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Author: Naomi R. Wray

Rankings

  • All-time downloads: 114,992 (rank: 872 )
  • Categories:
    • bioinformatics: 3,903 (rank: 3,336 (tie) )
    • epidemiology: 518 (rank: 15,449 (tie) )
    • genetic and genomic medicine: 3,133 (rank: 431 )
    • genetics: 82,620 (rank: 36 )
    • genomics: 19,088 (rank: 677 )
    • neurology: 1,173 (rank: 809 (tie) )
    • neuroscience: 1,462 (rank: 16,559 (tie) )
    • psychiatry and clinical psychology: 3,095 (rank: 235 (tie) )

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
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Genetic Consequences of Social Stratification in Great Britain

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    • In genetics: 34
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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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    • Site-wide: 1,280
    • In genetics: 39
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New mutations, old statistical challenges

genetics more details view paper
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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,581 times
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    • Site-wide: 2,433
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Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

genomics more details view paper
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Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

genetics more details view paper
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Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
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Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

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A resource-efficient tool for mixed model association analysis of large-scale data

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    • Site-wide: 4,748
    • In genetics: 204
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Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,795 times
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    • Site-wide: 4,930
    • In genetics: 211
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

psychiatry and clinical psychology more details view paper
  • Downloaded 2,686 times
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A comparative study of techniques for differential expression analysis on RNA-Seq data

bioinformatics more details view paper
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    • In bioinformatics: 603
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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
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    • Site-wide: 5,708
    • In genomics: 625
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GWAS on family history of Alzheimer's disease

genetics more details view paper
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    • Site-wide: 8,037
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
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    • Site-wide: 9,318
    • In genetics: 425
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Causal associations between risk factors and common diseases inferred from GWAS summary data

genetics more details view paper
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    • In genetics: 436
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A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 36
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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
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    • Site-wide: 11,680
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Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
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    • Site-wide: 11,943
    • In genetics: 562
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,469 times
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    • In genomics: 1,347
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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

genetics more details view paper
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    • Site-wide: 13,323
    • In genetics: 634
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Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
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    • Site-wide: 14,363
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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,341 times
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    • Site-wide: 14,645
    • In bioinformatics: 1,743
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Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,334 times
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Imprint of Assortative Mating on the Human Genome

genetics more details view paper
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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
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    • Site-wide: 16,624
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Estimation of genetic correlation using linkage disequilibrium score regression and genomic restricted maximum likelihood

genetics more details view paper
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Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases

genomics more details view paper
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Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
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Epigenetic prediction of complex traits and death

genomics more details view paper
  • Downloaded 1,019 times
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Genetic Association Study of Childhood Aggression across raters, instruments and age

genomics more details view paper
  • Downloaded 992 times
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Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

neurology more details view paper
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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

genetics more details view paper
  • Downloaded 857 times
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    • Site-wide: 28,172
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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

genetics more details view paper
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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
  • Downloaded 813 times
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    • Site-wide: 30,319
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Cross-disorder GWAS meta-analysis for Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Obsessive Compulsive Disorder, and Tourette Syndrome

genetics more details view paper
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Widespread associations between grey matter structure and the human phenome

neuroscience more details view paper
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Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

genetics more details view paper
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Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

genomics more details view paper
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Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

genetics more details view paper
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Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model

genetics more details view paper
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The Australian Genetics of Depression Study: Study Description and Sample Characteristics

genetics more details view paper
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Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

genetic and genomic medicine more details view paper
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Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

genetics more details view paper
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    • Site-wide: 42,838
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    • Site-wide: 16,203
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

genetics more details view paper
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Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

genetics more details view paper
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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 562 times
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Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
  • Downloaded 556 times
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Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

genetics more details view paper
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Age at first birth in women is genetically associated with increased risk of schizophrenia

genetics more details view paper
  • Downloaded 502 times
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    • Site-wide: 56,306
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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
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A better design for stratified medicine based on genomic prediction

genetics more details view paper
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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

psychiatry and clinical psychology more details view paper
  • Downloaded 409 times
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    • Site-wide: 70,027
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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

neuroscience more details view paper
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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

epidemiology more details view paper
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A parsimonious model for mass-univariate vertex-wise analysis

neuroscience more details view paper
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Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

epidemiology more details view paper
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Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways

neurology more details view paper
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Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

genetic and genomic medicine more details view paper
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