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Author: Christopher Cottrell

Rankings

  • All-time downloads: 17,443 (rank: 16,747 (tie) )
  • Categories:
    • biochemistry: 1,408 (rank: 5,038 (tie) )
    • biophysics: 1,165 (rank: 6,081 (tie) )
    • immunology: 12,612 (rank: 1,089 )
    • microbiology: 314 (rank: 54,185 (tie) )

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Preprints

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

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Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

immunology more details view paper
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    • In immunology: 778
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Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

immunology more details view paper
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    • Site-wide: 25,257
    • In immunology: 1,140
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Visualization of the HIV-1 Env Glycan Shield Across Scales

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Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

biochemistry more details view paper
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    • In biochemistry: 614
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Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

immunology more details view paper
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From Structure to Sequence: Identification of polyclonal antibody families using cryoEM

immunology more details view paper
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    • Site-wide: 33,470
    • In immunology: 1,119
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Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

immunology more details view paper
  • Downloaded 841 times
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    • In immunology: 1,496
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Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

immunology more details view paper
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Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

immunology more details view paper
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    • In immunology: 1,636
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Mapping polyclonal antibody responses in non-human primates vaccinated with HIV Env trimer subunit vaccines

immunology more details view paper
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    • Site-wide: 57,021
    • In immunology: 1,718
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Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

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    • In immunology: 1,779
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Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
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    • In immunology: 1,908
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Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

immunology more details view paper
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    • Site-wide: 74,711
    • In immunology: 2,448
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A broad and potent neutralization epitope in SARS-related coronaviruses

microbiology more details view paper
  • Downloaded 557 times
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    • Site-wide: 77,037
    • In microbiology: None
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Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

immunology more details view paper
  • Downloaded 531 times
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    • Site-wide: 81,525
    • In immunology: 2,388
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Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

immunology more details view paper
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    • Site-wide: 91,121
    • In immunology: 2,608
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    • Site-wide: 179,135
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Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

immunology more details view paper
  • Downloaded 381 times
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    • Site-wide: 115,065
    • In immunology: 3,320
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HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

immunology more details view paper
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Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

biochemistry more details view paper
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    • In biochemistry: 3,527
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Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

immunology more details view paper
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    • In immunology: 3,702
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High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization

microbiology more details view paper
  • Downloaded 330 times
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    • In microbiology: 8,581
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Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

immunology more details view paper
  • Downloaded 268 times
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    • Site-wide: 147,613
    • In immunology: 4,253
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Efficient isolation of rare B cells using next-generation antigen barcoding

immunology more details view paper
  • Downloaded 261 times
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    • Site-wide: 149,896
    • In immunology: None
  • Year to date:
    • Site-wide: 13,230
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