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Author: Andrew B Ward

Rankings

  • All-time downloads: 35,958 (rank: 1,257 out of 424,981)
  • Categories:
    • biochemistry: 2,326 (rank: 949 out of 20,683)
    • bioinformatics: 381 (rank: 24,634 (tie) out of 36,026)
    • biophysics: 7,918 (rank: 151 out of 18,037)
    • immunology: 10,833 (rank: 357 out of 26,030)
    • microbiology: 12,944 (rank: 720 out of 50,033)
    • molecular biology: 263 (rank: 15,245 (tie) out of 23,134)
    • synthetic biology: 1,293 (rank: 1,051 (tie) out of 4,412)

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Preprints

High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization

microbiology more details view paper

No bioRxiv download data for this paper yet.

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

immunology more details view paper

No bioRxiv download data for this paper yet.

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

microbiology more details view paper
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    • In microbiology: 97 out of 8,911
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    • Site-wide: 216 out of 100,621
  • Since beginning of last month:
    • Site-wide: 4,326 out of 100,621

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

microbiology more details view paper
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    • In microbiology: 169 out of 8,911
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    • Site-wide: 423 out of 100,621
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

microbiology more details view paper
  • Downloaded 2,269 times
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    • Site-wide: 143 out of 100,621

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

immunology more details view paper
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    • In immunology: 124 out of 3,123
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Cryo-EM structure of the mechanically activated ion channel OSCA1.2

biophysics more details view paper
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Structure of the SARS-CoV NSP12 polymerase bound to NSP7 and NSP8 co-factors

biophysics more details view paper
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    • In biophysics: 178 out of 4,433
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OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels

biophysics more details view paper
  • Downloaded 1,397 times
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    • In biophysics: 229 out of 4,433
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  • Since beginning of last month:
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Tailored Design of Protein Nanoparticle Scaffolds for Multivalent Presentation of Viral Glycoprotein Antigens

synthetic biology more details view paper
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    • In synthetic biology: 134 out of 917
  • Year to date:
    • Site-wide: 1,584 out of 100,621
  • Since beginning of last month:
    • Site-wide: 12,771 out of 100,621

Structures of the Otopetrin Proton Channels Otop1 and Otop3

biochemistry more details view paper
  • Downloaded 1,249 times
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    • Site-wide: 8,994 out of 100,621
    • In biochemistry: 223 out of 3,441
  • Year to date:
    • Site-wide: 40,802 out of 100,621
  • Since beginning of last month:
    • Site-wide: 27,654 out of 100,621

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

immunology more details view paper
  • Downloaded 1,182 times
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    • Site-wide: 9,875 out of 100,621
    • In immunology: 294 out of 3,123
  • Year to date:
    • Site-wide: 30,926 out of 100,621
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    • Site-wide: 26,032 out of 100,621

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

immunology more details view paper
  • Downloaded 1,114 times
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    • Site-wide: 10,894 out of 100,621
    • In immunology: 319 out of 3,123
  • Year to date:
    • Site-wide: 2,007 out of 100,621
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    • Site-wide: 76 out of 100,621

Visualization of the HIV-1 Env Glycan Shield Across Scales

biophysics more details view paper
  • Downloaded 1,026 times
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    • Site-wide: 12,445 out of 100,621
    • In biophysics: 397 out of 4,433
  • Year to date:
    • Site-wide: 5,025 out of 100,621
  • Since beginning of last month:
    • Site-wide: 14,177 out of 100,621

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

biochemistry more details view paper
  • Downloaded 927 times
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    • Site-wide: 14,641 out of 100,621
    • In biochemistry: 377 out of 3,441
  • Year to date:
    • Site-wide: 5,724 out of 100,621
  • Since beginning of last month:
    • Site-wide: 21,633 out of 100,621

Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

immunology more details view paper
  • Downloaded 913 times
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    • Site-wide: 14,998 out of 100,621
    • In immunology: 428 out of 3,123
  • Year to date:
    • Site-wide: 52,233 out of 100,621
  • Since beginning of last month:
    • Site-wide: 40,169 out of 100,621

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

biophysics more details view paper
  • Downloaded 807 times
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    • Site-wide: 18,172 out of 100,621
    • In biophysics: 639 out of 4,433
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    • Site-wide: 3,243 out of 100,621
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    • Site-wide: 12,163 out of 100,621

Structure of the Ebola virus nucleoprotein - RNA complex

biophysics more details view paper
  • Downloaded 640 times
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    • In biophysics: 972 out of 4,433
  • Year to date:
    • Site-wide: 44,450 out of 100,621
  • Since beginning of last month:
    • Site-wide: 42,796 out of 100,621

HIV-1 vaccine design through minimizing envelope metastability

microbiology more details view paper
  • Downloaded 627 times
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    • Site-wide: 26,360 out of 100,621
    • In microbiology: 1,725 out of 8,911
  • Year to date:
    • Site-wide: 54,283 out of 100,621
  • Since beginning of last month:
    • Site-wide: 39,470 out of 100,621

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

immunology more details view paper
  • Downloaded 613 times
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    • Site-wide: 27,167 out of 100,621
    • In immunology: 760 out of 3,123
  • Year to date:
    • Site-wide: 4,913 out of 100,621
  • Since beginning of last month:
    • Site-wide: 11,883 out of 100,621

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

immunology more details view paper
  • Downloaded 607 times
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    • Site-wide: 27,571 out of 100,621
    • In immunology: 774 out of 3,123
  • Year to date:
    • Site-wide: 4,993 out of 100,621
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    • Site-wide: 14,641 out of 100,621

HIV-1 Envelope and MPER antibody structures in lipid assemblies

immunology more details view paper
  • Downloaded 522 times
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    • Site-wide: 33,433 out of 100,621
    • In immunology: 913 out of 3,123
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    • Site-wide: 17,758 out of 100,621
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    • Site-wide: None out of 100,621

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

immunology more details view paper
  • Downloaded 513 times
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    • Site-wide: 34,100 out of 100,621
    • In immunology: 929 out of 3,123
  • Year to date:
    • Site-wide: 6,491 out of 100,621
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    • Site-wide: 19,403 out of 100,621

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
  • Downloaded 513 times
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    • In immunology: 932 out of 3,123
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    • Site-wide: 64,039 out of 100,621
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    • Site-wide: 41,993 out of 100,621

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

immunology more details view paper
  • Downloaded 494 times
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    • Site-wide: 35,743 out of 100,621
    • In immunology: 982 out of 3,123
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    • Site-wide: 56,085 out of 100,621
  • Since beginning of last month:
    • Site-wide: 28,473 out of 100,621

Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

immunology more details view paper
  • Downloaded 486 times
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    • Site-wide: 36,461 out of 100,621
    • In immunology: 1,014 out of 3,123
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    • Site-wide: 27,657 out of 100,621
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Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

microbiology more details view paper
  • Downloaded 433 times
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    • In microbiology: 2,924 out of 8,911
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    • Site-wide: 8,474 out of 100,621
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    • Site-wide: None out of 100,621

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

immunology more details view paper
  • Downloaded 427 times
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    • Site-wide: 42,386 out of 100,621
    • In immunology: 1,183 out of 3,123
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    • Site-wide: 82,365 out of 100,621
  • Since beginning of last month:
    • Site-wide: 53,845 out of 100,621

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

immunology more details view paper
  • Downloaded 425 times
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    • Site-wide: 42,642 out of 100,621
    • In immunology: 1,190 out of 3,123
  • Year to date:
    • Site-wide: 78,709 out of 100,621
  • Since beginning of last month:
    • Site-wide: 40,040 out of 100,621

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

biophysics more details view paper
  • Downloaded 424 times
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    • Site-wide: 42,773 out of 100,621
    • In biophysics: 1,736 out of 4,433
  • Year to date:
    • Site-wide: 13,825 out of 100,621
  • Since beginning of last month:
    • Site-wide: 9,093 out of 100,621

EMHP: An accurate automated hole masking algorithm for single-particle cryo-EM image processing

bioinformatics more details view paper
  • Downloaded 381 times
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    • In bioinformatics: 5,580 out of 9,245
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    • Site-wide: 90,388 out of 100,621
  • Since beginning of last month:
    • Site-wide: 55,351 out of 100,621

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

microbiology more details view paper
  • Downloaded 310 times
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    • Site-wide: 57,886 out of 100,621
    • In microbiology: 4,321 out of 8,911
  • Year to date:
    • Site-wide: 14,142 out of 100,621
  • Since beginning of last month:
    • Site-wide: 755 out of 100,621

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

immunology more details view paper
  • Downloaded 302 times
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    • Site-wide: 59,096 out of 100,621
    • In immunology: 1,643 out of 3,123
  • Year to date:
    • Site-wide: 42,588 out of 100,621
  • Since beginning of last month:
    • Site-wide: 48,142 out of 100,621

Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

molecular biology more details view paper
  • Downloaded 263 times
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    • Site-wide: 65,485 out of 100,621
    • In molecular biology: 2,119 out of 3,492
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    • Site-wide: 991 out of 100,621

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

immunology more details view paper
  • Downloaded 261 times
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    • Site-wide: 65,734 out of 100,621
    • In immunology: 1,853 out of 3,123
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    • Site-wide: 48,807 out of 100,621
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    • Site-wide: None out of 100,621

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 247 times
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    • Site-wide: 68,254 out of 100,621
    • In microbiology: 5,306 out of 8,911
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    • Site-wide: 19,660 out of 100,621
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    • Site-wide: None out of 100,621

Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

immunology more details view paper
  • Downloaded 223 times
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    • Site-wide: 72,479 out of 100,621
    • In immunology: 2,086 out of 3,123
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Polyclonal epitope cartography reveals the temporal dynamics and diversity of human antibody responses to H5N1 vaccination

immunology more details view paper
  • Downloaded 202 times
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    • Site-wide: 76,121 out of 100,621
    • In immunology: 2,201 out of 3,123
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A strain-specific inhibitor of receptor-bound HIV-1 targets a pocket near the fusion peptide and offers a template for drug design

biophysics more details view paper
  • Downloaded 178 times
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    • Site-wide: 80,422 out of 100,621
    • In biophysics: 3,514 out of 4,433
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    • Site-wide: 30,534 out of 100,621
  • Since beginning of last month:
    • Site-wide: 11,970 out of 100,621

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

biochemistry more details view paper
  • Downloaded 150 times
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    • Site-wide: 84,962 out of 100,621
    • In biochemistry: 2,861 out of 3,441
  • Year to date:
    • Site-wide: 37,699 out of 100,621
  • Since beginning of last month:
    • Site-wide: 20,385 out of 100,621

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

immunology more details view paper
  • Downloaded 80 times
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    • Site-wide: 93,692 out of 100,621
    • In immunology: 2,794 out of 3,123
  • Year to date:
    • Site-wide: 69,832 out of 100,621
  • Since beginning of last month:
    • Site-wide: 6,065 out of 100,621

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