Author: Yu Chen
- ORCiD: http://orcid.org/0000-0003-1933-8290
- Most recently observed institution: Eisai Inc
Rankings
- All-time downloads: 258,326 (rank: 137 )
- Categories:
- biochemistry: 667 (rank: 7,367 (tie) )
- bioengineering: 1,658 (rank: 1,573 (tie) )
- bioinformatics: 3,108 (rank: 3,978 )
- biophysics: 870 (rank: 5,194 (tie) )
- cancer biology: 3,062 (rank: 1,278 )
- cell biology: 3,560 (rank: 1,162 )
- ecology: 1,863 (rank: 1,556 (tie) )
- epidemiology: 44,216 (rank: 326 )
- gastroenterology: 895 (rank: 326 (tie) )
- genetics: 225 (rank: 35,431 (tie) )
- genomics: 4,971 (rank: 4,436 )
- immunology: 280 (rank: 22,201 (tie) )
- infectious diseases: 142,805 (rank: 113 )
- microbiology: 42,084 (rank: 243 )
- neuroscience: 1,525 (rank: 13,932 (tie) )
- pharmacology and toxicology: 4,084 (rank: 134 (tie) )
- plant biology: 886 (rank: 4,152 (tie) )
- respiratory medicine: 1,230 (rank: 708 (tie) )
- systems biology: 337 (rank: 10,098 (tie) )
Downloads per author, site-wide
Preprints
Selection and structural characterisation of anti-TREM2 scFvs that reduce levels of shed ectodomain
molecular biology more details view paperNo download data for this paper yet.
Patient-derived mutations impact pathogenicity of SARS-CoV-2
infectious diseases more details view paper- Downloaded 72,474 times
- Download rankings, all-time:
- Site-wide: 67
- In infectious diseases: 26
- Year to date:
- Site-wide: 758
- Since beginning of last month:
- Site-wide: 758
CoVID-19 in Japan: What could happen in the future?
epidemiology more details view paper- Downloaded 43,623 times
- Download rankings, all-time:
- Site-wide: 123
- In epidemiology: 31
- Year to date:
- Site-wide: 4,922
- Since beginning of last month:
- Site-wide: 4,922
Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak
microbiology more details view paper- Downloaded 37,932 times
- Download rankings, all-time:
- Site-wide: 145
- In microbiology: 13
- Year to date:
- Site-wide: 1,478
- Since beginning of last month:
- Site-wide: 1,478
Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset
infectious diseases more details view paper- Downloaded 33,017 times
- Download rankings, all-time:
- Site-wide: 180
- In infectious diseases: 71
- Year to date:
- Site-wide: 3,089
- Since beginning of last month:
- Site-wide: 3,089
Functional SARS-CoV-2-specific immune memory persists after mild COVID-19
infectious diseases more details view paper- Downloaded 13,500 times
- Download rankings, all-time:
- Site-wide: 478
- In infectious diseases: 164
- Year to date:
- Site-wide: 774
- Since beginning of last month:
- Site-wide: 774
Active or latent tuberculosis increases susceptibility to COVID-19 and disease severity
infectious diseases more details view paper- Downloaded 9,167 times
- Download rankings, all-time:
- Site-wide: 837
- In infectious diseases: 249
- Year to date:
- Site-wide: 1,268
- Since beginning of last month:
- Site-wide: 1,268
ddPCR: a more sensitive and accurate tool for SARS-CoV-2 detection in low viral load specimens
infectious diseases more details view paper- Downloaded 7,833 times
- Download rankings, all-time:
- Site-wide: 1,017
- In infectious diseases: 289
- Year to date:
- Site-wide: 5,571
- Since beginning of last month:
- Site-wide: 5,571
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
pharmacology and toxicology more details view paper- Downloaded 3,829 times
- Download rankings, all-time:
- Site-wide: 2,708
- In pharmacology and toxicology: 13
- Year to date:
- Site-wide: 6,061
- Since beginning of last month:
- Site-wide: 6,061
Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCoV, in the nasal tissue
infectious diseases more details view paper- Downloaded 3,430 times
- Download rankings, all-time:
- Site-wide: 3,191
- In infectious diseases: 588
- Year to date:
- Site-wide: 9,056
- Since beginning of last month:
- Site-wide: 9,056
The level of plasma C-reactive protein is closely related to the liver injury in patients with COVID-19
infectious diseases more details view paper- Downloaded 3,384 times
- Download rankings, all-time:
- Site-wide: 3,240
- In infectious diseases: 597
- Year to date:
- Site-wide: 13,299
- Since beginning of last month:
- Site-wide: 13,299
Co-infection of influenza A virus enhances SARS-CoV-2 infectivity
microbiology more details view paper- Downloaded 3,098 times
- Download rankings, all-time:
- Site-wide: 3,682
- In microbiology: 235
- Year to date:
- Site-wide: 11,675
- Since beginning of last month:
- Site-wide: 11,675
TSA-Seq Mapping of Nuclear Genome Organization
genomics more details view paper- Downloaded 2,649 times
- Download rankings, all-time:
- Site-wide: 4,609
- In genomics: 533
- Year to date:
- Site-wide: 58,924
- Since beginning of last month:
- Site-wide: 58,924
A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells
cell biology more details view paper- Downloaded 2,017 times
- Download rankings, all-time:
- Site-wide: 6,826
- In cell biology: 147
- Year to date:
- Site-wide: 4,679
- Since beginning of last month:
- Site-wide: 4,679
Predictive engineering and optimization of tryptophan metabolism in yeast through a combination of mechanistic and machine learning models
bioengineering more details view paper- Downloaded 1,658 times
- Download rankings, all-time:
- Site-wide: 9,224
- In bioengineering: 152
- Year to date:
- Site-wide: 28,842
- Since beginning of last month:
- Site-wide: 28,842
Evaluating brain cell marker genes based on differential gene expression and co-expression
neuroscience more details view paper- Downloaded 1,362 times
- Download rankings, all-time:
- Site-wide: 12,310
- In neuroscience: 1,437
- Year to date:
- Site-wide: 7,309
- Since beginning of last month:
- Site-wide: 7,309
Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression
bioinformatics more details view paper- Downloaded 1,288 times
- Download rankings, all-time:
- Site-wide: 13,380
- In bioinformatics: 1,654
- Year to date:
- Site-wide: 25,312
- Since beginning of last month:
- Site-wide: 25,312
Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage
ecology more details view paper- Downloaded 1,265 times
- Download rankings, all-time:
- Site-wide: 13,760
- In ecology: 220
- Year to date:
- Site-wide: 3,609
- Since beginning of last month:
- Site-wide: 3,609
Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered: a single-center, retrospective, observational study
respiratory medicine more details view paper- Downloaded 1,230 times
- Download rankings, all-time:
- Site-wide: 14,368
- In respiratory medicine: 48
- Year to date:
- Site-wide: 75,325
- Since beginning of last month:
- Site-wide: 75,325
TSA-Seq reveals a largely hardwired genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes
genomics more details view paper- Downloaded 1,148 times
- Download rankings, all-time:
- Site-wide: 15,962
- In genomics: 1,693
- Year to date:
- Site-wide: 22,305
- Since beginning of last month:
- Site-wide: 22,305
Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells
cell biology more details view paper- Downloaded 1,083 times
- Download rankings, all-time:
- Site-wide: 17,396
- In cell biology: 571
- Year to date:
- Site-wide: 7,748
- Since beginning of last month:
- Site-wide: 7,748
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages
genomics more details view paper- Downloaded 1,068 times
- Download rankings, all-time:
- Site-wide: 17,757
- In genomics: 1,842
- Year to date:
- Site-wide: 79,078
- Since beginning of last month:
- Site-wide: 79,078
SPIN reveals genome-wide landscape of nuclear compartmentalization
bioinformatics more details view paper- Downloaded 973 times
- Download rankings, all-time:
- Site-wide: 20,347
- In bioinformatics: 2,453
- Year to date:
- Site-wide: 21,893
- Since beginning of last month:
- Site-wide: 21,893
Questionnaire assessment helps the self-management of patients with inflammatory bowel disease during the outbreak of Coronavirus Disease 2019
gastroenterology more details view paper- Downloaded 895 times
- Download rankings, all-time:
- Site-wide: 22,999
- In gastroenterology: 18
- Year to date:
- Site-wide: 21,426
- Since beginning of last month:
- Site-wide: 21,426
Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L
biophysics more details view paper- Downloaded 870 times
- Download rankings, all-time:
- Site-wide: 23,926
- In biophysics: 678
- Year to date:
- Site-wide: 9,873
- Since beginning of last month:
- Site-wide: 9,873
Arabidopsis ATHB17 coordinates nuclear and plastidic photosynthesis gene expression in response to abiotic stress
plant biology more details view paper- Downloaded 805 times
- Download rankings, all-time:
- Site-wide: 26,662
- In plant biology: 476
- Year to date:
- Site-wide: 58,225
- Since beginning of last month:
- Site-wide: 58,225
Role of Specialized mSWI/SNF Complexes in Prostate Cancer Lineage Plasticity
cancer biology more details view paper- Downloaded 771 times
- Download rankings, all-time:
- Site-wide: 28,264
- In cancer biology: 739
- Year to date:
- Site-wide: 45,250
- Since beginning of last month:
- Site-wide: 45,250
Uveal Melanoma Oncogene CYSLTR2 Encodes a Constitutively Active GPCR Highly Biased Toward Gq Signaling
cancer biology more details view paper- Downloaded 750 times
- Download rankings, all-time:
- Site-wide: 29,418
- In cancer biology: 778
- Year to date:
- Site-wide: 78,369
- Since beginning of last month:
- Site-wide: 78,369
Characterization and Variation of the Rhizosphere Fungal Community Structure of Cultivated Tetraploid Cotton
ecology more details view paper- Downloaded 598 times
- Download rankings, all-time:
- Site-wide: 39,800
- In ecology: 964
- Year to date:
- Site-wide: 41,530
- Since beginning of last month:
- Site-wide: 41,530
Age groups that sustain resurging COVID-19 epidemics in the United States
epidemiology more details view paper- Downloaded 593 times
- Download rankings, all-time:
- Site-wide: 40,224
- In epidemiology: 1,894
- Year to date:
- Site-wide: 9,339
- Since beginning of last month:
- Site-wide: 9,339
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming
cancer biology more details view paper- Downloaded 560 times
- Download rankings, all-time:
- Site-wide: 43,211
- In cancer biology: 1,206
- Year to date:
- Site-wide: 45,011
- Since beginning of last month:
- Site-wide: 45,011
Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities
cancer biology more details view paper- Downloaded 506 times
- Download rankings, all-time:
- Site-wide: 48,784
- In cancer biology: 1,345
- Year to date:
- Site-wide: 6,334
- Since beginning of last month:
- Site-wide: 6,334
A novel xenograft model of human HCC in immunocompetent mouse
cancer biology more details view paper- Downloaded 475 times
- Download rankings, all-time:
- Site-wide: 52,402
- In cancer biology: 1,457
- Year to date:
- Site-wide: 22,925
- Since beginning of last month:
- Site-wide: 22,925
Structure and function of accessory Sec proteins involved in the adhesin export pathway of Streptococcus gordonii
biochemistry more details view paper- Downloaded 467 times
- Download rankings, all-time:
- Site-wide: 53,445
- In biochemistry: 1,410
- Year to date:
- Site-wide: 112,717
- Since beginning of last month:
- Site-wide: 112,717
Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo
cell biology more details view paper- Downloaded 460 times
- Download rankings, all-time:
- Site-wide: 54,295
- In cell biology: 2,384
- Year to date:
- Site-wide: 74,614
- Since beginning of last month:
- Site-wide: 74,614
Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide
microbiology more details view paper- Downloaded 374 times
- Download rankings, all-time:
- Site-wide: 66,949
- In microbiology: 4,526
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: None
Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments
systems biology more details view paper- Downloaded 337 times
- Download rankings, all-time:
- Site-wide: 73,091
- In systems biology: 1,773
- Year to date:
- Site-wide: 24,828
- Since beginning of last month:
- Site-wide: 24,828
A systematic dissection of human primary osteoblasts in vivo at single-cell resolution
bioinformatics more details view paper- Downloaded 333 times
- Download rankings, all-time:
- Site-wide: 73,978
- In bioinformatics: 6,911
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: None
Bacillus cereus HS24 Suppresses Conidia Germination of Magnaporthe oryzae by Inhibiting the Ca2+ Signaling Pathway
microbiology more details view paper- Downloaded 312 times
- Download rankings, all-time:
- Site-wide: 77,805
- In microbiology: 5,436
- Year to date:
- Site-wide: 90,789
- Since beginning of last month:
- Site-wide: 90,789
Loss of Adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22
immunology more details view paper- Downloaded 280 times
- Download rankings, all-time:
- Site-wide: 84,328
- In immunology: 2,306
- Year to date:
- Site-wide: 118,516
- Since beginning of last month:
- Site-wide: 118,516
An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity
pharmacology and toxicology more details view paper- Downloaded 255 times
- Download rankings, all-time:
- Site-wide: 89,714
- In pharmacology and toxicology: 625
- Year to date:
- Site-wide: 12,524
- Since beginning of last month:
- Site-wide: 12,524
Suppressors of YpsA-mediated cell division inhibition in Bacillus subtilis
microbiology more details view paper- Downloaded 241 times
- Download rankings, all-time:
- Site-wide: 92,583
- In microbiology: 6,698
- Year to date:
- Site-wide: 115,132
- Since beginning of last month:
- Site-wide: 115,132
Hsa-mir-210 as a novel signature predicts survival in lung squamous cell carcinoma using bioinformatics analysis
bioinformatics more details view paper- Downloaded 222 times
- Download rankings, all-time:
- Site-wide: 96,632
- In bioinformatics: 8,376
- Year to date:
- Site-wide: 117,005
- Since beginning of last month:
- Site-wide: 117,005
SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data
bioinformatics more details view paper- Downloaded 205 times
- Download rankings, all-time:
- Site-wide: 100,426
- In bioinformatics: 8,601
- Year to date:
- Site-wide: 66,401
- Since beginning of last month:
- Site-wide: 66,401
Preliminary Study of the Potential Mechanism of CTSD in the Aging Process of Sepiella japonica: Fundamental Function Analysis
genetics more details view paper- Downloaded 178 times
- Download rankings, all-time:
- Site-wide: 106,184
- In genetics: 4,734
- Year to date:
- Site-wide: 119,609
- Since beginning of last month:
- Site-wide: 119,609
KIT ligand protects against both light-induced and genetic photoreceptor degeneration
neuroscience more details view paper- Downloaded 163 times
- Download rankings, all-time:
- Site-wide: 109,064
- In neuroscience: 16,990
- Year to date:
- Site-wide: 121,293
- Since beginning of last month:
- Site-wide: 121,293
Secreted and cell surface proteome analysis of pathogenic Corynebacterium diphtheriae reveals proteins relevant to virulence
microbiology more details view paper- Downloaded 127 times
- Download rankings, all-time:
- Site-wide: 115,944
- In microbiology: 8,819
- Year to date:
- Site-wide: 66,084
- Since beginning of last month:
- Site-wide: 66,084
Poly(A) binding protein is required for mRNP remodeling to form P-bodies in mammalian cells
biochemistry more details view paper- Downloaded 123 times
- Download rankings, all-time:
- Site-wide: 116,692
- In biochemistry: 3,520
- Year to date:
- Site-wide: 8,178
- Since beginning of last month:
- Site-wide: 8,178
Cell group analysis reveals changes in upper-layer neurons associated with schizophrenia
genomics more details view paper- Downloaded 106 times
- Download rankings, all-time:
- Site-wide: 119,759
- In genomics: 6,537
- Year to date:
- Site-wide: 89,254
- Since beginning of last month:
- Site-wide: 89,254
Agonal factors distort gene-expression patterns in human postmortem brains
bioinformatics more details view paper- Downloaded 87 times
- Download rankings, all-time:
- Site-wide: 122,763
- In bioinformatics: 9,877
- Year to date:
- Site-wide: 93,778
- Since beginning of last month:
- Site-wide: 93,778
Natural genetic diversity in the potato resistance gene RB confers suppression avoidance from Phytophthora effector IPI-O4
plant biology more details view paper- Downloaded 81 times
- Download rankings, all-time:
- Site-wide: 123,613
- In plant biology: 3,495
- Year to date:
- Site-wide: 49,801
- Since beginning of last month:
- Site-wide: 49,801
Paip2 associates with PABPC1 on mRNA, and may facilitate PABPC1 dissociation from mRNA upon deadenylation
biochemistry more details view paper- Downloaded 77 times
- Download rankings, all-time:
- Site-wide: 124,158
- In biochemistry: 3,748
- Year to date:
- Site-wide: 14,628
- Since beginning of last month:
- Site-wide: 14,628
Brain transcriptional regulatory architecture and schizophrenia etiology converge between East Asian and European ancestral populations
genetics more details view paper- Downloaded 47 times
- Download rankings, all-time:
- Site-wide: 126,799
- In genetics: 5,321
- Year to date:
- Site-wide: 25,466
- Since beginning of last month:
- Site-wide: 25,466
PanLingua
News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!