Author: Wesley K. Thompson

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Preprints

Towards Reproducible Brain-Wide Association Studies

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Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

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  • Site-wide: 2,294
  • In neuroscience: 105
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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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  • Site-wide: 11,080
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Gene-experience correlation during cognitive development: Evidence from the Adolescent Brain Cognitive Development (ABCD) StudySM

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  • Site-wide: 12,113
  • In neuroscience: 1,199
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The female protective effect against autism spectrum disorder

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  • Site-wide: 13,994
  • In genetic and genomic medicine: 81
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Adolescent Brain Cognitive Development (ABCD) Community MRI Collection and Utilities

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  • In neuroscience: 2,866
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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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  • In genetics: 946
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A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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  • Site-wide: 26,627
  • In genetics: 1,062
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Germline variants that influence the tumor immune microenvironment also drive response to immunotherapy

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Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

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  • In genetics: 1,173
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Personalized genetic assessment of age associated Alzheimers disease risk

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  • Site-wide: 35,117
  • In genetics: 1,390
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  • Site-wide: 103,978
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The genetic architecture of human cortical folding

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  • Site-wide: 46,246
  • In genomics: 3,473
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  • Site-wide: 119,643
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Prediction of Neurocognitive Profiles in Youth From Resting State fMRI

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  • In neuroscience: 6,374
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FEMA: Fast and efficient mixed-effects algorithm for population-scale whole brain imaging data

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  • In neuroscience: 7,331
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A simple, consistent estimator of heritability for genome-wide association studies

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  • Site-wide: 52,658
  • In bioinformatics: 5,220
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  • Site-wide: 134,132
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Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

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  • Site-wide: 52,870
  • In genetics: 2,072
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  • Site-wide: 93,247
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  • Site-wide: 122,206

Reliability and Stability Challenges in ABCD Task fMRI Data

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  • Site-wide: 56,692
  • In neuroscience: 7,827
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  • Site-wide: 119,077
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Demographic and Mental Health Assessments in the Adolescent Brain and Cognitive Development Study: Updates and Longitudinal Trajectories

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  • Site-wide: 61,261
  • In psychiatry and clinical psychology: 286
• Year to date:
  • Site-wide: 27,487
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  • Site-wide: 9,984

Spatial gene-by-environment mapping for schizophrenia reveals locale of upbringing effects beyond urban-rural differences

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  • Site-wide: 68,059
  • In epidemiology: 3,142
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Sex-dependent polygenic effects on the clinical progressions of Alzheimer's disease

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  • Site-wide: 70,871
  • In genetics: 2,735
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The Bayesian polyvertex score (PVS-B): a whole-brain phenotypic prediction framework for neuroimaging studies

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  • Site-wide: 73,449
  • In neuroscience: 10,406
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Bayesian Multivariate Growth Mixture Modeling of Longitudinal Data: An Application to Alzheimer's Disease Study

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  • Site-wide: 74,022
  • In neuroscience: 10,642
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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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  • Site-wide: 75,993
  • In bioinformatics: 7,122
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Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

• Downloaded 643 times
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  • Site-wide: 76,833
  • In genetics: 2,959
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

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  • Site-wide: 78,907
  • In genetics: 3,015
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Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations

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  • Site-wide: 82,469
  • In genetic and genomic medicine: 531
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The effect of statistical normalisation on network propagation scores

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  • Site-wide: 85,525
  • In bioinformatics: 7,627
• Year to date:
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  • Site-wide: 212,783

Psychotic-like experiences and polygenic liability in the ABCD Study

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  • Site-wide: 95,008
  • In psychiatry and clinical psychology: 500
• Year to date:
  • Site-wide: 29,808
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  • Site-wide: 20,488

Economic, social, and physiological resilience predict brain structure and cognitive performance in 9 - 10-year-old children

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  • Site-wide: 112,450
  • In neuroscience: 16,273
• Year to date:
  • Site-wide: 129,619
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Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

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  • Site-wide: 118,507
  • In neuroscience: 17,144
• Year to date:
  • Site-wide: 132,890
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  • Site-wide: 214,962

Semi-Parametric Covariate-Modulated Local False Discovery Rate For Genome-Wide Association Studies

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  • Site-wide: 120,498
  • In bioinformatics: 9,979
• Year to date:
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  • Site-wide: 208,100

Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility

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  • Site-wide: 137,538
  • In cancer biology: 4,307
• Year to date:
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  • Site-wide: 26,084

Neural vulnerability and hurricane-related media are associated with post-traumatic stress in youth

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  • Site-wide: 145,195
  • In neuroscience: 22,495
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A nonlinear simulation framework supports adjusting for age when analyzing BrainAGE.

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  • Site-wide: 155,101
  • In bioinformatics: 12,049
• Year to date:
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Prostate cancer risk stratification improved across multiple ancestries with new polygenic hazard score

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  • Site-wide: 164,288
  • In genetic and genomic medicine: 1,180
• Year to date:
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Maturational trajectories of white matter microstructure underlying the right presupplementary motor area reflect individual improvements in motor response cancellation in children and adolescents

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  • Site-wide: 165,747
  • In neuroscience: 24,252
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Common genetic and clinical risk factors: Association with fatal prostate cancer in the Cohort of Swedish Men

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  • Site-wide: 175,043
  • In genetic and genomic medicine: 1,275
• Year to date:
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Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample

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  • Site-wide: 183,789
  • In genetic and genomic medicine: 1,379
• Year to date:
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Alcohol Use Disrupts Age-Appropriate Cortical Thinning in Adolescence: A Data Driven Approach

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  • In neuroscience: 27,229
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Only females show a stable association between neuroticism and microstructural asymmetry of the cingulum across childhood and adolescence: A longitudinal DTI study

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  • Site-wide: 191,985
  • In neuroscience: 28,040
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  • Site-wide: 138,878

Polygenic architecture of a novel MRI endophenotype: the ''Hemochromatosis Brain''

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  • Site-wide: 192,058
  • In neurology: 1,478
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The beneficial effect of sleep on behavioral health problems in youth is disrupted by prenatal cannabis exposure: A causal random forest analysis of ABCD data.

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  • Site-wide: 205,807
  • In pediatrics: 483
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Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models

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  • Site-wide: 213,893
  • In genetics: 7,312
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