Author: Lars Lind

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Preprints

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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  • Site-wide: 4,775
  • In genomics: 469
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  • Site-wide: 109,066
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  • Site-wide: 143,462

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 4,829
  • In genetics: 181
• Year to date:
  • Site-wide: 43,586
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  • Site-wide: 63,059

Large-scale non-targeted metabolomic profiling in three human population-based studies

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  • Site-wide: 5,080
  • In bioinformatics: 476
• Year to date:
  • Site-wide: 50,918
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Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

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  • Site-wide: 6,401
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• Year to date:
  • Site-wide: 10,220
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  • Site-wide: 14,522

Identification of rare-disease genes in diverse undiagnosed cases using whole blood transcriptome sequencing and large control cohorts

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  • Site-wide: 7,240
  • In genomics: 744
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  • Site-wide: 80,719

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 10,728
  • In genetics: 454
• Year to date:
  • Site-wide: 131,251
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  • Site-wide: 157,637

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

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  • Site-wide: 11,867
  • In genetic and genomic medicine: 54
• Year to date:
  • Site-wide: 5,810
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  • Site-wide: 5,639

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 11,952
  • In genetics: 509
• Year to date:
  • Site-wide: 79,468
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  • Site-wide: 132,662

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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  • Site-wide: 12,955
  • In genomics: 1,292
• Year to date:
  • Site-wide: 89,744
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  • Site-wide: 89,432

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 14,538
  • In genetics: 636
• Year to date:
  • Site-wide: 105,860
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  • Site-wide: 88,917

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 21,873
  • In genetics: 956
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  • Site-wide: 13,306
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  • Site-wide: 79,631

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 25,547
  • In genetics: 1,122
• Year to date:
  • Site-wide: 30,163
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  • Site-wide: 64,058

Genetic dysregulation of gene expression and splicing during a ten-year period of human aging

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  • Site-wide: 33,945
  • In genomics: 2,852
• Year to date:
  • Site-wide: 133,803
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  • Site-wide: 122,219

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 34,110
  • In genetics: 1,491
• Year to date:
  • Site-wide: 114,202
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  • Site-wide: 141,956

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

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  • Site-wide: 35,122
  • In infectious diseases: 2,781
• Year to date:
  • Site-wide: 6,756
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  • Site-wide: 7,568

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 39,584
  • In genomics: 3,191
• Year to date:
  • Site-wide: 140,534
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  • Site-wide: 145,674

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

• Downloaded 758 times
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  • Site-wide: 42,772
  • In genetics: 1,849
• Year to date:
  • Site-wide: 150,592
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  • Site-wide: 132,897

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

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  • Site-wide: 47,149
  • In genetics: 2,021
• Year to date:
  • Site-wide: 151,861
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  • Site-wide: 160,696

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • Site-wide: 51,048
  • In genetics: 2,174
• Year to date:
  • Site-wide: 127,995
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  • Site-wide: 141,594

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 57,112
  • In genetics: 2,417
• Year to date:
  • Site-wide: 138,153
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  • Site-wide: 157,587

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 529 times
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  • Site-wide: 68,633
  • In genetics: 2,917
• Year to date:
  • Site-wide: 144,013
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  • Site-wide: 94,246

Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and disease.

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  • Site-wide: 114,315
  • In genetic and genomic medicine: 641
• Year to date:
  • Site-wide: 33,233
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  • Site-wide: 50,467

Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

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  • Site-wide: 123,434
  • In genetic and genomic medicine: 713
• Year to date:
  • Site-wide: 38,908
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  • Site-wide: 40,921

Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization

• Downloaded 96 times
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  • Site-wide: 160,897
  • In genetic and genomic medicine: 1,034
• Year to date:
  • Site-wide: 118,823
• Since beginning of last month:
  • Site-wide: 18,756