Author: Paul Brennan

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Preprints

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

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  • Site-wide: 24,181
  • In genetics: 1,170
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  • Site-wide: 25,554

Whole genome sequencing for diagnosis of neurological repeat expansion disorders

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  • Site-wide: 32,076
  • In genomics: 2,848
• Year to date:
  • Site-wide: 9,805
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  • Site-wide: 16,214

Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data

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  • Site-wide: 33,507
  • In bioinformatics: 3,752
• Year to date:
  • Site-wide: 72,502
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  • Site-wide: 56,599

Trends in excess cancer and cardiovascular deaths in Scotland during the COVID-19 pandemic 30 December 2019 to 20 April 2020

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  • Site-wide: 36,567
  • In epidemiology: 1,780
• Year to date:
  • Site-wide: 33,412
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  • Site-wide: 27,368

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

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  • Site-wide: 44,796
  • In genetics: 2,101
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  • Site-wide: 109,110
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Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

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  • Site-wide: 61,818
  • In bioinformatics: 6,098
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  • Site-wide: 8,346
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Bayesian copy number detection and association in large-scale studies

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  • Site-wide: 103,432
  • In genetics: 4,589
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  • Site-wide: 114,988
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Trans-ethnic genome-wide meta-analysis of 35,732 cases and 34,424 controls identifies novel genomic cross-ancestry loci contributing to lung cancer susceptibility

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  • Site-wide: 105,668
  • In epidemiology: 4,363
• Year to date:
  • Site-wide: 34,716
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  • Site-wide: 31,915

Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: a Mendelian randomization study

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  • Site-wide: 110,272
  • In epidemiology: 4,543
• Year to date:
  • Site-wide: 37,750
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  • Site-wide: 26,305

IL-18 and Lower Risk for Lung Cancer: Triangulated Evidence from Germline Predictions, Pre-Diagnostic Measurements, and Tumor Expression

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  • Site-wide: 130,228
  • In genetic and genomic medicine: 643
• Year to date:
  • Site-wide: 32,180
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  • Site-wide: 10,075

Novel biomarkers of habitual alcohol intake and associations with risk of pancreatic and liver cancers and liver disease mortality

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  • Site-wide: 130,192
  • In epidemiology: 5,259
• Year to date:
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  • Site-wide: 10,113