 8,167 out of 65,351

Partitioning heritability by functional category using GWAS summary statistics

genetics more details view paper
  • Downloaded 6,762 times
  • Download rankings, all-time:
    • Site-wide: 250 out of 65,351
    • In genetics: 27 out of 3,696
  • Year to date:
    • Site-wide: 2,495 out of 65,351
  • Since beginning of last month:
    • Site-wide: 11,923 out of 65,351

Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
  • Downloaded 4,265 times
  • Download rankings, all-time:
    • Site-wide: 587 out of 65,351
    • In genetics: 60 out of 3,696
  • Year to date:
    • Site-wide: 27,481 out of 65,351
  • Since beginning of last month:
    • Site-wide: 31,421 out of 65,351

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

genetics more details view paper
  • Downloaded 3,827 times
  • Download rankings, all-time:
    • Site-wide: 725 out of 65,351
    • In genetics: 68 out of 3,696
  • Year to date:
    • Site-wide: 10,390 out of 65,351
  • Since beginning of last month:
    • Site-wide: 16,138 out of 65,351

Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

genetics more details view paper
  • Downloaded 2,957 times
  • Download rankings, all-time:
    • Site-wide: 1,176 out of 65,351
    • In genetics: 110 out of 3,696
  • Year to date:
    • Site-wide: 36,916 out of 65,351
  • Since beginning of last month:
    • Site-wide: 34,567 out of 65,351

Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
  • Downloaded 2,922 times
  • Download rankings, all-time:
    • Site-wide: 1,209 out of 65,351
    • In genetics: 115 out of 3,696
  • Year to date:
    • Site-wide: 36,640 out of 65,351
  • Since beginning of last month:
    • Site-wide: 32,101 out of 65,351

Tumor mutational landscape is a record of the pre-malignant state

genomics more details view paper
  • Downloaded 2,746 times
  • Download rankings, all-time:
    • Site-wide: 1,335 out of 65,351
    • In genomics: 306 out of 4,459
  • Year to date:
    • Site-wide: 252 out of 65,351
  • Since beginning of last month:
    • Site-wide: 3,444 out of 65,351

Integrative approaches for large-scale transcriptome-wide association studies

genetics more details view paper
  • Downloaded 2,636 times
  • Download rankings, all-time:
    • Site-wide: 1,424 out of 65,351
    • In genetics: 136 out of 3,696
  • Year to date:
    • Site-wide: 20,917 out of 65,351
  • Since beginning of last month:
    • Site-wide: 21,165 out of 65,351

Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection

genetics more details view paper
  • Downloaded 2,550 times
  • Download rankings, all-time:
    • Site-wide: 1,513 out of 65,351
    • In genetics: 146 out of 3,696
  • Year to date:
    • Site-wide: 23,617 out of 65,351
  • Since beginning of last month:
    • Site-wide: 27,159 out of 65,351

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,417 times
  • Download rankings, all-time:
    • Site-wide: 1,678 out of 65,351
    • In genomics: 373 out of 4,459
  • Year to date:
    • Site-wide: 20,579 out of 65,351
  • Since beginning of last month:
    • Site-wide: 20,645 out of 65,351

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

genetics more details view paper
  • Downloaded 2,312 times
  • Download rankings, all-time:
    • Site-wide: 1,823 out of 65,351
    • In genetics: 171 out of 3,696
  • Year to date:
    • Site-wide: 16,068 out of 65,351
  • Since beginning of last month:
    • Site-wide: 12,585 out of 65,351

Estimating the proportion of disease heritability mediated by gene expression levels

genetics more details view paper
  • Downloaded 2,024 times
  • Download rankings, all-time:
    • Site-wide: 2,304 out of 65,351
    • In genetics: 216 out of 3,696
  • Year to date:
    • Site-wide: 15,603 out of 65,351
  • Since beginning of last month:
    • Site-wide: 23,332 out of 65,351

Integrating gene expression with summary association statistics to identify susceptibility genes for 30 complex traits

genetics more details view paper
  • Downloaded 1,739 times
  • Download rankings, all-time:
    • Site-wide: 2,987 out of 65,351
    • In genetics: 263 out of 3,696
  • Year to date:
    • Site-wide: 27,784 out of 65,351
  • Since beginning of last month:
    • Site-wide: 36,287 out of 65,351

Probabilistic fine-mapping of transcriptome-wide association studies

genetics more details view paper
  • Downloaded 1,527 times
  • Download rankings, all-time:
    • Site-wide: 3,695 out of 65,351
    • In genetics: 321 out of 3,696
  • Year to date:
    • Site-wide: 4,161 out of 65,351
  • Since beginning of last month:
    • Site-wide: 9,237 out of 65,351

Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits

genetics more details view paper
  • Downloaded 1,526 times
  • Download rankings, all-time:
    • Site-wide: 3,696 out of 65,351
    • In genetics: 322 out of 3,696
  • Year to date:
    • Site-wide: 23,745 out of 65,351
  • Since beginning of last month:
    • Site-wide: 19,753 out of 65,351

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
  • Downloaded 1,335 times
  • Download rankings, all-time:
    • Site-wide: 4,651 out of 65,351
    • In genetics: 384 out of 3,696
  • Year to date:
    • Site-wide: 55,198 out of 65,351
  • Since beginning of last month:
    • Site-wide: 43,585 out of 65,351

An evolutionary compass for detecting signals of polygenic selection and mutational bias

evolutionary biology more details view paper
  • Downloaded 1,291 times
  • Download rankings, all-time:
    • Site-wide: 4,898 out of 65,351
    • In evolutionary biology: 261 out of 4,362
  • Year to date:
    • Site-wide: 25,597 out of 65,351
  • Since beginning of last month:
    • Site-wide: 26,586 out of 65,351

Transcriptome-wide association studies accounting for colocalization using Egger regression

epidemiology more details view paper
  • Downloaded 1,209 times
  • Download rankings, all-time:
    • Site-wide: 5,464 out of 65,351
    • In epidemiology: 52 out of 1,556
  • Year to date:
    • Site-wide: 32,761 out of 65,351
  • Since beginning of last month:
    • Site-wide: 24,169 out of 65,351

Subtle stratification confounds estimates of heritability from rare variants

genetics more details view paper
  • Downloaded 962 times
  • Download rankings, all-time:
    • Site-wide: 7,944 out of 65,351
    • In genetics: 611 out of 3,696
  • Year to date:
    • Site-wide: 38,275 out of 65,351
  • Since beginning of last month:
    • Site-wide: 39,291 out of 65,351

Correcting subtle stratification in summary association statistics

genetics more details view paper
  • Downloaded 789 times
  • Download rankings, all-time:
    • Site-wide: 10,826 out of 65,351
    • In genetics: 782 out of 3,696
  • Year to date:
    • Site-wide: 30,982 out of 65,351
  • Since beginning of last month:
    • Site-wide: 21,323 out of 65,351

Functional partitioning of local and distal gene expression regulation in multiple human tissues

genomics more details view paper
  • Downloaded 773 times
  • Download rankings, all-time:
    • Site-wide: 11,151 out of 65,351
    • In genomics: 1,603 out of 4,459
  • Year to date:
    • Site-wide: 60,243 out of 65,351
  • Since beginning of last month:
    • Site-wide: 62,777 out of 65,351

Multi-Tissue Transcriptome-Wide Association Studies Identify 21 Novel Candidate Susceptibility Genes for High Grade Serous Epithelial Ovarian Cancer

genomics more details view paper
  • Downloaded 701 times
  • Download rankings, all-time:
    • Site-wide: 12,889 out of 65,351
    • In genomics: 1,771 out of 4,459
  • Year to date:
    • Site-wide: 13,701 out of 65,351
  • Since beginning of last month:
    • Site-wide: 22,625 out of 65,351

Leveraging distant relatedness to quantify human mutation and gene conversion rates

genetics more details view paper
  • Downloaded 666 times
  • Download rankings, all-time:
    • Site-wide: 13,833 out of 65,351
    • In genetics: 972 out of 3,696
  • Year to date:
    • Site-wide: 59,395 out of 65,351
  • Since beginning of last month:
    • Site-wide: 61,178 out of 65,351

Germline features associated with immune infiltration in solid tumors

genetics more details view paper
  • Downloaded 637 times
  • Download rankings, all-time:
    • Site-wide: 14,679 out of 65,351
    • In genetics: 1,016 out of 3,696
  • Year to date:
    • Site-wide: 3,846 out of 65,351
  • Since beginning of last month:
    • Site-wide: 18,522 out of 65,351

Quantifying genetic effects on disease mediated by assayed gene expression levels

genetics more details view paper
  • Downloaded 608 times
  • Download rankings, all-time:
    • Site-wide: 15,701 out of 65,351
    • In genetics: 1,079 out of 3,696
  • Year to date:
    • Site-wide: 4,141 out of 65,351
  • Since beginning of last month:
    • Site-wide: 2,285 out of 65,351

Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer

cancer biology more details view paper
  • Downloaded 529 times
  • Download rankings, all-time:
    • Site-wide: 18,932 out of 65,351
    • In cancer biology: 566 out of 2,178
  • Year to date:
    • Site-wide: 5,269 out of 65,351
  • Since beginning of last month:
    • Site-wide: 9,850 out of 65,351

Mixed Model Association with Family-Biased Case-Control Ascertainment

genetics more details view paper
  • Downloaded 419 times
  • Download rankings, all-time:
    • Site-wide: 24,978 out of 65,351
    • In genetics: 1,641 out of 3,696
  • Year to date:
    • Site-wide: 56,372 out of 65,351
  • Since beginning of last month:
    • Site-wide: 59,338 out of 65,351

Annotations capturing cell-type-specific TF binding explain a large fraction of disease heritability

genetics more details view paper
  • Downloaded 413 times
  • Download rankings, all-time:
    • Site-wide: 25,362 out of 65,351
    • In genetics: 1,669 out of 3,696
  • Year to date:
    • Site-wide: 23,793 out of 65,351
  • Since beginning of last month:
    • Site-wide: 28,848 out of 65,351

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

genetics more details view paper
  • Downloaded 402 times
  • Download rankings, all-time:
    • Site-wide: 26,168 out of 65,351
    • In genetics: 1,714 out of 3,696
  • Year to date:
    • Site-wide: 44,057 out of 65,351
  • Since beginning of last month:
    • Site-wide: 45,556 out of 65,351

Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell Carcinoma

genetics more details view paper
  • Downloaded 253 times
  • Download rankings, all-time:
    • Site-wide: 39,881 out of 65,351
    • In genetics: 2,437 out of 3,696
  • Year to date:
    • Site-wide: 16,927 out of 65,351
  • Since beginning of last month:
    • Site-wide: 11,987 out of 65,351

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News