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Author: Andrew B. Ward

Rankings

  • All-time downloads: 41,201 (rank: 2,959 (tie) )
  • Categories:
    • biochemistry: 2,468 (rank: 1,023 (tie) )
    • bioinformatics: 388 (rank: 26,223 (tie) )
    • biophysics: 8,292 (rank: 160 )
    • immunology: 13,421 (rank: 436 )
    • microbiology: 14,872 (rank: 803 )
    • molecular biology: 366 (rank: 14,121 (tie) )
    • synthetic biology: 1,394 (rank: 1,011 (tie) )

Downloads per author, site-wide

Preprints

Neutralizing antibodies induced by first-generation gp41-stabilized HIV-1 envelope trimers and nanoparticles

microbiology more details view paper

No download data for this paper yet.

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

microbiology more details view paper
  • Downloaded 5,768 times
  • Download rankings, all-time:
    • Site-wide: 1,383
    • In microbiology: 116
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 33,035

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

microbiology more details view paper
  • Downloaded 3,707 times
  • Download rankings, all-time:
    • Site-wide: 2,604
    • In microbiology: 176
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 86,911

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

microbiology more details view paper
  • Downloaded 2,519 times
  • Download rankings, all-time:
    • Site-wide: 4,541
    • In microbiology: 267
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 14,019

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

immunology more details view paper
  • Downloaded 2,325 times
  • Download rankings, all-time:
    • Site-wide: 5,150
    • In immunology: 132
  • Year to date:
    • Site-wide: 2,843
  • Since beginning of last month:
    • Site-wide: 2,198

Cryo-EM structure of the mechanically activated ion channel OSCA1.2

biophysics more details view paper
  • Downloaded 1,943 times
  • Download rankings, all-time:
    • Site-wide: 6,679
    • In biophysics: 135
  • Year to date:
    • Site-wide: 41,926
  • Since beginning of last month:
    • Site-wide: 19,337

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

immunology more details view paper
  • Downloaded 1,783 times
  • Download rankings, all-time:
    • Site-wide: 7,565
    • In immunology: 200
  • Year to date:
    • Site-wide: 1,349
  • Since beginning of last month:
    • Site-wide: 2,201

Structure of the SARS-CoV NSP12 polymerase bound to NSP7 and NSP8 co-factors

biophysics more details view paper
  • Downloaded 1,635 times
  • Download rankings, all-time:
    • Site-wide: 8,658
    • In biophysics: 193
  • Year to date:
    • Site-wide: 11,663
  • Since beginning of last month:
    • Site-wide: 15,084

OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels

biophysics more details view paper
  • Downloaded 1,439 times
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    • Site-wide: 10,459
    • In biophysics: 251
  • Year to date:
    • Site-wide: 48,036
  • Since beginning of last month:
    • Site-wide: 31,616

Tailored Design of Protein Nanoparticle Scaffolds for Multivalent Presentation of Viral Glycoprotein Antigens

synthetic biology more details view paper
  • Downloaded 1,394 times
  • Download rankings, all-time:
    • Site-wide: 11,012
    • In synthetic biology: 123
  • Year to date:
    • Site-wide: 10,101
  • Since beginning of last month:
    • Site-wide: 17,608

Structures of the Otopetrin Proton Channels Otop1 and Otop3

biochemistry more details view paper
  • Downloaded 1,302 times
  • Download rankings, all-time:
    • Site-wide: 12,180
    • In biochemistry: 238
  • Year to date:
    • Site-wide: 31,277
  • Since beginning of last month:
    • Site-wide: 28,497

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

immunology more details view paper
  • Downloaded 1,203 times
  • Download rankings, all-time:
    • Site-wide: 13,745
    • In immunology: 370
  • Year to date:
    • Site-wide: 44,812
  • Since beginning of last month:
    • Site-wide: 84,512

Visualization of the HIV-1 Env Glycan Shield Across Scales

biophysics more details view paper
  • Downloaded 1,063 times
  • Download rankings, all-time:
    • Site-wide: 16,546
    • In biophysics: 442
  • Year to date:
    • Site-wide: 25,633
  • Since beginning of last month:
    • Site-wide: 55,714

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

biochemistry more details view paper
  • Downloaded 974 times
  • Download rankings, all-time:
    • Site-wide: 18,840
    • In biochemistry: 401
  • Year to date:
    • Site-wide: 51,819
  • Since beginning of last month:
    • Site-wide: 29,872

Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

immunology more details view paper
  • Downloaded 935 times
  • Download rankings, all-time:
    • Site-wide: 20,014
    • In immunology: 537
  • Year to date:
    • Site-wide: 34,430
  • Since beginning of last month:
    • Site-wide: 104,740

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

biophysics more details view paper
  • Downloaded 872 times
  • Download rankings, all-time:
    • Site-wide: 22,121
    • In biophysics: 631
  • Year to date:
    • Site-wide: 9,021
  • Since beginning of last month:
    • Site-wide: 25,009

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

microbiology more details view paper
  • Downloaded 809 times
  • Download rankings, all-time:
    • Site-wide: 24,597
    • In microbiology: 1,388
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 37,362

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 677 times
  • Download rankings, all-time:
    • Site-wide: 31,498
    • In microbiology: 1,835
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 81,841

Structure of the Ebola virus nucleoprotein - RNA complex

biophysics more details view paper
  • Downloaded 674 times
  • Download rankings, all-time:
    • Site-wide: 31,684
    • In biophysics: 1,023
  • Year to date:
    • Site-wide: 37,872
  • Since beginning of last month:
    • Site-wide: 57,588

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

immunology more details view paper
  • Downloaded 654 times
  • Download rankings, all-time:
    • Site-wide: 32,999
    • In immunology: 878
  • Year to date:
    • Site-wide: 33,689
  • Since beginning of last month:
    • Site-wide: 32,604

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

immunology more details view paper
  • Downloaded 649 times
  • Download rankings, all-time:
    • Site-wide: 33,268
    • In immunology: 888
  • Year to date:
    • Site-wide: 18,318
  • Since beginning of last month:
    • Site-wide: 42,203

HIV-1 vaccine design through minimizing envelope metastability

microbiology more details view paper
  • Downloaded 644 times
  • Download rankings, all-time:
    • Site-wide: 33,617
    • In microbiology: 1,963
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 96,388

HIV-1 Envelope and MPER antibody structures in lipid assemblies

immunology more details view paper
  • Downloaded 579 times
  • Download rankings, all-time:
    • Site-wide: 38,473
    • In immunology: 1,018
  • Year to date:
    • Site-wide: 23,376
  • Since beginning of last month:
    • Site-wide: 53,101

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

immunology more details view paper
  • Downloaded 559 times
  • Download rankings, all-time:
    • Site-wide: 40,199
    • In immunology: 1,067
  • Year to date:
    • Site-wide: 32,155
  • Since beginning of last month:
    • Site-wide: 28,246

Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

immunology more details view paper
  • Downloaded 540 times
  • Download rankings, all-time:
    • Site-wide: 42,036
    • In immunology: 1,110
  • Year to date:
    • Site-wide: 64,270
  • Since beginning of last month:
    • Site-wide: 43,645

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
  • Downloaded 536 times
  • Download rankings, all-time:
    • Site-wide: 42,356
    • In immunology: 1,125
  • Year to date:
    • Site-wide: 22,459
  • Since beginning of last month:
    • Site-wide: 56,477

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

immunology more details view paper
  • Downloaded 520 times
  • Download rankings, all-time:
    • Site-wide: 43,968
    • In immunology: 1,171
  • Year to date:
    • Site-wide: 50,841
  • Since beginning of last month:
    • Site-wide: 58,272

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 509 times
  • Download rankings, all-time:
    • Site-wide: 45,130
    • In immunology: 1,205
  • Year to date:
    • Site-wide: 2,654
  • Since beginning of last month:
    • Site-wide: 5,654

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

microbiology more details view paper
  • Downloaded 470 times
  • Download rankings, all-time:
    • Site-wide: 49,403
    • In microbiology: 3,099
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 48,255

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

biophysics more details view paper
  • Downloaded 458 times
  • Download rankings, all-time:
    • Site-wide: 50,806
    • In biophysics: 1,801
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 64,106

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

immunology more details view paper
  • Downloaded 440 times
  • Download rankings, all-time:
    • Site-wide: 53,095
    • In immunology: 1,419
  • Year to date:
    • Site-wide: 63,820
  • Since beginning of last month:
    • Site-wide: 88,022

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

immunology more details view paper
  • Downloaded 438 times
  • Download rankings, all-time:
    • Site-wide: 53,346
    • In immunology: 1,424
  • Year to date:
    • Site-wide: 56,918
  • Since beginning of last month:
    • Site-wide: 111,545

Polyclonal epitope cartography reveals the temporal dynamics and diversity of human antibody responses to H5N1 vaccination

immunology more details view paper
  • Downloaded 412 times
  • Download rankings, all-time:
    • Site-wide: 56,911
    • In immunology: 1,514
  • Year to date:
    • Site-wide: 3,660
  • Since beginning of last month:
    • Site-wide: 18,891

EMHP: An accurate automated hole masking algorithm for single-particle cryo-EM image processing

bioinformatics more details view paper
  • Downloaded 388 times
  • Download rankings, all-time:
    • Site-wide: 60,370
    • In bioinformatics: 6,003
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: None

Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

molecular biology more details view paper
  • Downloaded 366 times
  • Download rankings, all-time:
    • Site-wide: 63,817
    • In molecular biology: 1,888
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 34,854

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

immunology more details view paper
  • Downloaded 316 times
  • Download rankings, all-time:
    • Site-wide: 72,305
    • In immunology: 1,941
  • Year to date:
    • Site-wide: 58,148
  • Since beginning of last month:
    • Site-wide: 63,944

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

immunology more details view paper
  • Downloaded 287 times
  • Download rankings, all-time:
    • Site-wide: 77,660
    • In immunology: 2,086
  • Year to date:
    • Site-wide: 61,318
  • Since beginning of last month:
    • Site-wide: 69,122

Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

immunology more details view paper
  • Downloaded 257 times
  • Download rankings, all-time:
    • Site-wide: 83,753
    • In immunology: 2,281
  • Year to date:
    • Site-wide: 68,877
  • Since beginning of last month:
    • Site-wide: 70,842

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

immunology more details view paper
  • Downloaded 217 times
  • Download rankings, all-time:
    • Site-wide: 92,128
    • In immunology: 2,522
  • Year to date:
    • Site-wide: 23,322
  • Since beginning of last month:
    • Site-wide: 37,453

A strain-specific inhibitor of receptor-bound HIV-1 targets a pocket near the fusion peptide and offers a template for drug design

biophysics more details view paper
  • Downloaded 208 times
  • Download rankings, all-time:
    • Site-wide: 94,071
    • In biophysics: 3,666
  • Year to date:
    • Site-wide: 25,995
  • Since beginning of last month:
    • Site-wide: 72,401

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

biochemistry more details view paper
  • Downloaded 192 times
  • Download rankings, all-time:
    • Site-wide: 97,443
    • In biochemistry: 2,899
  • Year to date:
    • Site-wide: 26,471
  • Since beginning of last month:
    • Site-wide: 34,306

High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization

microbiology more details view paper
  • Downloaded 175 times
  • Download rankings, all-time:
    • Site-wide: 100,803
    • In microbiology: 7,467
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 39,030

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

immunology more details view paper
  • Downloaded 138 times
  • Download rankings, all-time:
    • Site-wide: 107,744
    • In immunology: 2,995
  • Year to date:
    • Site-wide: 17,797
  • Since beginning of last month:
    • Site-wide: 27,601

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

immunology more details view paper
  • Downloaded 124 times
  • Download rankings, all-time:
    • Site-wide: 110,346
    • In immunology: 3,090
  • Year to date:
    • Site-wide: 660
  • Since beginning of last month:
    • Site-wide: None

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

microbiology more details view paper
  • Downloaded 103 times
  • Download rankings, all-time:
    • Site-wide: 113,805
    • In microbiology: 8,593
  • Year to date:
    • Site-wide: 19,452
  • Since beginning of last month:
    • Site-wide: 4,806

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