Author: Yu Chen

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Preprints

Selection and structural characterisation of anti-TREM2 scFvs that reduce levels of shed ectodomain

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Patient-derived mutations impact pathogenicity of SARS-CoV-2

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CoVID-19 in Japan: What could happen in the future?

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Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak

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Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset

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Functional SARS-CoV-2-specific immune memory persists after mild COVID-19

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Active or latent tuberculosis increases susceptibility to COVID-19 and disease severity

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ddPCR: a more sensitive and accurate tool for SARS-CoV-2 detection in low viral load specimens

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Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

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Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCoV, in the nasal tissue

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The level of plasma C-reactive protein is closely related to the liver injury in patients with COVID-19

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Co-infection of influenza A virus enhances SARS-CoV-2 infectivity

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TSA-Seq Mapping of Nuclear Genome Organization

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A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells

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Predictive engineering and optimization of tryptophan metabolism in yeast through a combination of mechanistic and machine learning models

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Evaluating brain cell marker genes based on differential gene expression and co-expression

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Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression

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Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage

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Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered: a single-center, retrospective, observational study

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TSA-Seq reveals a largely hardwired genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes

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Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells

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5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

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SPIN reveals genome-wide landscape of nuclear compartmentalization

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Questionnaire assessment helps the self-management of patients with inflammatory bowel disease during the outbreak of Coronavirus Disease 2019

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Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L

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Arabidopsis ATHB17 coordinates nuclear and plastidic photosynthesis gene expression in response to abiotic stress

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  • Site-wide: 26,662
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Role of Specialized mSWI/SNF Complexes in Prostate Cancer Lineage Plasticity

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Uveal Melanoma Oncogene CYSLTR2 Encodes a Constitutively Active GPCR Highly Biased Toward Gq Signaling

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Characterization and Variation of the Rhizosphere Fungal Community Structure of Cultivated Tetraploid Cotton

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  • Site-wide: 39,800
  • In ecology: 964
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Age groups that sustain resurging COVID-19 epidemics in the United States

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ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming

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Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities

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A novel xenograft model of human HCC in immunocompetent mouse

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Structure and function of accessory Sec proteins involved in the adhesin export pathway of Streptococcus gordonii

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Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo

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Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

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Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments

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A systematic dissection of human primary osteoblasts in vivo at single-cell resolution

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Bacillus cereus HS24 Suppresses Conidia Germination of Magnaporthe oryzae by Inhibiting the Ca2+ Signaling Pathway

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Loss of Adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

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An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity

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Suppressors of YpsA-mediated cell division inhibition in Bacillus subtilis

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Hsa-mir-210 as a novel signature predicts survival in lung squamous cell carcinoma using bioinformatics analysis

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SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data

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Preliminary Study of the Potential Mechanism of CTSD in the Aging Process of Sepiella japonica: Fundamental Function Analysis

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KIT ligand protects against both light-induced and genetic photoreceptor degeneration

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Secreted and cell surface proteome analysis of pathogenic Corynebacterium diphtheriae reveals proteins relevant to virulence

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Poly(A) binding protein is required for mRNP remodeling to form P-bodies in mammalian cells

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Cell group analysis reveals changes in upper-layer neurons associated with schizophrenia

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Agonal factors distort gene-expression patterns in human postmortem brains

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Natural genetic diversity in the potato resistance gene RB confers suppression avoidance from Phytophthora effector IPI-O4

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Paip2 associates with PABPC1 on mRNA, and may facilitate PABPC1 dissociation from mRNA upon deadenylation

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Brain transcriptional regulatory architecture and schizophrenia etiology converge between East Asian and European ancestral populations

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