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Author: Naomi R. Wray

Rankings

  • All-time downloads: 138,556 (rank: 1,215 )
  • Categories:
    • bioinformatics: 4,249 (rank: 4,746 )
    • epidemiology: 983 (rank: 16,489 (tie) )
    • genetic and genomic medicine: 7,126 (rank: 443 )
    • genetics: 93,566 (rank: 29 )
    • genomics: 21,894 (rank: 793 )
    • neurology: 3,050 (rank: 612 (tie) )
    • neuroscience: 2,052 (rank: 19,387 (tie) )
    • psychiatry and clinical psychology: 4,675 (rank: 254 )

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
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Genetic Consequences of Social Stratification in Great Britain

genetics more details view paper
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    • In genetics: 33
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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,744 times
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    • In genetics: 45
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New mutations, old statistical challenges

genetics more details view paper
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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,875 times
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    • Site-wide: 3,617
    • In genetics: 100
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Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

genomics more details view paper
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A resource-efficient tool for mixed model association analysis of large-scale data

genetics more details view paper
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
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    • In psychiatry and clinical psychology: 20
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Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

genetics more details view paper
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    • Site-wide: 6,167
    • In genetics: 205
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Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
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Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

genetics more details view paper
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    • In genetics: 218
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A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

genetic and genomic medicine more details view paper
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    • Site-wide: 6,524
    • In genetic and genomic medicine: 36
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Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 3,066 times
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    • Site-wide: 7,066
    • In genetics: 256
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A comparative study of techniques for differential expression analysis on RNA-Seq data

bioinformatics more details view paper
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    • Site-wide: 8,519
    • In bioinformatics: 865
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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
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    • Site-wide: 8,575
    • In genomics: 802
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Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

neurology more details view paper
  • Downloaded 2,240 times
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    • Site-wide: 11,311
    • In neurology: 35
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GWAS on family history of Alzheimer's disease

genetics more details view paper
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
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Causal associations between risk factors and common diseases inferred from GWAS summary data

genetics more details view paper
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    • Site-wide: 14,719
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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
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    • Site-wide: 15,452
    • In genetics: 619
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Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
  • Downloaded 1,733 times
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    • Site-wide: 16,764
    • In genetics: 679
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
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Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
  • Downloaded 1,617 times
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    • Site-wide: 18,691
    • In genetics: 759
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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,563 times
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    • Site-wide: 19,716
    • In bioinformatics: 2,157
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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

genetics more details view paper
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    • Site-wide: 20,633
    • In genetics: 830
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Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,427 times
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    • Site-wide: 22,842
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Genetic Association Study of Childhood Aggression across raters, instruments and age

genomics more details view paper
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    • Site-wide: 22,943
    • In genomics: 2,000
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Imprint of Assortative Mating on the Human Genome

genetics more details view paper
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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
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    • Site-wide: 23,693
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Cross-disorder GWAS meta-analysis for Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Obsessive Compulsive Disorder, and Tourette Syndrome

genetics more details view paper
  • Downloaded 1,218 times
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    • Site-wide: 29,350
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Estimation of genetic correlation using linkage disequilibrium score regression and genomic restricted maximum likelihood

genetics more details view paper
  • Downloaded 1,209 times
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    • Site-wide: 29,701
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Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases

genomics more details view paper
  • Downloaded 1,183 times
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Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
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Epigenetic prediction of complex traits and death

genomics more details view paper
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Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference

genetics more details view paper
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    • Site-wide: 38,178
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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

genetics more details view paper
  • Downloaded 979 times
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    • Site-wide: 41,248
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Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

genetic and genomic medicine more details view paper
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Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

genomics more details view paper
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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 938 times
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    • Site-wide: 44,052
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Widespread associations between grey matter structure and the human phenome

neuroscience more details view paper
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Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

genetics more details view paper
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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

genetics more details view paper
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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
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The Australian Genetics of Depression Study: Study Description and Sample Characteristics

genetics more details view paper
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Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

genetics more details view paper
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Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

genetics more details view paper
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Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways

neurology more details view paper
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    • Site-wide: 54,016
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Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model

genetics more details view paper
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Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

genetics more details view paper
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

genetics more details view paper
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    • Site-wide: 64,750
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Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries

genetics more details view paper
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    • Site-wide: 65,074
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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

psychiatry and clinical psychology more details view paper
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    • Site-wide: 66,291
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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
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Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

genetics more details view paper
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Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
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Comprehensive genetic analysis of the human lipidome identifies novel loci controlling lipid homeostasis with links to coronary artery disease

genetic and genomic medicine more details view paper
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mBAT-combo: a more powerful test to detect gene-trait associations from GWAS data

genetics more details view paper
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A parsimonious model for mass-univariate vertex-wise analysis

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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
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Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

epidemiology more details view paper
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Age at first birth in women is genetically associated with increased risk of schizophrenia

genetics more details view paper
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The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

genetic and genomic medicine more details view paper
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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

neuroscience more details view paper
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A better design for stratified medicine based on genomic prediction

genetics more details view paper
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Gene expression and RNA splicing explain large proportions of the heritability for complex traits in cattle

genomics more details view paper
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Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

genetic and genomic medicine more details view paper
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Significance tests for R2 of out-of-sample prediction using polygenic scores

genetics more details view paper
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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

epidemiology more details view paper
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Understanding genetic risk factors for common side effects of antidepressant medications

psychiatry and clinical psychology more details view paper
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Phenotypic and genetic factors associated with differential consent to record linkage for prescription history in the Australian Genetics of Depression Study

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