Author: Gregory P. Way

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Preprints

Opportunities And Obstacles For Deep Learning In Biology And Medicine

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  • Site-wide: 3,230
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Extracting a Biologically Relevant Latent Space from Cancer Transcriptomes with Variational Autoencoders

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  • Site-wide: 3,430
  • In bioinformatics: 256
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Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

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  • In genomics: 852
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Predicting cell health phenotypes using image-based morphology profiling

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  • Site-wide: 14,435
  • In bioinformatics: 1,552
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Morphology and gene expression profiling provide complementary information for mapping cell state

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  • Site-wide: 15,096
  • In bioinformatics: 2,172
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Sequential compression of gene expression across dimensionalities and methods reveals no single best method or dimensionality

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  • Site-wide: 15,377
  • In bioinformatics: 1,608
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Comprehensive cross-population analysis of high-grade serous ovarian cancer supports no more than three subtypes

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  • Site-wide: 17,316
  • In cancer biology: 354
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Implicating candidate genes at GWAS signals by leveraging topologically associating domains

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  • Site-wide: 17,672
  • In bioinformatics: 1,872
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  • Site-wide: 104,848

Deconvolution of DNA methylation identifies differentially methylated gene regions on 1p36 across breast cancer subtypes

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  • In genomics: 2,050
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A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma

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  • In genomics: 2,117
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Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

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  • In genomics: 3,045
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  • Site-wide: 4,309
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PathCORE-T: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia

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  • Site-wide: 26,279
  • In bioinformatics: 2,757
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  • Site-wide: 147,008
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Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic

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  • Site-wide: 35,299
  • In pharmacology and toxicology: 209
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  • Site-wide: 39,941

Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma

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  • Site-wide: 44,346
  • In cancer biology: 1,176
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Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual through variant-to-gene mapping

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  • Site-wide: 56,283
  • In genetic and genomic medicine: 280
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Epigenomic profiling of neuroblastoma cell lines

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  • Site-wide: 120,736

Functional network community detection can disaggregate and filter multiple underlying pathways in enrichment analyses

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  • Site-wide: 66,403
  • In bioinformatics: 6,139
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