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Author: John Kuriyan

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  • All-time downloads: 5,437 (rank: 42,527 (tie) )
  • Categories:
    • biochemistry: 3,786 (rank: 748 )
    • bioinformatics: 226 (rank: 37,723 (tie) )
    • biophysics: 1,425 (rank: 3,479 (tie) )

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Preprints

Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases

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CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

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A structural mechanism for the generation of biased agonism in the epidermal growth factor receptor

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Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization

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GHB confers neuroprotection by stabilizing the CaMKIIα hub domain

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Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen

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Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction

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Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites

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Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation

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Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/Calmodulin-dependent protein kinase II

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Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase

bioinformatics more details view paper
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