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Author: Timothy M Frayling

Rankings

  • All-time downloads: 56,677 (rank: 2,859 )
  • Categories:
    • epidemiology: 4,464 (rank: 3,193 )
    • genetic and genomic medicine: 1,771 (rank: 1,799 )
    • genetics: 39,879 (rank: 123 )
    • genomics: 8,909 (rank: 2,407 )
    • orthopedics: 516 (rank: 111 (tie) )
    • sexual and reproductive health: 1,138 (rank: 163 (tie) )

Downloads per author, site-wide

Preprints

Genetic Consequences of Social Stratification in Great Britain

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    • Site-wide: 1,260
    • In genetics: 34
  • Year to date:
    • Site-wide: 9,848
  • Since beginning of last month:
    • Site-wide: 34,205

Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

genetics more details view paper
  • Downloaded 6,761 times
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    • Site-wide: 1,549
    • In genetics: 46
  • Year to date:
    • Site-wide: 19,841
  • Since beginning of last month:
    • Site-wide: 60,982

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,277 times
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    • Site-wide: 4,265
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  • Year to date:
    • Site-wide: 83,079
  • Since beginning of last month:
    • Site-wide: 58,257

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

genetics more details view paper
  • Downloaded 2,402 times
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    • Site-wide: 6,691
    • In genetics: 293
  • Year to date:
    • Site-wide: 40,773
  • Since beginning of last month:
    • Site-wide: 34,406

Biological and clinical insights from genetics of insomnia symptoms

genomics more details view paper
  • Downloaded 2,179 times
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    • Site-wide: 7,718
    • In genomics: 805
  • Year to date:
    • Site-wide: 12,510
  • Since beginning of last month:
    • Site-wide: 21,666

Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 1,979 times
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    • Site-wide: 8,895
    • In epidemiology: 699
  • Year to date:
    • Site-wide: 87,238
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    • Site-wide: 23,363

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,881 times
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    • Site-wide: 9,587
    • In genetics: 417
  • Year to date:
    • Site-wide: 100,017
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Assessing the pathogenicity, penetrance and expressivity of putative disease-causing variants in a population setting

genetics more details view paper
  • Downloaded 1,876 times
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    • Site-wide: 9,622
    • In genetics: 419
  • Year to date:
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
  • Downloaded 1,726 times
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    • Site-wide: 10,867
    • In genetics: 481
  • Year to date:
    • Site-wide: 61,148
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Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases

genetics more details view paper
  • Downloaded 1,722 times
  • Download rankings, all-time:
    • Site-wide: 10,922
    • In genetics: 483
  • Year to date:
    • Site-wide: 49,003
  • Since beginning of last month:
    • Site-wide: 73,025

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

genetics more details view paper
  • Downloaded 1,662 times
  • Download rankings, all-time:
    • Site-wide: 11,492
    • In genetics: 515
  • Year to date:
    • Site-wide: 65,460
  • Since beginning of last month:
    • Site-wide: 60,434

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

genetics more details view paper
  • Downloaded 1,659 times
  • Download rankings, all-time:
    • Site-wide: 11,527
    • In genetics: 519
  • Year to date:
    • Site-wide: 114,661
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GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

genetics more details view paper
  • Downloaded 1,522 times
  • Download rankings, all-time:
    • Site-wide: 13,008
    • In genetics: 589
  • Year to date:
    • Site-wide: 97,851
  • Since beginning of last month:
    • Site-wide: 73,005

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,440 times
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    • Site-wide: 14,202
    • In genetics: 652
  • Year to date:
    • Site-wide: 103,642
  • Since beginning of last month:
    • Site-wide: 60,337

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,440 times
  • Download rankings, all-time:
    • Site-wide: 14,197
    • In genetic and genomic medicine: 60
  • Year to date:
    • Site-wide: 6,285
  • Since beginning of last month:
    • Site-wide: 13,572

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

genetics more details view paper
  • Downloaded 1,325 times
  • Download rankings, all-time:
    • Site-wide: 16,113
    • In genetics: 739
  • Year to date:
    • Site-wide: 84,503
  • Since beginning of last month:
    • Site-wide: 73,004

HUMAN LONGEVITY IS INFLUENCED BY MANY GENETIC VARIANTS: EVIDENCE FROM 75,000 UK BIOBANK PARTICIPANTS

genomics more details view paper
  • Downloaded 1,244 times
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    • Site-wide: 17,683
    • In genomics: 1,722
  • Year to date:
    • Site-wide: 127,517
  • Since beginning of last month:
    • Site-wide: 72,764

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

genetics more details view paper
  • Downloaded 1,224 times
  • Download rankings, all-time:
    • Site-wide: 18,127
    • In genetics: 843
  • Year to date:
    • Site-wide: 105,165
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    • Site-wide: None

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 1,138 times
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    • Site-wide: 20,197
    • In sexual and reproductive health: 15
  • Year to date:
    • Site-wide: 2,596
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    • Site-wide: 2,007

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 1,074 times
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    • Site-wide: 22,003
    • In genetics: 1,004
  • Year to date:
    • Site-wide: 10,170
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    • Site-wide: 43,841

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

genetics more details view paper
  • Downloaded 982 times
  • Download rankings, all-time:
    • Site-wide: 25,041
    • In genetics: 1,144
  • Year to date:
    • Site-wide: 84,412
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    • Site-wide: None

Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers

genomics more details view paper
  • Downloaded 972 times
  • Download rankings, all-time:
    • Site-wide: 25,467
    • In genomics: 2,364
  • Year to date:
    • Site-wide: 114,825
  • Since beginning of last month:
    • Site-wide: 24,485

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank study

genetics more details view paper
  • Downloaded 724 times
  • Download rankings, all-time:
    • Site-wide: 38,442
    • In genetics: 1,735
  • Year to date:
    • Site-wide: 81,701
  • Since beginning of last month:
    • Site-wide: 73,400

Quantifying the extent to which index event biases influence large genetic association studies

genetics more details view paper
  • Downloaded 702 times
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    • Site-wide: 40,064
    • In genetics: 1,802
  • Year to date:
    • Site-wide: 141,065
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    • Site-wide: None

Maximum likelihood method quantifies the overall contribution of gene-environment interaction to continuous traits: an application to complex traits in the UK Biobank

epidemiology more details view paper
  • Downloaded 698 times
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    • Site-wide: 40,422
    • In epidemiology: 1,996
  • Year to date:
    • Site-wide: 101,716
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    • Site-wide: 67,201

Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

genetics more details view paper
  • Downloaded 683 times
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    • Site-wide: 41,616
    • In genetics: 1,871
  • Year to date:
    • Site-wide: 127,662
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    • Site-wide: None

Genetic predictors of participation in optional components of UK Biobank

genetics more details view paper
  • Downloaded 657 times
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    • Site-wide: 43,733
    • In genetics: 1,957
  • Year to date:
    • Site-wide: 79,959
  • Since beginning of last month:
    • Site-wide: 14,967

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

genomics more details view paper
  • Downloaded 648 times
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    • Site-wide: 44,500
    • In genomics: 3,550
  • Year to date:
    • Site-wide: 120,005
  • Since beginning of last month:
    • Site-wide: 58,965

Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

genetics more details view paper
  • Downloaded 610 times
  • Download rankings, all-time:
    • Site-wide: 47,974
    • In genetics: 2,142
  • Year to date:
    • Site-wide: 107,118
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    • Site-wide: None

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
  • Downloaded 592 times
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    • Site-wide: 49,834
    • In genetics: 2,217
  • Year to date:
    • Site-wide: 128,130
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    • Site-wide: 73,383

Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

genomics more details view paper
  • Downloaded 589 times
  • Download rankings, all-time:
    • Site-wide: 50,170
    • In genomics: 3,857
  • Year to date:
    • Site-wide: 118,888
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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 588 times
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    • Site-wide: 50,296
    • In epidemiology: 2,345
  • Year to date:
    • Site-wide: 132,797
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    • Site-wide: 66,452

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively

genetics more details view paper
  • Downloaded 526 times
  • Download rankings, all-time:
    • Site-wide: 57,597
    • In genetics: 2,545
  • Year to date:
    • Site-wide: 124,110
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    • Site-wide: None

A genome wide association study of frozen shoulder identifies a common variant of WNT7B and diabetes as causal risk factors

orthopedics more details view paper
  • Downloaded 516 times
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    • Site-wide: 59,009
    • In orthopedics: 24
  • Year to date:
    • Site-wide: 10,806
  • Since beginning of last month:
    • Site-wide: 35,992

Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

epidemiology more details view paper
  • Downloaded 466 times
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    • Site-wide: 65,963
    • In epidemiology: 2,893
  • Year to date:
    • Site-wide: 134,606
  • Since beginning of last month:
    • Site-wide: 83,243

Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

epidemiology more details view paper
  • Downloaded 408 times
  • Download rankings, all-time:
    • Site-wide: 75,601
    • In epidemiology: 3,243
  • Year to date:
    • Site-wide: 54,359
  • Since beginning of last month:
    • Site-wide: 107,286

Higher maternal adiposity reduces offspring birth weight if associated with a metabolically favourable profile

genetic and genomic medicine more details view paper
  • Downloaded 226 times
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    • Site-wide: 115,516
    • In genetic and genomic medicine: 595
  • Year to date:
    • Site-wide: 97,287
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    • Site-wide: None

Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 203 times
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    • Site-wide: 121,171
    • In epidemiology: 5,073
  • Year to date:
    • Site-wide: 38,613
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    • Site-wide: 42,854

Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weight

genetics more details view paper
  • Downloaded 150 times
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    • Site-wide: 133,518
    • In genetics: 5,422
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    • Site-wide: 124,843
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Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study.

epidemiology more details view paper
  • Downloaded 122 times
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    • Site-wide: 139,617
    • In epidemiology: 5,752
  • Year to date:
    • Site-wide: 52,444
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    • Site-wide: 19,074

Associations of genetic scores for birth weight with newborn size and later Anthropometric traits and cardiometabolic risk markers in South Asians

genetic and genomic medicine more details view paper
  • Downloaded 105 times
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    • Site-wide: 142,881
    • In genetic and genomic medicine: 806
  • Year to date:
    • Site-wide: 60,226
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