Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 70,653 bioRxiv papers from 308,421 authors.

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Preprints

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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  • In genomics: 282 out of 4,718
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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • In genetics: 134 out of 3,916
• Year to date:
  • Site-wide: 18,523 out of 70,658
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  • Site-wide: 34,867 out of 70,658

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • In genetics: 285 out of 3,916
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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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  • In genetics: 373 out of 3,916
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Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

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  • In genetics: 412 out of 3,916
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New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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  • In genomics: 914 out of 4,718
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  • Site-wide: 16,832 out of 70,658

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • In genetics: 449 out of 3,916
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  • Site-wide: 3,547 out of 70,658

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • In genetics: 454 out of 3,916
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  • Site-wide: 15,500 out of 70,658

Integrative cross tissue analysis of gene expression identifies novel type 2 diabetes genes

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  • In genetics: 481 out of 3,916
• Year to date:
  • Site-wide: 36,947 out of 70,658
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  • Site-wide: 25,087 out of 70,658

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • In genetics: 486 out of 3,916
• Year to date:
  • Site-wide: 2,328 out of 70,658
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  • Site-wide: 1,870 out of 70,658

Identification of type 2 diabetes loci in 433,540 East Asian individuals

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  • In genetics: 635 out of 3,916
• Year to date:
  • Site-wide: 9,759 out of 70,658
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  • Site-wide: 6,267 out of 70,658

Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis

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  • Site-wide: 10,966 out of 70,658
  • In genomics: 1,585 out of 4,718
• Year to date:
  • Site-wide: 12,322 out of 70,658
• Since beginning of last month:
  • Site-wide: 3,812 out of 70,658

The genetic architecture of sporadic and recurrent miscarriage

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  • Site-wide: 13,451 out of 70,658
  • In genetics: 923 out of 3,916
• Year to date:
  • Site-wide: 14,572 out of 70,658
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  • Site-wide: 12,924 out of 70,658

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 16,053 out of 70,658
  • In genetics: 1,091 out of 3,916
• Year to date:
  • Site-wide: 18,145 out of 70,658
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  • Site-wide: 19,298 out of 70,658

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 621 times
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  • Site-wide: 16,992 out of 70,658
  • In genomics: 2,107 out of 4,718
• Year to date:
  • Site-wide: 64,071 out of 70,658
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  • Site-wide: 23,643 out of 70,658

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

• Downloaded 617 times
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  • Site-wide: 17,141 out of 70,658
  • In genetics: 1,158 out of 3,916
• Year to date:
  • Site-wide: 64,067 out of 70,658
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  • Site-wide: 31,625 out of 70,658

MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

• Downloaded 551 times
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  • Site-wide: 20,056 out of 70,658
  • In bioinformatics: 2,946 out of 6,919
• Year to date:
  • Site-wide: 25,243 out of 70,658
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  • Site-wide: 36,282 out of 70,658

Genome Wide Association Scan identifies new variants associated with a cognitive predictor of dyslexia.

• Downloaded 495 times
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  • Site-wide: 22,982 out of 70,658
  • In genomics: 2,547 out of 4,718
• Year to date:
  • Site-wide: 57,189 out of 70,658
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  • Site-wide: 38,184 out of 70,658

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 398 times
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  • Site-wide: 29,619 out of 70,658
  • In genetics: 1,875 out of 3,916
• Year to date:
  • Site-wide: 55,223 out of 70,658
• Since beginning of last month:
  • Site-wide: 39,472 out of 70,658

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 390 times
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  • Site-wide: 30,225 out of 70,658
  • In genetics: 1,909 out of 3,916
• Year to date:
  • Site-wide: 7,865 out of 70,658
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  • Site-wide: 8,463 out of 70,658

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 361 times
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  • Site-wide: 32,767 out of 70,658
  • In genetics: 2,056 out of 3,916
• Year to date:
  • Site-wide: 20,116 out of 70,658
• Since beginning of last month:
  • Site-wide: 15,156 out of 70,658

Simultaneous analysis of open chromatin, promoter interactions and gene expression in stimulated T cells implicates causal genes for rheumatoid arthritis

• Downloaded 265 times
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  • Site-wide: 43,029 out of 70,658
  • In genomics: 3,722 out of 4,718
• Year to date:
  • Site-wide: 22,885 out of 70,658
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  • Site-wide: 10,069 out of 70,658

methylSCOPA and META-methylSCOPA: software for the analysis and aggregation of epigenome-wide association studies of multiple correlated phenotypes

• Downloaded 194 times
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  • Site-wide: 52,638 out of 70,658
  • In bioinformatics: 5,754 out of 6,919
• Year to date:
  • Site-wide: 33,792 out of 70,658
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  • Site-wide: 29,472 out of 70,658

Chromatin-based techniques map DNA interaction landscapes in psoriasis susceptibility loci and highlight KLF4 as a target gene in 9q31

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  • Site-wide: 63,022 out of 70,658
  • In genomics: 4,515 out of 4,718
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  • Site-wide: 24,656 out of 70,658
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  • Site-wide: 25,492 out of 70,658