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Author: Yukinori Okada

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  • All-time downloads: 22,641 (rank: 1,584 out of 338,671)
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    • genetics: 22,641 (rank: 234 out of 32,619)

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Preprints

Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes

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Partitioning heritability by functional category using GWAS summary statistics

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    • In genetics: 27 out of 4,201
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    • Site-wide: 4,150 out of 78,222

Current clinical use of polygenic scores will risk exacerbating health disparities

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    • In genetics: 44 out of 4,201
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    • Site-wide: 2,636 out of 78,222

Genetic analyses identify widespread sex-differential participation bias

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Large scale genome-wide association study in a Japanese population identified 45 novel susceptibility loci for 22 diseases

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    • In genetics: 479 out of 4,201
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    • Site-wide: 1,915 out of 78,222
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    • Site-wide: 2,337 out of 78,222

Identification of type 2 diabetes loci in 433,540 East Asian individuals

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    • In genetics: 524 out of 4,201
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    • Site-wide: 1,681 out of 78,222

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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    • In genetics: 555 out of 4,201
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IMPACT: Genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors

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    • In genetics: 670 out of 4,201
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Population-specific causal disease effect sizes in functionally important regions impacted by selection

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    • In genetics: 923 out of 4,201
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Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan

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    • In genetics: 1,066 out of 4,201
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    • Site-wide: 2,694 out of 78,222
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    • Site-wide: 1,785 out of 78,222

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

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    • In genetics: 1,225 out of 4,201
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    • Site-wide: 48,658 out of 78,222

The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions.

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  • Downloaded 396 times
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    • Site-wide: 34,221 out of 78,222
    • In genetics: 2,087 out of 4,201
  • Year to date:
    • Site-wide: 40,741 out of 78,222
  • Since beginning of last month:
    • Site-wide: 22,920 out of 78,222

Genome-wide association meta-analysis identifies novel GP2 gene risk variants for pancreatic cancer in the Japanese population

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    • In genetics: 2,379 out of 4,201
  • Year to date:
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    • Site-wide: 47,427 out of 78,222

Evidence of polygenic adaptation at height-associated loci in mainland Europeans and Sardinians

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    • In genetics: 2,458 out of 4,201
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    • Site-wide: 18,437 out of 78,222
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    • Site-wide: 20,047 out of 78,222

Mechanistic characterization of RASGRP1 variants identifies an hnRNP K-regulated transcriptional enhancer contributing to SLE susceptibility

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    • In genetics: 3,162 out of 4,201
  • Year to date:
    • Site-wide: 56,782 out of 78,222
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    • Site-wide: 64,400 out of 78,222

Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.

genetics more details view paper
  • Downloaded 181 times
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    • Site-wide: 62,196 out of 78,222
    • In genetics: 3,515 out of 4,201
  • Year to date:
    • Site-wide: 37,806 out of 78,222
  • Since beginning of last month:
    • Site-wide: 44,001 out of 78,222

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