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Author: Emad Tajkhorshid

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  • All-time downloads: 8,356 (rank: 9,965 (tie) out of 380,908)
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    • biochemistry: 1,496 (rank: 1,443 (tie) out of 17,421)
    • biophysics: 3,846 (rank: 327 out of 15,713)
    • cancer biology: 482 (rank: 11,351 (tie) out of 26,203)
    • genetics: 353 (rank: 25,176 (tie) out of 35,213)
    • immunology: 609 (rank: 7,149 (tie) out of 20,681)
    • neuroscience: 1,570 (rank: 9,812 (tie) out of 63,955)

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Preprints

Mechanism of gating and partial agonist action in the glycine receptor

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Activation and desensitization mechanism of AMPA receptor-TARP complex by cryo-EM

biophysics more details view paper
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CryoFold: Ab-initio structure determination from electron density maps using molecular dynamics

biophysics more details view paper
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Aβ(1-42) tetramer and octamer structures reveal edge pores as a mechanism for membrane damage

biophysics more details view paper
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The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

cancer biology more details view paper
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The Structures of Secretory and Dimeric Immunoglobulin A

immunology more details view paper
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Glutamate transporters contain a conserved chloride channel with two hydrophobic gates

biophysics more details view paper
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A Network of Phosphatidylinositol 4,5-bisphosphate Binding Sites Regulate Gating of the Ca2+-activated Cl− Channel ANO1 (TMEM16A)

biophysics more details view paper
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Selective Permeability of Carboxysome Shell Pores to Anionic Molecules

biochemistry more details view paper
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Structural characterization of an intermediate reveals a unified mechanism for the CLC Cl−/H+ transport cycle

biophysics more details view paper
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Phosphatidic acid inhibits SNARE priming by inducing conformational changes in Sec18 protomers

biochemistry more details view paper
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Overexpression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy

genetics more details view paper
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Non-Canonical Binding of a Small Molecule to Sortilin Alters Cellular Trafficking of ApoB and PCSK9 in Liver Derived Cells

biochemistry more details view paper
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A statistical physics based approach to capture spurious solutions in AI-enhanced molecular dynamics

biophysics more details view paper
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Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

biochemistry more details view paper
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Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

biochemistry more details view paper
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Computational Recipe for Designing Antibodies against the Ebola Virus

immunology more details view paper
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