Author: Xin He

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Preprints

Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism

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Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

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Limited contribution of rare, noncoding variation to autism spectrum disorder from sequencing of 2,076 genomes in quartet families

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Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

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A statistical framework for mapping risk genes from de novo mutations in whole-genome sequencing studies

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Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

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Ultra-high throughput multiplexing and sequencing of >500 bp amplicon regions on the Illumina HiSeq 2500 platform

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Post-transcriptionally impaired de novo mutations contribute to the genetic etiology of four neuropsychiatric disorders

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Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

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Model-based analysis of positive selection significantly expands the list of cancer driver genes, including RNA methyltransferases

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Integrative analysis of rare variants and pathway information shows convergent results between immune pathways, drug targets and epilepsy genes

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Allele-specific open chromatin in human iPSC neurons elucidates functional non-coding disease variants

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CCmed: cross-condition mediation analysis for identifying robust trans-eQTLs and assessing their effects on human traits

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mTADA: a framework for analyzing de novo mutations in multiple traits

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A Bayesian method for rare variant analysis using functional annotations and its application to Autism

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Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth

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Effects of Antipsychotic Drugs and Potassium Channel Modulators on Cognition-related Local Field Potential Spectral Properties in Mouse Hippocampus and Frontal Cortex

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A Computer-aided Method for Identifying the Presence of Softwood Growth Ring Boundaries

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Eye-specific voluntary attention can induce a shift of perceptual ocular dominance

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