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Author: William Greenleaf

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    • bioinformatics: 6,618 (rank: 1,223 out of 34,272)
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    • developmental biology: 2,718 (rank: 550 (tie) out of 15,768)
    • genetics: 632 (rank: 18,702 (tie) out of 36,792)
    • genomics: 54,681 (rank: 116 out of 42,763)
    • molecular biology: 4,082 (rank: 495 out of 21,566)
    • synthetic biology: 572 (rank: 2,418 (tie) out of 4,220)

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Preprints

Size-independent mRNA synthesis and chromatin-based partitioning mechanisms generate and maintain constant amounts of protein per cell

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Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

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Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation

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Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks

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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

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Single-cell epigenomic identification of inherited risk loci in Alzheimer's and Parkinson's disease

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Landscape of stimulation-responsive chromatin across diverse human immune cells

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Unsupervised clustering and epigenetic classification of single cells

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ArchR: An integrative and scalable software package for single-cell chromatin accessibility analysis

genomics more details view paper
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High-throughput chromatin accessibility profiling at single-cell resolution

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Large-scale, quantitative protein assays on a high-throughput DNA sequencing chip

molecular biology more details view paper
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Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans

genomics more details view paper
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chromVAR: Inferring transcription factor variation from single-cell epigenomic data

bioinformatics more details view paper
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HiChIP: Efficient and sensitive analysis of protein-directed genome architecture

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Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

genomics more details view paper
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Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

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Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

genomics more details view paper
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High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity

biochemistry more details view paper
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High-resolution mapping of cancer cell networks using co-functional interactions

genomics more details view paper
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High-Resolution Dissection of Conducive Reprogramming Trajectory to Ground State Pluripotency

developmental biology more details view paper
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Prospects for recurrent neural network models to learn RNA biophysics from high-throughput data

biophysics more details view paper
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Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

developmental biology more details view paper
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A quantitative and predictive model for RNA binding by human Pumilio proteins

biochemistry more details view paper
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RNA tertiary structure energetics predicted by an ensemble model of the RNA double helix

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Satb1 integrates DNA sequence, shape, motif density and torsional stress to differentially bind targets in nucleosome-dense regions.

molecular biology more details view paper
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Quantitative high-throughput tests of ubiquitous RNA secondary structure prediction algorithms via RNA/protein binding

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Cell cycle dynamics of human pluripotent stem cells primed for differentiation

genetics more details view paper
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Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular sensors

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Nonparametric analysis of contributions to variance in genomics and epigenomics data

bioinformatics more details view paper
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Transcription-dependent domain-scale 3D genome organization in dinoflagellates

genomics more details view paper
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INO80 Chromatin Remodelling Coordinates Metabolic Homeostasis with Cell Division

molecular biology more details view paper
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