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Author: Patrick R. Griffin

Rankings

  • All-time downloads: 7,594 (rank: 13,190 (tie) out of 426,130)
  • Categories:
    • biochemistry: 4,849 (rank: 330 out of 20,760)
    • biophysics: 1,676 (rank: 1,819 out of 18,184)
    • cancer biology: 687 (rank: 9,401 (tie) out of 30,395)
    • cell biology: 227 (rank: 25,539 (tie) out of 32,874)
    • pharmacology and toxicology: 65 (rank: 6,139 (tie) out of 6,400)
    • physiology: 90 (rank: 8,638 (tie) out of 9,536)

Downloads per author, site-wide

Preprints

Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d

biochemistry more details view paper
  • Downloaded 4,086 times
  • Download rankings, all-time:
    • Site-wide: 1,254 out of 100,883
    • In biochemistry: 33 out of 3,446
  • Year to date:
    • Site-wide: 3,155 out of 100,883
  • Since beginning of last month:
    • Site-wide: 5,810 out of 100,883

Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

biophysics more details view paper
  • Downloaded 1,048 times
  • Download rankings, all-time:
    • Site-wide: 12,423 out of 100,883
    • In biophysics: 397 out of 4,449
  • Year to date:
    • Site-wide: 24,269 out of 100,883
  • Since beginning of last month:
    • Site-wide: 16,387 out of 100,883

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

cancer biology more details view paper
  • Downloaded 541 times
  • Download rankings, all-time:
    • Site-wide: 32,931 out of 100,883
    • In cancer biology: 1,056 out of 3,613
  • Year to date:
    • Site-wide: 41,878 out of 100,883
  • Since beginning of last month:
    • Site-wide: 39,360 out of 100,883

Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

biochemistry more details view paper
  • Downloaded 411 times
  • Download rankings, all-time:
    • Site-wide: 45,623 out of 100,883
    • In biochemistry: 1,358 out of 3,446
  • Year to date:
    • Site-wide: 65,965 out of 100,883
  • Since beginning of last month:
    • Site-wide: 54,875 out of 100,883

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calmodulin (CaM) Effector in Mouse Brain

biochemistry more details view paper
  • Downloaded 352 times
  • Download rankings, all-time:
    • Site-wide: 53,280 out of 100,883
    • In biochemistry: 1,620 out of 3,446
  • Year to date:
    • Site-wide: 84,822 out of 100,883
  • Since beginning of last month:
    • Site-wide: 79,744 out of 100,883

Quantitative Structural Assessment of Graded Receptor Agonism

biophysics more details view paper
  • Downloaded 348 times
  • Download rankings, all-time:
    • Site-wide: 53,878 out of 100,883
    • In biophysics: 2,255 out of 4,449
  • Year to date:
    • Site-wide: 53,010 out of 100,883
  • Since beginning of last month:
    • Site-wide: 68,595 out of 100,883

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

biophysics more details view paper
  • Downloaded 280 times
  • Download rankings, all-time:
    • Site-wide: 64,351 out of 100,883
    • In biophysics: 2,765 out of 4,449
  • Year to date:
    • Site-wide: 71,626 out of 100,883
  • Since beginning of last month:
    • Site-wide: 55,251 out of 100,883

A Simple and Robust Cell Based Assay for the Discovery of Novel Cytokinesis Inhibitors

cell biology more details view paper
  • Downloaded 227 times
  • Download rankings, all-time:
    • Site-wide: 73,670 out of 100,883
    • In cell biology: 3,834 out of 5,217
  • Year to date:
    • Site-wide: 24,501 out of 100,883
  • Since beginning of last month:
    • Site-wide: 39,479 out of 100,883

Dual-mechanism estrogen receptor inhibitors expand the repertoire of anti-hormone therapy for breast cancer

cancer biology more details view paper
  • Downloaded 146 times
  • Download rankings, all-time:
    • Site-wide: 87,327 out of 100,883
    • In cancer biology: 3,002 out of 3,613
  • Year to date:
    • Site-wide: 42,865 out of 100,883
  • Since beginning of last month:
    • Site-wide: 26,018 out of 100,883

PPARG in osteocytes is essential for sclerostin expression, bone mass, marrow adiposity and TZD-induced bone loss

physiology more details view paper
  • Downloaded 90 times
  • Download rankings, all-time:
    • Site-wide: 94,277 out of 100,883
    • In physiology: 1,259 out of 1,437
  • Year to date:
    • Site-wide: 68,841 out of 100,883
  • Since beginning of last month:
    • Site-wide: 7,369 out of 100,883

Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor

pharmacology and toxicology more details view paper
  • Downloaded 65 times
  • Download rankings, all-time:
    • Site-wide: 96,749 out of 100,883
    • In pharmacology and toxicology: 925 out of 981
  • Year to date:
    • Site-wide: 86,374 out of 100,883
  • Since beginning of last month:
    • Site-wide: 49,270 out of 100,883

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News

  • 20 Oct 2020: Support for sorting preprints using Twitter activity has been removed, at least temporarily, until a new source of social media activity data becomes available.
  • 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
  • 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
  • 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
  • 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
  • 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
  • 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
  • 22 Jan 2019: Nature just published an article about Rxivist and our data.
  • 13 Jan 2019: The Rxivist preprint is live!