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Author: Andrew B. Ward

  • ORCiD: http://orcid.org/0000-0001-7153-3769
  • Most recently observed institution: Department of Integrative, Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA.

Rankings

  • All-time downloads: 46,993 (rank: 2,995 )
  • Categories:
    • biochemistry: 2,586 (rank: 1,128 )
    • bioinformatics: 406 (rank: 27,951 (tie) )
    • biophysics: 8,648 (rank: 159 )
    • immunology: 16,104 (rank: 485 )
    • microbiology: 17,297 (rank: 810 )
    • molecular biology: 508 (rank: 11,890 (tie) )
    • synthetic biology: 1,444 (rank: 1,072 (tie) )

Downloads per author, site-wide

Preprints

Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

immunology more details view paper

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One dose of COVID-19 nanoparticle vaccine REVC-128 provides protection against SARS-CoV-2 challenge at two weeks post immunization

microbiology more details view paper

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From Structure to Sequence: Identification of polyclonal antibody families using cryoEM

immunology more details view paper

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Murine monoclonal antibodies against RBD of SARS-CoV-2 neutralize authentic wild type SARS-CoV-2 as well as B.1.1.7 and B.1.351 viruses and protect in vivo in a mouse model in a neutralization dependent manner

microbiology more details view paper

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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

microbiology more details view paper
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    • Site-wide: 1,574
    • In microbiology: 134
  • Year to date:
    • Site-wide: 20,320
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    • Site-wide: 20,490

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

microbiology more details view paper
  • Downloaded 3,948 times
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    • Site-wide: 2,782
    • In microbiology: 198
  • Year to date:
    • Site-wide: 12,378
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

microbiology more details view paper
  • Downloaded 2,838 times
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    • Site-wide: 4,461
    • In microbiology: 286
  • Year to date:
    • Site-wide: 6,933
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    • Site-wide: 8,754

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

immunology more details view paper
  • Downloaded 2,597 times
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    • Site-wide: 5,067
    • In immunology: 146
  • Year to date:
    • Site-wide: 5,678
  • Since beginning of last month:
    • Site-wide: 8,816

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

immunology more details view paper
  • Downloaded 2,189 times
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    • Site-wide: 6,530
    • In immunology: 191
  • Year to date:
    • Site-wide: 3,093
  • Since beginning of last month:
    • Site-wide: 3,195

Cryo-EM structure of the mechanically activated ion channel OSCA1.2

biophysics more details view paper
  • Downloaded 1,989 times
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    • Site-wide: 7,519
    • In biophysics: 149
  • Year to date:
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Structure of the SARS-CoV NSP12 polymerase bound to NSP7 and NSP8 co-factors

biophysics more details view paper
  • Downloaded 1,718 times
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    • Site-wide: 9,400
    • In biophysics: 204
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OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels

biophysics more details view paper
  • Downloaded 1,461 times
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    • Site-wide: 11,860
    • In biophysics: 280
  • Year to date:
    • Site-wide: 87,594
  • Since beginning of last month:
    • Site-wide: 72,811

Tailored Design of Protein Nanoparticle Scaffolds for Multivalent Presentation of Viral Glycoprotein Antigens

synthetic biology more details view paper
  • Downloaded 1,444 times
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    • Site-wide: 12,080
    • In synthetic biology: 133
  • Year to date:
    • Site-wide: 39,663
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Structures of the Otopetrin Proton Channels Otop1 and Otop3

biochemistry more details view paper
  • Downloaded 1,325 times
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    • Site-wide: 13,814
    • In biochemistry: 277
  • Year to date:
    • Site-wide: 79,792
  • Since beginning of last month:
    • Site-wide: 65,482

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

immunology more details view paper
  • Downloaded 1,217 times
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    • Site-wide: 15,725
    • In immunology: 451
  • Year to date:
    • Site-wide: 105,691
  • Since beginning of last month:
    • Site-wide: 105,739

Visualization of the HIV-1 Env Glycan Shield Across Scales

biophysics more details view paper
  • Downloaded 1,094 times
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    • Site-wide: 18,384
    • In biophysics: 477
  • Year to date:
    • Site-wide: 63,774
  • Since beginning of last month:
    • Site-wide: 92,949

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

biochemistry more details view paper
  • Downloaded 1,008 times
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    • Site-wide: 20,711
    • In biochemistry: 447
  • Year to date:
    • Site-wide: 64,990
  • Since beginning of last month:
    • Site-wide: 66,204

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

microbiology more details view paper
  • Downloaded 976 times
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    • Site-wide: 21,659
    • In microbiology: 1,232
  • Year to date:
    • Site-wide: 16,668
  • Since beginning of last month:
    • Site-wide: 19,150

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

biophysics more details view paper
  • Downloaded 964 times
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    • Site-wide: 22,096
    • In biophysics: 604
  • Year to date:
    • Site-wide: 23,395
  • Since beginning of last month:
    • Site-wide: 38,825

Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

immunology more details view paper
  • Downloaded 948 times
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    • Site-wide: 22,605
    • In immunology: 658
  • Year to date:
    • Site-wide: 105,971
  • Since beginning of last month:
    • Site-wide: 85,442

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

microbiology more details view paper
  • Downloaded 895 times
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    • Site-wide: 24,624
    • In microbiology: 1,424
  • Year to date:
    • Site-wide: 15,052
  • Since beginning of last month:
    • Site-wide: 22,904

Structure of the Ebola virus nucleoprotein - RNA complex

biophysics more details view paper
  • Downloaded 707 times
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    • Site-wide: 34,167
    • In biophysics: 1,079
  • Year to date:
    • Site-wide: 64,557
  • Since beginning of last month:
    • Site-wide: 70,717

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

immunology more details view paper
  • Downloaded 694 times
  • Download rankings, all-time:
    • Site-wide: 35,127
    • In immunology: 998
  • Year to date:
    • Site-wide: 56,305
  • Since beginning of last month:
    • Site-wide: 114,266

HIV-1 vaccine design through minimizing envelope metastability

microbiology more details view paper
  • Downloaded 666 times
  • Download rankings, all-time:
    • Site-wide: 37,051
    • In microbiology: 2,214
  • Year to date:
    • Site-wide: 110,133
  • Since beginning of last month:
    • Site-wide: 113,074

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

immunology more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 37,112
    • In immunology: 1,062
  • Year to date:
    • Site-wide: 85,128
  • Since beginning of last month:
    • Site-wide: 99,721

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

microbiology more details view paper
  • Downloaded 662 times
  • Download rankings, all-time:
    • Site-wide: 37,327
    • In microbiology: 2,230
  • Year to date:
    • Site-wide: 1,979
  • Since beginning of last month:
    • Site-wide: 1,591

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 649 times
  • Download rankings, all-time:
    • Site-wide: 38,366
    • In immunology: 1,094
  • Year to date:
    • Site-wide: 11,990
  • Since beginning of last month:
    • Site-wide: 29,968

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

microbiology more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 41,506
    • In microbiology: 2,539
  • Year to date:
    • Site-wide: 24,220
  • Since beginning of last month:
    • Site-wide: 23,664

HIV-1 Envelope and MPER antibody structures in lipid assemblies

immunology more details view paper
  • Downloaded 602 times
  • Download rankings, all-time:
    • Site-wide: 42,185
    • In immunology: 1,179
  • Year to date:
    • Site-wide: 75,946
  • Since beginning of last month:
    • Site-wide: 75,421

Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

immunology more details view paper
  • Downloaded 592 times
  • Download rankings, all-time:
    • Site-wide: 43,084
    • In immunology: 1,208
  • Year to date:
    • Site-wide: 48,126
  • Since beginning of last month:
    • Site-wide: 29,155

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

immunology more details view paper
  • Downloaded 574 times
  • Download rankings, all-time:
    • Site-wide: 44,731
    • In immunology: 1,256
  • Year to date:
    • Site-wide: 99,059
  • Since beginning of last month:
    • Site-wide: 101,790

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
  • Downloaded 563 times
  • Download rankings, all-time:
    • Site-wide: 45,791
    • In immunology: 1,273
  • Year to date:
    • Site-wide: 69,323
  • Since beginning of last month:
    • Site-wide: 84,881

Chimpanzee SIV Envelope trimer: structure and deployment as an HIV vaccine template

immunology more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 49,213
    • In immunology: 1,382
  • Year to date:
    • Site-wide: 121,490
  • Since beginning of last month:
    • Site-wide: 105,989

Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

molecular biology more details view paper
  • Downloaded 508 times
  • Download rankings, all-time:
    • Site-wide: 51,816
    • In molecular biology: 1,477
  • Year to date:
    • Site-wide: 24,968
  • Since beginning of last month:
    • Site-wide: 34,558

Polyclonal epitope cartography reveals the temporal dynamics and diversity of human antibody responses to H5N1 vaccination

immunology more details view paper
  • Downloaded 494 times
  • Download rankings, all-time:
    • Site-wide: 53,504
    • In immunology: 1,503
  • Year to date:
    • Site-wide: 21,346
  • Since beginning of last month:
    • Site-wide: 30,429

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

biophysics more details view paper
  • Downloaded 494 times
  • Download rankings, all-time:
    • Site-wide: 53,497
    • In biophysics: 1,847
  • Year to date:
    • Site-wide: 88,988
  • Since beginning of last month:
    • Site-wide: 74,584

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

immunology more details view paper
  • Downloaded 446 times
  • Download rankings, all-time:
    • Site-wide: 59,791
    • In immunology: 1,663
  • Year to date:
    • Site-wide: 128,035
  • Since beginning of last month:
    • Site-wide: 129,561

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

immunology more details view paper
  • Downloaded 443 times
  • Download rankings, all-time:
    • Site-wide: 60,186
    • In immunology: 1,672
  • Year to date:
    • Site-wide: 134,488
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    • Site-wide: None

EMHP: An accurate automated hole masking algorithm for single-particle cryo-EM image processing

bioinformatics more details view paper
  • Downloaded 406 times
  • Download rankings, all-time:
    • Site-wide: 65,733
    • In bioinformatics: 6,373
  • Year to date:
    • Site-wide: 111,969
  • Since beginning of last month:
    • Site-wide: 107,266

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

immunology more details view paper
  • Downloaded 351 times
  • Download rankings, all-time:
    • Site-wide: 75,085
    • In immunology: 2,099
  • Year to date:
    • Site-wide: 4,856
  • Since beginning of last month:
    • Site-wide: 11,046

A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutinin

immunology more details view paper
  • Downloaded 349 times
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    • Site-wide: 75,359
    • In immunology: 2,113
  • Year to date:
    • Site-wide: 4,900
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    • Site-wide: 2,136

Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects

immunology more details view paper
  • Downloaded 332 times
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    • Site-wide: 78,766
    • In immunology: 2,187
  • Year to date:
    • Site-wide: 5,307
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    • Site-wide: 1,486

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

immunology more details view paper
  • Downloaded 329 times
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    • Site-wide: 79,304
    • In immunology: 2,203
  • Year to date:
    • Site-wide: 116,640
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    • Site-wide: 132,867

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

immunology more details view paper
  • Downloaded 298 times
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    • Site-wide: 85,634
    • In immunology: 2,389
  • Year to date:
    • Site-wide: 121,895
  • Since beginning of last month:
    • Site-wide: 133,211

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

immunology more details view paper
  • Downloaded 292 times
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    • Site-wide: 86,747
    • In immunology: 2,430
  • Year to date:
    • Site-wide: 6,380
  • Since beginning of last month:
    • Site-wide: 7,066

Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

immunology more details view paper
  • Downloaded 271 times
  • Download rankings, all-time:
    • Site-wide: 91,451
    • In immunology: 2,582
  • Year to date:
    • Site-wide: 117,426
  • Since beginning of last month:
    • Site-wide: 114,020

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

microbiology more details view paper
  • Downloaded 271 times
  • Download rankings, all-time:
    • Site-wide: 91,267
    • In microbiology: 6,561
  • Year to date:
    • Site-wide: 7,145
  • Since beginning of last month:
    • Site-wide: 9,058

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

immunology more details view paper
  • Downloaded 269 times
  • Download rankings, all-time:
    • Site-wide: 91,919
    • In immunology: 2,595
  • Year to date:
    • Site-wide: 7,229
  • Since beginning of last month:
    • Site-wide: 18,249

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

biochemistry more details view paper
  • Downloaded 253 times
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    • Site-wide: 95,393
    • In biochemistry: 2,768
  • Year to date:
    • Site-wide: 38,333
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    • Site-wide: 26,468

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

immunology more details view paper
  • Downloaded 243 times
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    • Site-wide: 97,489
    • In immunology: 2,754
  • Year to date:
    • Site-wide: 70,744
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    • Site-wide: 67,647

A strain-specific inhibitor of receptor-bound HIV-1 targets a pocket near the fusion peptide and offers a template for drug design

biophysics more details view paper
  • Downloaded 221 times
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    • Site-wide: 102,362
    • In biophysics: 3,953
  • Year to date:
    • Site-wide: 99,554
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    • Site-wide: 114,192

High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization

microbiology more details view paper
  • Downloaded 220 times
  • Download rankings, all-time:
    • Site-wide: 102,652
    • In microbiology: 7,526
  • Year to date:
    • Site-wide: 63,751
  • Since beginning of last month:
    • Site-wide: 115,508

Neutralizing antibodies induced by first-generation gp41-stabilized HIV-1 envelope trimers and nanoparticles

microbiology more details view paper
  • Downloaded 169 times
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    • Site-wide: 113,685
    • In microbiology: 8,552
  • Year to date:
    • Site-wide: 44,976
  • Since beginning of last month:
    • Site-wide: 30,712

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

immunology more details view paper
  • Downloaded 167 times
  • Download rankings, all-time:
    • Site-wide: 114,183
    • In immunology: 3,241
  • Year to date:
    • Site-wide: 63,185
  • Since beginning of last month:
    • Site-wide: 57,615

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

microbiology more details view paper
  • Downloaded 125 times
  • Download rankings, all-time:
    • Site-wide: 122,652
    • In microbiology: 9,364
  • Year to date:
    • Site-wide: 76,403
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    • Site-wide: 125,534

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